|
The document reports the results of an acute inhalation toxicity study on a mixture of perfluorinated compounds, including various ammonium salts, which revealed high mortality in rats exposed to concentrations of 120 mg/m3 and 57 mg/m3, while all rats at 23 mg/m3 survived, indicating significant toxicity at higher exposure levels.
|
2002 |
AR226-1057
|
gan57pwN1DpXvdJzX07X7noV |
1 |
|
The Fire Fighting Foam Coalition provided the EPA with information on the chemistry and quantity of fluorosurfactants, specifically noting that approximately 138,000 pounds of these substances were used in the production of aqueous film-forming foam (AFFF) agents sold in the U.S. in 1999, primarily focusing on telomer-based AFFF agents.
|
2002 |
AR226-1065
|
3ejGN47gK3g3oB7GN3wV92EB6 |
1 |
|
This is a letter from Thomas A. Cortina, Executive Director of the Fire Fighting Foam Coalition, addressing Mr. Auer regarding issues related to firefighting foam and its environmental implications.
|
2002 |
AR226-1075
|
evOmG2z1kzYaeob2yqEDd6p3M |
1 |
|
3M submitted a TSCA 8(e) substantial risk notice to the EPA regarding Ammonium Perfluorooctanoate (APFO), CAS#: 3825-26-1, highlighting statistically significant adverse effects observed in a reproduction study in rats, while noting that further analysis is needed to determine the causation of these effects.
|
2002 |
AR226-1081
|
LpxEE5Qd6a2xN2v15VazjG9ag |
1 |
|
The document is a submission from 3M to the EPA providing the final report of a two-generation reproduction study in rats on Ammonium Perfluorooctanoate (CAS# 3825-26-1) as part of TSCA 8(e) substantial risk notification.
|
2002 |
AR226-1091
|
kaBK8Byag98QEyNzGXqOq8Q3n |
1 |
|
3M submitted additional data to the EPA regarding perfluorooctane sulfonates, including a final report on a two-generation reproduction study of ammonium perfluorooctanoate in rats, which analyzes the effects of gestational age and body weight on reproductive outcomes.
|
2002 |
AR226-1095
|
np72DGvJbmvqEmyOKdMeBxpxG |
1 |
|
3M submitted a TSCA 8(e) substantial risk notice to the EPA regarding a rat study on triphenylbenzyl phosphonium cation/N-Methyl perfluorooctanesulfonamide salt, indicating significant toxicity at higher doses and identifying a No Observable Adverse Effect Level (NOAEL) at 5 mg/kg.
|
2002 |
AR226-1097
|
jyY4p2pp8g2DLYZwdxdGzM1OZ |
1 |
|
The document is a letter from the EPA's Office of Prevention, Pesticides and Toxic Substances announcing the availability of the Revised Draft Hazard Assessment of Perfluorooctanoic Acid (PFOA) and its salts, which updates previous assessments and incorporates new studies and comments received through October 2002.
|
2002 |
AR226-1135
|
zmjBYbGYEYX5LjvBe2jG6qyR |
1 |
|
The document is a communication from the EPA regarding the Revised Draft Hazard Assessment of Perfluorooctanoic Acid (PFOA) and its salts, which updates previous assessments by incorporating new studies, including a two-generation reproductive study in rats and a six-month monkey study.
|
2002 |
AR226-1130
|
wNVRY4mGNYDkg8Dw30L4mzG6 |
1 |
|
This is a letterhead cover page from an unspecified organization, with no analytical content retained in the OCR.
|
2002 |
AR226-1143
|
5kjgJoJV6B62xvyOrwmV8VMde |
1 |
|
The document summarizes a meeting on October 17, 2002, between EPA officials and DuPont representatives to discuss perfluorooctanoic acid (PFOA) and ammonium perfluorooctanoate (APFO), focusing on DuPont's product stewardship efforts and their plans to assess PFOA exposure related to fluoropolymer manufacturing and telomer breakdown.
|
2002 |
AR226-1139
|
peGYZGy7J71oyJBydgo7KERXw |
1 |
|
This is a letter from DuPont's Robert C. Buck transmitting two disks containing a sanitized and a confidential presentation to the U.S. EPA from a meeting held on November 25, 2002.
|
2002 |
AR226-1146
|
93Dvpb1KypOzEJ7vz35OyazOq |
1 |
|
This is a letter from the EPA's Office of Prevention, Pesticides and Toxic Substances, dated December 9, 2002, addressed to interested parties regarding unspecified content related to environmental protection.
|
2002 |
AR226-1144
|
44prQ9K4ZQ4dDwQvKRpdoKyrG |
1 |
|
The Environmental Working Group received a letter from the Little Hocking Water Association expressing concerns about C-8 (PFOA) contamination in their drinking water supply, with levels detected as high as 78.0 ppb, significantly exceeding those found in West Virginia's water supplies.
|
2002 |
AR226-1158
|
MM2gmxd72m5464ErNB1MGgR1x |
1 |
|
This document is a letter from Robert A. Bilott to Mary Dominiak at the EPA, submitting various documents for inclusion in Administrative Record 226 related to PFOA (ammonium perfluorooctanoate), including letters and submissions to the IRIS database.
|
2002 |
AR226-1159
|
6vXvdNDmr604jx2KOQdO93k1 |
1 |
|
The document is a progress report from 3M regarding the phase-out of certain perfluorosulfonyl fluoride (PFOS) derivatives, confirming that as of December 31, 2000, 3M has ceased manufacturing these derivatives in various product categories and is meeting reduced production goals for extended use categories.
|
2001 |
AR226-0997
|
5LxqGbxaMpnvgdnL91kYVDvz5 |
1 |
|
The document is a correspondence from the EPA requesting DuPont Haskell Laboratory to provide the complete data set of blood concentrations related to Ammonium Perfluorooctanoate (AFPO) as summarized in their report.
|
2001 |
AR226-1003
|
rMQm9Jzdx1kDqm6BRmg0qypE |
1 |
|
The document summarizes a March 7, 2001 meeting between the EPA and the Fluoropolymer Manufacturing Group, where concerns were raised about the discontinuation of ammonium perfluorooctanoate (APFO) production by 3M and the need for ongoing toxicology research and risk assessment related to APFO and perfluorooctanoic acid (PFOA).
|
2001 |
AR226-1007
|
mBGYNGpp4GGy3GNdwLdGVZexb |
1 |
|
The document is a facsimile cover letter from Allen C. Weidman of The Society of the Plastics Industry, Inc. (SPI) clarifying the status of Confidential Business Information (CBI) related to submissions on PFOA made to the EPA on April 13, 2001, and March 7, 2001.
|
2001 |
AR226-1008
|
Qk6NY2bLygxrDynzeb2OKK2Qk |
1 |
|
The document is a letter from Allen Weidman, Executive Director of the Fluoropolymer Manufacturers Group, to Mr. Charles Auer of the EPA, outlining their toxicology program, including a bio-monitoring test protocol and plans to discuss alternatives to fluoropolymer manufacturing processes.
|
2001 |
AR226-1009
|
XR2ypbpMpwpQ0J12D2wJeddRJ |
1 |
|
The document is a note summarizing a meeting held on March 28, 2001, between the EPA and 3M to discuss the status of 3M's testing program, phase-out plan for PFOS, and related OECD activities.
|
2001 |
AR226-1013
|
O1ZdN6odbBNoE9VBkdLvNjz61 |
1 |
|
3M submitted a TSCA 8(e) notice to the EPA detailing acute toxicity studies on perfluorooctane sulfonate (PFOS) conducted on honey bees, reporting a contact LD50 of 59.7 mg/Kg (moderately toxic) and an oral LD50 of 5 mg/Kg (highly toxic).
|
2001 |
AR226-1016
|
MJmManMjvpLzKeozZ7XwpGxra |
1 |
|
The document is a letter from the EPA to DuPont Haskell Laboratory requesting clarification on why results related to ammonium perfluorooctanoate (PFOA) were submitted as voluntary rather than under TSCA Section 8(e), given potential human health hazard concerns.
|
2001 |
AR226-1025
|
g2daZ926nLq4mqkyLORLbrVZ9 |
1 |
|
The document is a letter from the EPA to 3M Company regarding the submission of information on perfluorooctane sulfonates (PFOS) and related compounds, confirming its placement in the TSCA Public Docket as part of Administrative Record 226.
|
2001 |
AR226-1031
|
jN3L70pjzML3ez0m0Ln4qKnoO |
1 |
|
3M submitted two studies on perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) related to clinical chemistry and health outcomes from employee participants in their Fluorochemical Medical Surveillance Program to the EPA as part of their ongoing dialogue regarding fluorochemicals.
|
2001 |
AR226-1046
|
q51bGRm7bjaKOkQQ3RNaVXkK |
1 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under the Toxic Substances Control Act.
|
— |
AR226-0994
|
e7zQ0Rb9QvazVqBX6NB7XDwKE |
1 |
|
This is a TSCA NCIC Notification Form indicating that the document contains confidential business information protected under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-0995
|
5LR69V83qo4XmJMMmKqkZVx4e |
1 |
|
Unreadable document.
|
— |
AR226-0999
|
K6q5Bbkdz9j2mKZk4ebMGNZxQ |
1 |
|
Unreadable document.
|
— |
AR226-1002
|
oo1GnZnDag4jJRV84D77x5Lo |
1 |
|
Unreadable document.
|
— |
AR226-1014
|
xjozYjnqzrmQvEnYdmYnn6q4b |
1 |
|
Chemguard Inc. submitted confidential information regarding their AFFF type foam concentrate, Chemguard FS-100, which contains a proprietary fluorochemical surfactant and is manufactured at 40% solids in water.
|
— |
AR226-1040
|
2jQrvndmyx0MZo122raexrw0N |
1 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-1071
|
Radp6e2vpzppaaaBJyLKn4J88 |
1 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under the Toxic Substances Control Act.
|
— |
AR226-1119
|
nNaMGyy1M0qQ6z4Dw62Xm4pzz |
1 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-1118
|
3No4Ekwn6bJ9VYJG8MEVQyrbE |
1 |
|
Unreadable document.
|
— |
AR226-1142
|
ZJmpDK33vy4NxweVr5BZEnBDd |
1 |