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Title / Summary Year AR226 Docket Hash ID Pages
This analytical report details the air sampling program conducted by DuPont Corporation, where seven air samples were analyzed for Perfluorooctanoic Acid (PFOA) using liquid chromatography/mass spectrometry (LCMS) by Exygen Research. AR226-2660 eLJvJxkp10rwzzgEEg8w4Kry 18
The document is an analytical report from Exygen Research detailing the air sampling program for Perfluorooctanoic Acid (PFOA) conducted by DuPont Corporation, which includes sample collection and analysis methods, with one sample reported as having collection issues. AR226-2661 3JnDm8eVdk2zYzYe9nadG5KDO 18
The document is an air sampling report from Exygen Research analyzing samples collected from DuPont Washington Works for Perfluorooctanoic Acid (PFOA) using liquid chromatography mass spectrometry, noting that one sample had collection issues and no results were reported for it. AR226-2662 r60Goa9wkRaOq4yXYB4Q5mNRV 18
The document reports on a study conducted by Haskell Laboratory for Toxicology and Industrial Medicine, which found that ammonium perfluorooctanoate (APFO) did not demonstrate teratogenic potential in rats, although maternal toxicity and some adverse effects were observed at the highest exposure levels. AR226-2818 5DxMZv2w1N5rwdra0gmLdEkw4 34
The document is a report from Haskell Laboratory for Toxicology and Industrial Medicine evaluating the toxicity of a substance, likely related to PFOA or PFOS, in male rats and rabbits, indicating that the tested compound does not classify as a class "B" poison under ICC regulations. AR226-2819 QkXKZQ4qzGdaro6yRY24nNM6E 1
The document reports on a subacute oral toxicity study of PFOA conducted by E. I. du Pont de Nemours and Company, indicating that doses of 5,000 mg/kg/day resulted in mortality and toxic signs such as weight loss and diarrhea in test rats. AR226-2820 gDDLzjJ6LYa4pVjb1B3ep3DKG 3
The document reports on the results of subacute oral tests and acute tests on rats and rabbits using test materials H-3824 and H-3825, indicating slight toxicity signs and weight changes in rats and no mortality in rabbits at high doses, suggesting a low acute toxicity profile for the tested perfluorinated compounds. AR226-2821 995rQwrdegkRXNwrgNoL29goD 3
The document reports on toxicity testing of a perfluorinated compound mixture, revealing that exposure to concentrations of 40,000 ppm resulted in high mortality and significant respiratory distress in rats, while lower concentrations showed varying survival rates and clinical signs of toxicity. AR226-2822 zQ5bLadpX8EGd09V3M9KBXgr3 5
The document is a laboratory report detailing the results of an acute oral toxicity study on a suspension containing a perfluorinated compound, indicating nonlethal effects at various doses, with observed symptoms including diarrhea and weight loss at higher doses. AR226-2826 x5K23QqOxwkqpqO47o097G0rb 3
The document reports on an acute inhalation toxicity study conducted by E. I. du Pont de Nemours and Company at Haskell Laboratory, which evaluated the effects of a test material on male rats, revealing varying mortality rates and clinical signs such as irregular respiration and convulsions, with specific concentrations of the test material measured during exposure. AR226-2827 XwDY6XrObE78q90pV1e840Ky 2
The document reports on an acute oral toxicity test of an unspecified organic chemical, likely related to PFOA or PFOS, conducted by Haskell Laboratory, which found that the approximate lethal dose (ALD) for young adult male rats is 17,000 mg/kg when administered by intragastric intubation. AR226-2828 1gvz2bNOkYLzvygxRd3L0NvQm 2
The Haskell Laboratory Report No. 244-71 presents results from acute and subacute oral toxicity tests on a perfluorinated compound, indicating no mortality or significant organ changes in young adult rats at various doses, with liver weights measured post-dosing. AR226-2829 k9v1eONYB8Gv0XzLvLbKeR3wE 3
The document reports on acute oral toxicity testing of a test material submitted by E. I. du Pont de Nemours and Company, indicating that no clinical signs were observed in young adult ChR-CD male rats after administration of various doses, with liver weights recorded post-sacrifice. AR226-2830 NGrk5d2VvjQgMgOrmwjVk7M8b 3
The document reports on acute and subacute oral toxicity tests of a test material, likely related to PFOA or PFOS, administered to rats, indicating no mortality and no compound-related abnormalities in various organs after dosing. AR226-2831 reMkbqe0qE1zm7K9ZZdKG2E4r 3
The document is a report from Haskell Laboratory detailing primary skin irritation and sensitization tests on guinea pigs using a test material, likely related to PFOA or PFOS, which showed no sensitization or significant irritation at the concentrations tested. AR226-2835 dn0eERezYv2aJjDzOpVE8aeB5 2
This is a Haskell Laboratory report (No. 275-73) detailing primary skin irritation and sensitization tests conducted on guinea pigs for E. I. du Pont de Nemours and Company. AR226-2836 Bym8ON3npEz4xyZ2OXn344Ob8 2
This analytical report details the air sampling program conducted by DuPont Washington Works, where seven air samples were analyzed for Perfluorooctanoic Acid (PFOA) using liquid chromatography/mass spectrometry, with one sample excluded due to collection issues. AR226-2663 GmkE943qGRX1XJ2d62wgr9Xkm 18
The document is an analytical report from Exygen Research detailing the air sampling program conducted by DuPont Washington Works, specifically analyzing samples for Perfluorooctanoic Acid (PFOA) using liquid chromatography/mass spectrometry (LCMS). AR226-2664 9JbvQ0dj2V3D2aXe1ok1Rd1w6 21
This analytical report details the air sampling program conducted by DuPont at their Washington Works facility, specifically analyzing samples for Perfluorooctanoic Acid (PFOA) using liquid chromatography/mass spectrometry (LCMS), with one sample excluded due to a sampler malfunction. AR226-2665 NG4rrKj5JKyoGO8D8eLnjRbo8 18
This analytical report details the air sampling program conducted by DuPont at the Washington Works facility, specifically analyzing samples for Perfluorooctanoic Acid (PFOA) using liquid chromatography/mass spectrometry (LCMS). AR226-2666 GKwN0jdVnX3zZvdxqdpzGVa84 17
This document outlines a draft test plan for measuring the particle size distribution of airborne PFOA and APFO emissions from the E. I. DuPont manufacturing facility in Parkersburg, West Virginia, to understand their transport in ambient air. AR226-2667 r67YaZwMrEOm9Nwj5Rq1j86pa 14
The document summarizes a particle size distribution (PSD) analysis of PFOA in ambient air conducted at the DuPont Washington Works site, revealing an average PSD and 72-hour average ambient air concentrations that compare favorably with previous measurements, indicating acceptable precision in the sampling methodology. AR226-2668 91NEyNaq90ovy5VwKNVLRVMeV 22
DuPont submitted air monitoring data related to PFOA from their Washington Works facility in West Virginia to the EPA, including intermediate results from an Air Modeling Verification Study and particle size distribution analysis for PFOA in ambient air. AR226-2670 g2mgjaam89Ga43MwRqopg63yq 8
The document is a revised air dispersion modeling analysis of APFO emissions conducted by DuPont at its Washington Works facility in Parkersburg, West Virginia, covering the period from September 2002 to August 2003, and includes updates to stack parameters based on testing results. AR226-2669 6RpkZ1oQpqpVq8y5Z7eezEjm 10
to analyze the vertical mobility of PFOA through soil columns to understand its leaching behavior in response to artificial rain, as part of a study conducted by DuPont in August 2004. AR226-2671 6RxveXvNpMmvn7Dr4bwG2XVm6 42
The document reports on a primary irritation test conducted on guinea pigs using a 50% concentration of an unspecified perfluorinated compound, indicating no sensitization reactions were observed in the test subjects. AR226-2837 N2jVZNzRLzXyonKkdKqK4gw58 2
This is a laboratory report detailing the acute toxicity bioassay of compound 8230 on rainbow trout, conducted by Bionomics, Inc. in Wareham, Massachusetts, with results indicating a TL^0 value greater than 1000 mg/l for both 24-hour and 96-hour exposure periods. AR226-2838 060r2ELLxD42rM7yR21nNL4oV 7
The Haskell Laboratory Report No. 372-73 details an acute oral toxicity test of a perfluorinated compound in young adult ChR-CD male rats, finding it to be slightly toxic with an approximate lethal dose of 1,500 mg/kg and causing liver enlargement at doses of 450 mg/kg and above. AR226-2841 RpMQx38Ng90xMxpJZpEX2wpYv 2
The document reports on eye irritation tests conducted on a sample identified as H-8524 for E. I. Du Pont de Nemours & Company, indicating that both washed and unwashed eyes of albino rabbits showed minimally irritating effects with maximum irritation scores of 11.0 and 15.0, respectively. AR226-2844 bJvX8x8n8LmD4vXVRxd4xbEO 10
The document is a Haskell Laboratory report detailing an eye irritation test conducted on rabbits using a test material identified as Haskell No. 9805, which is associated with E. I. du Pont, de Nemours and Company, and shows mild ocular effects such as redness and swelling. AR226-2845 pp4YR6nz3Zn4QG58DxZvo1MMD 2
The document reports on primary skin irritation and sensitization tests conducted by Du Pont de Nemours and Company on a test material, indicating that the substance produced mild reactions in guinea pigs. AR226-2846 OEn9L6n81LMDvjNMmLDKYo8Bv 2
The document reports on an acute oral toxicity test conducted by Haskell Laboratory for Toxicology and Industrial Medicine, detailing the lethal and non-lethal effects of a substance (likely PFOA or PFOS) at various doses, with findings of mortality and clinical signs such as lethargy and diarrhea at doses as low as 5,000 mg/kg. AR226-2847 gE2ogg0yZa6aRJqogNxXn0N39 3
The document reports on a study conducted by E. I. du Pont de Nemours and Company at the Haskell Laboratory, which involved exposing ten healthy male beagle dogs to a test mixture containing PFOA, with the aim of monitoring their electrocardiograms and analyzing air samples for PFOA concentration. AR226-2848 2RywbD2Qqv8xDg1maaYmbqVpL 2
The Haskell Laboratory Report No. 68-73 details a ninety-day feeding study of PFOA in rats and dogs, revealing no significant toxicity at lower levels, but indicating that higher dietary levels (750 and 2,500 ppm) resulted in decreased erythrocyte counts and organ weight changes, particularly in male rats, with some reversible histological changes observed in the livers of those AR226-2832 LprRmjzRN257gLqrJ2GJ1bJkq 95
This document contains analytical results for PFOA from air sampling conducted in 2003 and 2004, with multiple samples reporting concentrations below detection limits. AR226-2673 baran79BGNqQNr8dpBBOGxEZg 7
The document reports on a study evaluating the biodegradability of a perfluorinated compound using the closed bottle test, conducted by DuPont and completed in 1995. AR226-2680 bBXVLJ7kxB21x5raj1oMdgJ16 9
This document appears to be a data summary for various water and soil samples analyzed for FC-143, detailing sample dates, types, and concentrations, but lacks a clear report format. AR226-2674 ppNxBQBwwqgawab5rg0rm2Gb7 60
This document contains analytical results for C8 sampling conducted in 1996-2001, detailing various surface water and groundwater samples with measurements of FC-143 concentrations from multiple outfalls and outlets. AR226-2675 150vwe7Ydjxw7vjByKyEVzb95 45
This document appears to be a summary of groundwater sampling results for various wells, including data from multiple years, with a focus on C8 compounds, specifically FC-143. AR226-2672 m4Gazd17779o7drYOQK1ay64 108
The document discusses the biodegradation of C-8 (perfluorooctanoic acid, PFOA) in groundwater, detailing its concentration levels, hydrogeological context, and methods for analyzing its degradation rates and transport in the Lubeck well field. AR226-2682 6byrZ5EM0k6EVXj6QBGzq5DK6 19
This document appears to be a summary of annual C8 sampling results from 1997 to 2000, detailing various groundwater and leachate samples analyzed for the presence of FC-143 by an unspecified laboratory. AR226-2677 jgRaQ5daGegZv16e2Dq92LeO 39
This document appears to be a summary of annual C8 sampling results from various locations, including Lower Pond and Upper Pond, spanning multiple years from 1991 to 2000, but lacks specific analytical content. AR226-2676 1g7Xqmrv9bD95kaQB92Bmnadq 48
This is a report from Huntingdon Life Sciences detailing a preliminary test on abiotic degradation through hydrolysis as a function of pH, including compliance with good laboratory practice standards and quality assurance statements. AR226-2683 b5D8NVv66oGmoVDYOy3nnwozg 13
The document reports on adsorption-desorption screening studies of ammonium perfluorooctanoate (APFO) conducted by E. I. du Pont de Nemours and Company, finding that five out of nine tested materials significantly adsorbed APFO, with most of the adsorbed APFO not desorbing after washing. AR226-2684 G6gagDvZ5RpN5RpZq1dwNrzbq 17
The document discusses the thermal stability of PTFE and FEP, highlighting that previous estimates of HFP and TFA production from PTFE pyrolysis at 500°C were significantly overestimated, necessitating further research to provide accurate data for internal and external inquiries regarding these fluorinated compounds. AR226-2685 a13BnXDbgMm8gVwXV0v9qEp2N 8
The document reports the results of analyses for perfluorooctanoic acid (PFOA) in soil and groundwater samples collected from the E. I. DuPont de Nemours and Company facility in Parkersburg, West Virginia, indicating PFOA concentrations ranging from 49 to 53 ppb in groundwater samples. AR226-2681 KR18a5onYxMJwpxMm2B26p9gX 127
The Haskell Laboratory report No. 825-76 details an eye irritation test conducted on rabbits using a test material from E. I. du Pont de Nemours and Company, which resulted in temporary mild ocular effects, including slight corneal opacity and conjunctivitis, with full recovery observed within 7 days. AR226-2852 a1pOVKYN05gqoQyRv400N2R99 2
The Haskell Laboratory Report No. 1003-76 indicates that the tested material (Haskell No. 10,642) produced no irritation or significant sensitization in male albino guinea pigs when applied at 100% concentration and as a 10% aqueous solution, although it may be considered a very weak sensitizer based on the observed reactions. AR226-2854 0gnoYEdQoZBn3KywJV43dRRzm 2
The document is a laboratory report from Haskell Laboratory detailing a skin irritation and sensitization test conducted on guinea pigs using a textile fiber material, with findings indicating varying levels of negative reactions to different concentrations of the test substance. AR226-2857 g2Er9MNJLLbdzNdgKN5rwrGQa 2
The document is a report from Haskell Laboratory regarding a skin irritation study involving textile fibers treated with a substance, indicating potential irritation and sensitization risks for PFOA when applied to human skin, suggesting further testing before commercialization. AR226-2858 r6yL792yK1d34x3MbYaYM277 1
The document reports on a mutagenicity assay conducted by E. I. du Pont de Nemours and Company at the Haskell Laboratory, testing a perfluorinated compound using the Salmonella/microsome assay to evaluate its potential toxicity. AR226-2859 rXdmQXaYKLnRdG4oQKG2bwer 4
This document is a laboratory report from DuPont's Haskell Laboratory detailing skin irritation and sensitization tests conducted on guinea pigs using a substance, likely related to PFOA or PFOS, with results indicating no significant irritation or sensitization responses observed in the test subjects. AR226-2862 xzpDb7poO0ZQDZDbG8ExdpoD0 2
The document is a report from E. I. du Pont de Nemours and Company detailing an eye irritation test conducted on rabbits using Haskell No. I1336, which showed no significant ocular effects on the cornea and mild conjunctival redness and discharge after treatment. AR226-2861 omo5gr7gJvYy2nR97OJ7EYvXR 2
This document reports on an acute oral toxicity test conducted by Du Pont de Nemours and Company on a substance, likely PFOA, indicating that lethal doses resulted in lethargy and prostration, with an approximate lethal dose (ALD) greater than 350 mg/kg. AR226-2863 mBe8Mj1YYEedj32gm7DLBq6NB 3
The document reports that the oral toxicity study of a substance, likely PFOA, administered to young adult ChR-CD male rats resulted in an LD50 greater than 25,000 mg/kg, with observed clinical signs of prostration and weight loss. AR226-2864 85KkjNzjQ5K99gG6wqxq1wv1B 1
The document reports on acute oral toxicity tests of a substance (unspecified) conducted by IFREB on rats, indicating no toxicological risk (LD50 > 20 g/kg), and tolerance tests on rabbits showing the substance as an ocular irritant but non-irritant for primary cutaneous irritation. AR226-2856 LeXN0RdGwge4Zr7p7D75gQNw 48
The document reports on an oral LD50 toxicity test conducted by E. I. du Pont de Nemours and Company on a test material, revealing that the LD50 value for the substance was determined to be 13,792 mg/kg based on mortality data from young adult ChR-CD male rats. AR226-2866 ExBZ1MV6Lww11VN5yoDyBQ9dV 3
The document reports on an eye irritation test conducted on rabbits using a waxy test material submitted by E. I. du Pont de Nemours Company, indicating that the material caused only transient mild conjunctivitis with no lasting ocular effects. AR226-2869 LpdVy30ooXn5V5qRap9Z5GJrX 2
The document reports on a primary irritation and sensitization test conducted by E. I. du Pont de Nemours and Company on a test material, likely related to perfluorinated compounds, using guinea pigs to assess skin reactions, with results indicating no significant irritation or sensitization responses. AR226-2870 bBrY6rxDMGqDKmRnBExdx4bwD 2
This is a Haskell Laboratory report (No. 422-78) from du Pont de Nemours and Company detailing a skin irritation test conducted on rabbits, with results indicating no irritation. AR226-2871 8VOZb2LJj99gyb0r0x69p8oZZ 1
The document reports on a subacute oral toxicity test of PFOA conducted by E. I. du Pont de Nemours and Company, indicating significant pathological changes in the liver, spleen, and thymus of male ChR-CD rats, along with notable weight loss compared to the control group. AR226-2873 44JNmn1GbVzEVpvQ3J2kNOZgQ 7
The document reports on a study conducted by Haskell Laboratory where PFOA was administered orally to young adult ChR-CD male rats at a dosage of 5,000 mg/kg/day for ten days, resulting in clinical signs of toxicity including alopecia, weight loss, and necrosis of various tissues, with some effects expected to be reversible after a recovery period. AR226-2874 zzLG9vNp1LyddKGL6K2806BRz 2
The document is a revised report from Haskell Laboratory detailing a study on the effects of an aqueous solution of a perfluorinated compound administered at a dosage of 3,400 mg/kg/day to young adult ChR-CD male rats, which resulted in liver hypertrophy and weight changes, indicating potential reversibility of the effects with a longer recovery period. AR226-2875 yrnRaaB35oGapx0JLq3ZE91eD 6
The document reports on a series of oral subacute toxicity tests conducted on male ChR-CD rats using a 50% suspension of a perfluorinated compound, resulting in high mortality rates among test subjects at dosages of 3,400 mg/kg/day and 1,700 mg/kg/day. AR226-2876 7Me8zxNBjL6d8KwBOm9p0Zzq8 4
The document reports on primary skin irritation and sensitization tests conducted on guinea pigs using a 20% solution of a test material, which was found to cause no skin irritation or sensitization responses. AR226-2878 MJrB2GQLE1jze88MX4kyaB0RV 2
The document is a laboratory report from E. I. du Pont de Nemours and Company detailing an oral LD50 toxicity test of a perfluorinated compound, indicating very low toxicity in young adult ChR-CD male rats with an LD50 value of approximately 5,043 mg/kg, and noting various clinical signs observed at different dosage levels. AR226-2879 7RkpdKjqmeRzmboLzjv09ENej 2
The document reports on an eye irritation test conducted by Haskell Laboratory for Du Pont de Nemours and Company, which found that a 2% solution of an unspecified perfluorinated compound caused very slight conjunctival irritation in rabbits, with no corneal effects observed. AR226-2880 d9Z5bnmYoj7jxv8w9D9ej9X9 2
The document reports on an oral LD50 toxicity test of PFOA conducted by Du Pont's Haskell Laboratory, indicating that high doses resulted in significant mortality and clinical signs of distress in rats within a few days post-dosing. AR226-2881 MM2e7wo4OzDDRX2RyBNDaqOLL 2
The document is a laboratory report from DuPont's Haskell Laboratory detailing an eye irritation test conducted on rabbits using Haskell No. 13,197, which resulted in slight corneal opacity and mild conjunctivitis, with recommendations for flushing the eyes with copious amounts of water. AR226-2882 0kR60x4n6MG7VLwMLNgrLVxx 3
The document reports that E. I. du Pont de Nemours and Company's material tested for skin irritation and sensitization on guinea pigs showed no irritation or sensitization responses, indicating a low dermatitis hazard from handling the substance. AR226-2883 Gm9qXonebB3Xv5Oj49pM5ZpJv 2
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the inhalation median lethal concentration (LC50) of a test material, likely a perfluorinated compound, using ChR-CDG rats exposed to vapor atmospheres. AR226-2884 wg2ZDmyeyra82d0EdMajGZKoJ 3
The document reports a skin irritation test on rabbits using an unspecified test material, indicating that it caused mild to slight skin irritation after 24 hours and mild to no irritation after 48 hours, suggesting good industrial hygiene practices in case of skin contact. AR226-2885 zopLdzK9oKKpgG4rL1DyMo6dg 2
The document reports on a skin irritation test conducted by E. I. du Pont de Nemours and Company on male albino rabbits using an undiluted test material, which resulted in slight erythema after 24 hours but no irritation observed at 48 hours, suggesting minimal skin irritation potential. AR226-2886 rBVjzXoEqErJ7jxZDB1p3y2Be 2
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company using undiluted test material on rabbits, finding it to be a mild ocular irritant with transient effects that resolved within one to two days. AR226-2887 Yjn1g5a7VrdwdONORGERgLokE 2
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company using a solid test material, which caused mild conjunctivitis in rabbits, indicating it is a mild eye irritant that should be flushed with water if contact occurs. AR226-2888 3J2Yx8BxGBQ8GanGKJ4MKLyMO 2
The document reports on an acute oral toxicity study conducted by E. I. du Pont de Nemours and Company on an unspecified perfluorinated compound, revealing that the lethal dose in rats exceeds 25,000 mg/kg with only slight weight loss observed at the highest doses. AR226-2889 LKZvpQL8wOr7yYKvk5ngdMbK5 2
The document is a report from E. I. du Pont de Nemours and Company detailing an eye irritation test conducted on rabbits using an undiluted test material, which resulted in mild ocular effects and severe discharge in the unwashed eye, with recovery observed within a few days. AR226-2891 MGNj3m44rQeXvOMYYXrkgRbYL 3
The document reports on a primary skin irritation and sensitization test conducted by E. I. du Pont de Nemours and Company on guinea pigs, indicating that the test material was a skin irritant at a concentration of 25% in distilled water, while showing mild to no irritation at 2.5%. AR226-2892 jLaBrwgd7YNmYQz8rkBXymNy 3
The document is a Haskell Laboratory report detailing an LD50 toxicity test of a perfluorinated compound conducted by du Pont de Nemours and Company, which found that the compound has an LD50 greater than 25,000 mg/kg, indicating very low toxicity when administered orally to rats. AR226-2893 2Dp6a1JbBOoyYRd3pMV8GeJ6 2
The document details a study conducted by Haskell Laboratory for Toxicology and Industrial Medicine to determine the 4-hour inhalation median lethal concentration (LC50) of a perfluorinated compound in male albino Crl:CD rats, specifically focusing on the exposure and analytical methods used during the investigation. AR226-2890 44r2ZJjayjrJ4MK9gRybVJEpR 3
This document details a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal concentration (ALC) of perfluorinated compounds in male Crl:CD rats, focusing on the effects of different process temperatures on toxicity. AR226-2895 5O92DE5Gq12xpYmdKeK2qO7e 4
The document reports on a skin irritation test conducted by E.I. du Pont de Nemours and Company on New Zealand White rabbits, which found no significant erythema or edema after the application of a PFOA-containing aqueous paste. AR226-2896 zdyYoLwLOaNwOOb2pdn0YnEnn 2
The document is a subacute inhalation toxicity study conducted by E. I. du Pont de Nemours and Company at the Haskell Laboratory, which tested the effects of repeated inhalation exposure to a specific perfluorinated compound (PFC) vapor on male rats, with exposure concentrations of 1.0 mg/l and 10.0 mg/l over a two-week period. AR226-2894 jy4zD8gE5JQDbOvnjvk9kBb1O 15
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company using a solid test material, which caused mild to moderate ocular effects, including corneal clouding and conjunctivitis, in both treated rabbits, with both eyes returning to normal after 14 days. AR226-2897 VJm092O5jmJ44ZnLQ488LN1pw 3
The document reports on an oral LD50 toxicity test for a perfluorinated compound conducted by E. I. du Pont de Nemours and Company, indicating that the substance is moderately toxic with an LD50 value of 2,196 mg/kg in young adult male rats, with various clinical signs of toxicity observed at different dose levels. AR226-2899 zQwV8e4MwroxZXoO3mQnqd8k7 3
The Haskell Laboratory report indicates that the material H-14,008, tested by E. I. du Pont de Nemours and Company, exhibited low acute toxicity to fathead minnows (Pimephales promelas) during a 96-hour LC50 study. AR226-2900 YpLG3wVBJjV9j1z5aoxYjBOV 4
This document outlines a desk study commissioned by the Dutch Ministry of Transport, Public Works, and Water Management, focusing on the environmental behavior, ecotoxicology, and usage of perfluorinated surfactants (PFS), including PFOA and PFOS, in the Netherlands. AR226-2686 VGgQJGbqXZMpZLZYar9NQ5pqg 12
The document discusses the Telomer Research Program's investigation into the biodegradation potential of 8-2 Telomer B Alcohol, a fluorotelomer intermediate, highlighting its physical-chemical properties and the challenges in testing due to its low water solubility and volatility, while also detailing the preparation of radiolabeled compounds for further studies. AR226-2689 KGx78XqoGpn3Y8meKBYOEMyXx 3
The document is a final report from DuPont detailing an Activated Sludge Respiration Inhibition Test of Telomer B 8-2 Alcohol, conducted in compliance with OECD guidelines, to assess its environmental impact. AR226-2687 2jbmvdQb1EvgZ1B7grBJ7mQy7 28
The document summarizes the screening studies for the biodegradability assessment of 8-2 Telomer B Alcohol, focusing on the challenges of low water solubility and adsorption, and outlines the objectives and methodologies of the Ready Biodegradation and Accelerated Biodegradation tests to identify critical parameters before longer-term studies. AR226-2690 pBVqvVKZ1npDMMkdyOnY912ra 4
This is a biodegradation study report (Revision 1) prepared by Pace Analytical Services for 3M, focusing on the biodegradation screening of telomer-type alcohols, with project initiation in August 2000 and completion in September 2001. AR226-2688 LpXmdXqga4Q43a212ExXMqVwd 39
The document outlines a biodegradability study aimed at assessing the potential transformation of telomer-based polymeric products into PFOA during sewage treatment, while addressing the presence of PFOA as an impurity and detailing the testing protocols to be used. AR226-2695 kmjY968v0RBO2v03yrXwyjw7J 4
The document is a report from DuPont detailing the results of a study on the ready biodegradation of 8-2 Telomer B Alcohol, conducted according to the OECD 301D Closed Bottle Test guidelines, completed on March 20, 2003. AR226-2692 EvqNEEmepVMeLg4KxZyJmr85V 29
The document is a report by DuPont detailing the aqueous stability of 8-2 Telomer B Alcohol as a function of pH, conducted under the Telomers Research Program sponsored by The Rand Corporation. AR226-2693 2qnGjZLMyRYL3Jo1XM553oL35 32
The document is a report by E.I. du Pont de Nemours and Company detailing a preliminary screening study on the accelerated biodegradation of 8-2 Telomer B Alcohol, conducted under OECD guidelines. AR226-2691 jBJRbpLDN37wGy4ejZejxEYdQ 48
The document reports an oral LD50 toxicity test for a perfluorinated compound conducted by E. I. du Pont de Nemours and Company, indicating that the compound has a low toxicity with an LD50 value of 7,797 mg/kg in young adult Crl:CD male rats, with observed clinical signs including weakness and weight loss. AR226-2901 ykoja9nBg0eDrqwOQr6MjqE4n 3
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the inhalation median lethal concentration (LC50) of a test material, revealing that no deaths occurred in male albino rats exposed to atmospheric concentrations as high as 9.6 mg/L. AR226-2902 RpKwM6mZaNoa9dv8xRwyxDjpn 3
This document reports on a study conducted by E. I. du Pont de Nemours and Company to assess the inhalation toxicity of a substance (likely a perfluorinated compound) in male rats, determining an LC50 value of 35.3 mg/L after repeated exposure. AR226-2903 re5Gobrk6m87weKrVwpeQ2NKq 14
The document reports an oral LD50 toxicity test for PFOA conducted by E. I. du Pont de Nemours and Company, revealing that the LD50 value in young adult male rats is approximately 916 mg/kg, with various clinical signs observed at different dosage levels. AR226-2905 wqYzOMadb2587VBQO01Ro2mJ3 2
The document is a Haskell Laboratory report evaluating the ocular irritancy potential of a chemical, focusing on sources of intralaboratory variability and the effect of dosage volume, with findings indicating significant variability in results from standardized tests. AR226-2904 O15zvKG40JyQRQ0rO437ywjLv 17