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This document is a letter from Taft, Stettinius & Hollister LLP addressing the U.S. EPA regarding human health threats from releases of PFOA/APFO/C-8 in West Virginia and Ohio, serving as a supplement to a previous correspondence on the same topic.
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2007 |
AR226-1307
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5LmwL2qK3MaO2DKamGEw2LZQ5 |
3 |
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The document is a report from the Epidemiology Program detailing cancer incidence data from 1959 to 2001 at the DuPont Washington Works site in Parkersburg, West Virginia, comparing observed cancer cases to expected cases using the Standardized Incidence Ratio (SIR).
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2003 |
AR226-1307
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Lp2yJJV9Zavo2GGeB6kZDGBeb |
19 |
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The document summarizes a two-generation reproduction study of Ammonium Perfluorooctanoate (APFO) in rats conducted by 3M, indicating that while parental animals showed more severe effects than offspring, there were suggestive reproductive effects such as decreased pup weights and altered estrous cyclicity at a dose of 30 mg/kg/day, leading DuPont to conclude that APFO is not
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2002 |
AR226-1307
|
jyE0EXBdq7eVXX3mDw4j0OKL2 |
10 |
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The document reports on a study of 51 employees with the highest blood levels of C-8 (perfluorooctanoic acid), indicating minimal evidence of disease attributable to C-8, with some elevations in liver enzymes and a few cases of kidney disease, but no definitive conclusions due to lack of controlled studies.
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1996 |
AR226-1307
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jyvkNYO19w9nq8qn87EMMQ2B2 |
6 |
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The document discusses a study by 3-M indicating that ammonium perfluorooctanoate (C-8 compound) used in Teflon manufacture causes eye scarring in rat fetuses following maternal exposure, prompting concerns about potential risks for female employees at Parkersburg and other locations, while questioning the study's validity.
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1981 |
AR226-1307
|
rBn1JNQpQppZ0LN26vOdjod30 |
2 |
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This is a letterhead cover page from an unspecified organization, with no analytical content retained in the OCR.
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— |
AR226-1307
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k9XBLjngbOv0zmO5Nd2qLRXpB |
4 |
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The document is a confidential epidemiology surveillance report by DuPont detailing cancer incidence and mortality among employees at the Washington Works facility from 1956 to 1993, comparing observed cases and deaths to expected rates.
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— |
AR226-1307
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7O0NqOzngdZa5eedYdppMgvkR |
15 |