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CD 14 — AR226-1068a

EPA administrative record segment: CD-14--AR226-1068a (1,777 documents).

Page 8 of 18 — 1,777 documents
Title / Summary Year AR226 Docket Hash ID Pages
The document reports on a developmental toxicity study of N-EtFOSE (N-Ethyl-Perfluoroocyanesulfonamido Ethanol) in pregnant rabbits, finding that while there were dose-related effects on body weight and food consumption at higher doses, the compound was not teratogenic, with no malformations observed in the fetuses. 1999 AR226-0274 NEjaz5k3X2LGwj6pbMkeNDBQR 1
The document outlines a protocol for a study on N-EtFOSE bile method development in rats, conducted by 3M's Corporate Toxicology department, to support an ongoing ADME study in Cynomolgus monkeys. 1999 AR226-0288 e1MLVwd7QOrqgV1j6VoeoDpbE 7
The document outlines a study protocol by 3M to assess cell proliferation and peroxisome proliferation in rats administered N-Ethyl Perfluorooctanesulfonamido Ethanol (N-EtFOSE), Perfluorooctane Sulfonic Acid Potassium Salt (PFOS), and N-Ethyl Perfluorooctanesulfonamide (PFOSA 1999 AR226-0290 4nXb791wJB75kD6n6oE4OLKG 14
The document discusses concerns regarding the finalization of a toxicity study report on N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE) conducted by Covance Laboratories, specifically questioning the conclusion of a no observable adverse effect level (NOAEL) of less than 3 ppm based on body weight gain data in rats. 1999 AR226-0301 Qg5b60L9OQmqb6w4q1vqwJdGL 1
This is a Quality Assurance Project Plan for the Multi-City Study Sampling Task (N10Q666) prepared by Battelle, effective May 14, 1999, detailing project management, quality assurance objectives, and sampling methodologies. 1999 AR226-0952 6BmzJyy2Z9844pegr01kOMkk6 52
The document outlines a study protocol sponsored by 3M to assess cell proliferation and peroxisome proliferation in rats administered N-Ethyl Perfluorooctanesulfonamido Ethanol (N-EtFOSE), Perfluorooctane Sulfonic Acid Potassium Salt (PFOS), and N-Ethyl Perfluoroctanesulfonamide (PFOSA 1999 AR226-0332 bKmgwba41n09NORzqnZrYae3 14
This document reports on a dietary LC50 study of PFOS conducted by Wildlife International Ltd. for 3M Corporation, which was completed on April 26, 2000, and indicates that the study was performed in compliance with Good Laboratory Practice standards, although some aspects of substance characterization did not fully adhere to GLP compliance. 1999 AR226-0953 jjbnBv6aJmg8qbEewGg4RX9 83
The document reports on a developmental toxicity study of PFOS (Perfluorooctanesulfonate) conducted on pregnant rabbits, indicating that while there were dose-related effects on body weight and food consumption at higher doses, no teratogenic malformations were observed. 1999 AR226-0949 VGOO9mVxV6wMb1e5gGrLYEg0N 295
The document reports the melting point determination of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), indicating a melting point range of 55°C to 60°C, suggesting the presence of impurities in the sample. 1999 AR226-0347 B5Xqyvbx438zXKaXRwdpgEyQ4 3
The document is a laboratory report from 3M Environmental Technology and Services detailing pilot data on perfluorooctanesulfonate (PFOS) concentrations in a limited number of pediatric serum samples, indicating that while concentrations were above detection limits, no conclusions can be drawn due to the small sample size, with plans for a larger study involving over 600 samples. 1999 AR226-0961 v1oMdLBnb1L3X5L0vgVxM8d2Y 66
The document reports on a stability study of N-methylperfluorooctanesulfonamido-ethyl acrylate (MeFOSEA), revealing that its hydrolysis half-lives vary with pH and temperature, with longer half-lives observed at lower temperatures and higher pH levels. 1999 AR226-0380 VZM6N2NY5gYL2VJdmXOMzqzZ 70
The document is a final report on a developmental toxicity study of N-EtFOSE conducted in rabbits, detailing methods, results, and conclusions regarding the substance's effects. 1999 AR226-0967 4aqB4wKZeo1pOdDnB46LEkv4j 318
3M submitted a TSCA Section 8(e) supplemental notice to the EPA detailing refined analyses of human sera samples that confirmed the presence of perfluorooctane sulfonate (PFOS) and detected additional perfluorinated sulfonates (PFS) and perfluorinated carboxylic acids (PFCAs). 1999 AR226-0540 a1aVBxoZB3qg6KkgKoQy4XmLX 3
The document reports on a cross-fostering study of PFOS (perfluorooctanesulfonate) conducted by 3M, detailing the study's methodology, findings related to toxicity, and the purity of the PFOS used, with results analyzed between July 1999 and February 2000. 1999 AR226-0556 d2pEO1MZ3yZaZnoQmgw9erDb 9
This is a final report for Protocol 418-009 detailing a combined oral fertility, developmental, and perinatal/postnatal reproduction toxicity study of N-EtFOSE in rats, with the sponsor's study number 6316.5, dated June 30, 1999. 1999 AR226-0552 3ejo0jpvgZaoDXMM8d1ewOmYD 243
The Tennant Farm Herd Health Investigation report, prepared by the EPA/DuPont Cattle Team, evaluates the health of cattle on the farm, identifying issues such as malnutrition and toxicology concerns, but does not specifically mention PFOA or PFOS. 1999 AR226-1243 3QLmJm4yR82NZZ2ZnkxG3dBQJ 121
This document is an amended report of a dietary LC50 study on PFOS conducted with mallards by Wildlife International Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practice standards despite some exceptions noted regarding substance characterization and stability analysis. 1999 AR226-1735 9bKr7KMmJrmRmXVmvaqGKy35 72
This document reports on a dietary LC50 study of PFOS conducted on the Northern Bobwhite by Wildlife International Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practice standards despite some exceptions regarding the characterization of the test substance. 1999 AR226-1747 0Lz49r41qpxq2wDKJojr5Lpvm 69
The document outlines a corporate toxicology study conducted by 3M on FC-129, focusing on its absorption, distribution, metabolism, and excretion (ADME) in rats, with the objective of identifying persistent metabolites. 1998 AR226-0227 peEE4jgaoOE6g9GgLgVnqnxxD 1
The document provides an overview of 3M's production of perfluorooctanesulfonyl fluoride (POSF) using the Simons Electro-Chemical Fluorination process, detailing the synthesis method and the chemical's identification. 1998 AR226-0576 wJLGbzEGnyzB5ywkRBX98KBV 25
The document provides information about N-Methyl perfluorooctanesulfonamide (MeFOSA), produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its chemical identification, production methods, and distribution estimates. 1998 AR226-0581 QxOREoDdm0XzakX7jMkB6aL6 20
The document provides information about N-Ethylperfluorooctylsulfonamido ethanol (EtFOSE), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis and distribution estimates. 1998 AR226-0582 XzJJyyVm1kRrmne2nkOaxL0dw 24
The document provides information about N-ethyl perfluorooctanesulfonamido ethyl methacrylate (EtFOSEMA), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis and characteristics. 1998 AR226-0585 rx5Gy6aR63a2KMK33Dk88BERq 20
The document provides information about N-Methyl perfluorooctanesulfonamidoethyl acrylate (MeFOSEA), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis and distribution estimates. 1998 AR226-0586 EdXydwzzvQ3M8zKQNLa0dwx8L 25
The document is a meeting request from 3M to the EPA, discussing the company's position on the safety of PFOS levels in human and environmental contexts, asserting that current data do not indicate significant health risks associated with PFOS. 1998 AR226-0621 jmE68mq5O5V4Qq6DN1Nej77Z9 2
This letter from 3M outlines action items agreed upon with the EPA regarding the development of a product stewardship agreement and the provision of health effects information and exposure assessments related to perfluorooctane sulfonic acid (PFOS). 1998 AR226-0624 ZBVVV0n8x1O4ODp0nMmK4xgk7 1
This document is a pathology review assessing tumorigenesis data from a two-year study on the fluorochemical FM-3924, sponsored by 3M, to evaluate its chronic toxicity and carcinogenic potential in rats. 1998 AR226-0264 b5VY6E88Gqv71xzR05eBqB101 7
The document outlines a protocol for determining the melting point/melting range of PFOS (perfluorooctane sulfonic acid, potassium salt) to be conducted by Wildlife International Ltd. for 3M Corporation, following OECD testing guidelines. 1998 AR226-0046 rpdGpJL0OZ3OzKa2D8JOwv6MJ 9
The document reports on a study conducted by Wildlife International Ltd. to determine the melting point/melting range of PFOS, sponsored by 3M Corporation, in compliance with Good Laboratory Practice standards. 1998 AR226-0045 rBOaEJaRx4n9m7kbmO1j4KOMV 14
The document outlines a protocol for determining the vapor pressure of PFOS (perfluorooctane sulfonic acid, potassium salt) using the spinning rotor gauge method, to be conducted by Wildlife International Ltd. for 3M Corporation in accordance with OECD testing guidelines. 1998 AR226-0049 2Rzq6D9VqBeGDpJe6DvYpEdZN 9
The document outlines a protocol for determining the water solubility of PFOS (perfluorooctane sulfonic acid, potassium salt) using the shake flask method, as requested by 3M Corporation and conducted by Wildlife International Ltd. 1998 AR226-0053 MJO3exyg2Eekw59b5qxZDwMpk 10
The document is a final pilot report on an oral dosage-range developmental toxicity study of N-EtFOSE conducted in rats by Argus Research Laboratories, detailing the study's purpose, methods, results, and conclusions. 1998 AR226-0272 kDma3byrBzyvjd1jgXbg0ELpE 112
The document is a final report on a 96-hour static acute toxicity test of PFOS conducted on fathead minnows (Pimephales promelas) by Wildlife International Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practice standards despite some exceptions in substance characterization and stability determination. 1998 AR226-0083 v69x85ZDk9NVv7JRbqLN98dB8 58
The document is an amended final report of a 48-hour static acute toxicity test conducted by Wildlife International Ltd. on PFOS using the cladoceran Daphnia magna, sponsored by 3M Corporation, and completed on June 4, 1999, with compliance to Good Laboratory Practice standards. 1998 AR226-0087 Bvvwx91vZ2N6MdmzwLMgavVo4 55
This document is an amended final report of a 96-hour toxicity test conducted by Wildlife International Ltd. on PFOS using the freshwater alga Selenastrum capricomutum, sponsored by 3M Corporation, and it outlines compliance with Good Laboratory Practice standards. 1998 AR226-0085 aJbpMM1dDaDJK4GR5nX96872b 75
This final report details an activated sludge respiration inhibition test conducted by Wildlife International Ltd. for 3M Corporation, assessing the effects of PFOS, with noted deviations from Good Laboratory Practice compliance regarding substance characterization and stability. 1998 AR226-0093 Lgr7q3k4mGeyRoyYqDam3xyKz 63
The document details a toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) using the marine algal species Skeletonema costatum, indicating that the test sample, FC-201AF, consists of 3% PFOS among other components, and outlines the methodology and conditions for assessing algal growth inhibition. 1998 AR226-0695 9Qe3R24wBVvzLqrzoZ0Lqrkq 34
The document discusses the rationale for dose setting in a six-month chronic oral study of PFOS in Cynomolgus monkeys, highlighting a linear relationship between cumulative dose and serum concentration, with recommended dose groups of 0.0, 0.02, 0.15, and 0.75 mg/kg/day. 1998 AR226-0147 wrenRLD1Z2LOOjqy1VdoLL1aE 13
The document is an unaudited draft final report of a 4-week capsule toxicity study on Perfluorooctane Sulfonic Acid Potassium Salt (PFOS) conducted by Covance Laboratories for 3M, adhering to EPA Good Laboratory Practice Standards. 1998 AR226-0144 jgv6kGJKm0ZgERoDp1MrjqV4O 230
The document details a toxicity test of a mixture containing 1.34% PFOS, conducted using the marine algal species Skeletonema costatum, to assess its impact on algal growth over a 72-hour exposure period. 1998 AR226-0732 ypkm7RV9LOGDaOokrmBq3w8OX 34
The document is an analytical report prepared for 3M Medical Department detailing the characterization of metabolites T-6292, T-6293, and T-6294 from rat and human hepatocytes, along with a semi-quantitative analysis of T-6295 using LC/MS and LC/MS/MS techniques. 1998 AR226-0163 82LRXawrwzr60j7jO8az6Nz6K 69
This is a cover page for a supplement of the journal "Toxicological Sciences," published by Academic Press in March 1998, containing various studies including those on particulate matter and coumarin's antitumor activities. 1998 AR226-0172 LJ3Z3xy6nkB2OQKQy651B97og 3
The document details a toxicity test of a mixture containing 1% PFOS, conducted using the marine algal species Skeletonema costatum to assess its impact on aquatic plants, following the NS-EN ISO 10253 method. 1998 AR226-0846 GmrqMrnBr4DaeKQNJvzrzk687 35
The document details a toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) using the marine algal species Skeletonema costatum, following the NS-EN ISO 10253 method, to assess its impact on algal growth. 1998 AR226-0859 6X6RXLked1kVGdp0dMrgYLv4 34
The document outlines a study by 3M Medical Department's Toxicology Services to investigate potential sources of low-level perfluorooctanesulfonate (PFOS) contamination in control rats, including contamination from the housing area, feed, and background serum levels, with various study directors appointed for each objective. 1998 AR226-0960 XOL53M8VEoezqzeKQGjKkmYDG 24
The document reports on the estimated boiling point of N-Ethylperfluorooctanesulfonamide (EtFOSA), a substance produced by 3M Company, based on extrapolated data from a vapor pressure study, indicating a boiling point of approximately 423°C at 760 mm Hg. 1998 AR226-0334 by0g6ko53ppEyKG5qzvXNbQpo 4
The document reports on a vapor pressure study of N-Ethylperfluorooctanesulfonamide (EtFOSA), conducted by AScI Corporation for 3M Company, indicating a vapor pressure of 0.142 Pa at 20°C, with a noted concern regarding the accuracy of the sample's 99% purity. 1998 AR226-0335 jYxwDvYKbj2wperYdV9QoooQ 28
The document reports on an acute toxicity test of N-Ethylperfluorooctanesulfonamide (EtFOSA) on the fish species Pimphales promelas, detailing the test conditions and methods used, but does not provide specific results or findings. 1998 AR226-0337 vBKpxn30ZppqdDegJaD5pznrw 10
The document reports on an acute toxicity study of N-Ethylperfluorooctanesulfonamide (EtFOSA) on Daphnia magna, detailing the test conditions, methods, and nominal loading concentrations used to assess lethal loading values. 1998 AR226-0338 baKn03Logp65eMaypNzK589Z1 9
The document reports on an acute toxicity test of N-Ethylperfluorooctanesulfonamide (EtFOSA) on the aquatic invertebrate Ceriodaphnia dubia, detailing the test conditions and methodology used to determine lethal loading values. 1998 AR226-0340 1gVm9B0MVgGzG1nzLOdbE1baK 9
The document details an activated sludge respiration inhibition test conducted on N-Ethylperfluorooctanesulfonamide (EtFOSA) to assess its impact on dissolved oxygen concentrations, using activated sludge from Duluth, MN, with results indicating the substance's effects on respiration rates. 1998 AR226-0342 xz58zgVGyo6OrRjG27jeON5YQ 9
The document reports the boiling point determination of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol) as part of a vapor pressure study conducted by 3M Company in 1998, noting that the boiling point values were extrapolated rather than empirically obtained. 1998 AR226-0345 LgB2DXnr7dGwnaQ55VDNo4bJz 4
The document reports on a vapor pressure study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), indicating that it is a stable white waxy solid with a vapor pressure suggesting it would primarily exist in the gas phase in the atmosphere, despite some concerns regarding the purity and data variability. 1998 AR226-0346 Ex13VNk1pv9XY8VME5GRYy0GL 62
This document is a final report of a two-generation reproduction study on ammonium perfluorooctanoate (APFO) conducted in rats by Argus Research, sponsored by a company, and completed on March 26, 2002, adhering to EPA Good Laboratory Practice standards with noted exceptions. 1998 AR226-1092 VG9v2MXwmwmV6zqaRznoLR6nq 1245
This is a final report on a developmental toxicity study of N-EtFOSE in rats (Sponsor's Study Number: T-6316.7) conducted under Protocol 418-011, dated December 17, 1998. 1998 AR226-0966 yk5nkyG3D8qv4aEqpErwonGQV 163
This document outlines a protocol for a 26-week toxicity study of Ammonium Perfluorooctanoate (APFO) in cynomolgus monkeys, sponsored by the APME Ad-Hoc APFO Toxicology Working Group, to evaluate its effects on enzyme levels, hormones, and biochemical parameters. 1998 AR226-0452 pmvreXv2dLYzkJ2q7mBaVE6jD 18
The document discusses a review of teratology studies on FC 95 and FC 143, concluding that an eye lens defect reported in the original FC 95 rat study was a sectioning artifact and that no teratogenic effects were observed at non-maternally toxic doses, with further teratology studies planned for both compounds. 1998 AR226-0468 pmR679N4o8DkOzBoGGNBxpr1D 3
This document summarizes a study by Olsen et al. that investigated the association between serum levels of perfluorooctanoic acid (PFOA) and reproductive hormone changes in male production workers at 3M, finding no significant correlation with estradiol or testosterone levels, although a confounded increase in estradiol was noted among those with the highest PFOA levels. 1998 AR226-0474 jBgK4oXOKNLE9md01ZvDJM5zQ 10
The document is a final report from 3M Company detailing an epidemiologic investigation into the effects of perfluorooctanoic acid (PFOA) on plasma cholecystokinin levels and hepatic function among PFOA production workers, finding no positive association between serum PFOA levels and clinical hepatic toxicity. 1998 AR226-0477 wr9n37rNpzOnxdZJ9b7NayDnB 67
This document reports on a 90-day oral gavage study conducted by DuPont to assess the subchronic toxicity of Telomer B Alcohol in rats, adhering to U.S. EPA Health Effects Test Guidelines. 1998 AR226-1342 jybgvygEO5KzjJXXNgvaVNO6y 967
This document appears to be a data collection form for deer reproduction analysis, detailing information such as the identification number, data collector, date of collection, cause of death, and various measurements and characteristics of the fetuses and doe. 1998 AR226-1241 J3zo7JppD70BwQBM6o9YgqzvB 26
The document reports on a study titled "Perfluorooctanoic Acid: Toxicokinetics in the Rat," conducted by E.I. du Pont de Nemours and Company under Good Laboratory Practice standards, sponsored by the Association of Plastics Manufacturers of Europe, focusing on the metabolism and pharmacokinetics of PFOA. 1998 AR226-1499 15vrawvX94bKL4myZVq2vEzba 212
The document details a 19F-NMR spectral analysis conducted by 3M Specialty Adhesives & Chemicals to determine the identities and relative concentrations of fluorochemical isomers and impurities in the sample FC-95, lot # 217, revealing specific compositional results. 1997 AR226-0564 N2ygYDMejXNrv21rJZor8Kzn8 2
The document provides information on the chemical identification and synthesis process of Perfluorooctane sulfonamido ethyl acetate (PFOSSA), including details about its production by 3M Company using the Simons Electro-Chemical Fluorination process. 1997 AR226-0578 DM2wJRrV01KBKxv53mYX7Ra4Q 13
The document provides information on the voluntary use and exposure profile of Perfluorodecane sulfonate (PDSF), including its chemical identification, manufacturing process by 3M Company, and details about its production and distribution. 1997 AR226-0579 nmnD4MmbmagqDQZ2GXryv4R0w 12
The document provides information on N-ethyl perfluorooctanesulfonamide (EtFOSA), including its production by 3M Company using the Simons Electro-Chemical Fluorination process, with an estimated off-site distribution of 59% of the less than 100,000 lbs manufactured. 1997 AR226-0580 2JRp4pxMvxMqpV6pG07vB7b0L 23
The document provides information on N-methyl perfluorooctanesulfonamido ethanol (MeFOSE), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis, production volume, and distribution estimates. 1997 AR226-0583 0gwNV9XkMBQ4EV3ydQxX18Krd 23
The document details an acute toxicity test of a mixture containing 3% perfluorooctanesulfonate (PFOS) on the marine copepod Acartia tonsa, using ISO/DIS 14669-1997 methodology to assess lethal effects over a 48-hour exposure period. 1997 AR226-0696 B8BxYYK8Bbk56dR2rvOEG89mk 34
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on the marine copepod Acartia tonsa, indicating that the test sample, FC-203, comprises 1.34% PFOS along with various other components, and outlines the methodology used for assessing toxicity. 1997 AR226-0731 k6G38RJ25opb5Gjd0bGbm584V 34
This document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company, indicating that the chemical oxygen demand (COD) and biochemical oxygen demand (CBOD) values were measured, but the study lacks analytical confirmation of the sample's purity and the fluorochemical proportion. 1997 AR226-0768 8V1z3jvYjxLRZq7dejyLYL3ey 6
The document details a Microbics Microtox toxicity test conducted on a mixture containing 0.85% PFOS, indicating that the test sample, FC-203FC, was evaluated for its toxic effects on the organism Photobacterium phosphoreum, although the data may not accurately reflect the toxicity of the fluorochemical component due to incompletely characterized impurities. 1997 AR226-0769 BRKX7G3o2GnORjbQeQK029Kd4 9
The document details an activated sludge respiration inhibition test conducted on a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test was performed according to OECD Guideline 209 to assess the toxicity of the fluorochemical component. 1997 AR226-0770 wgnB2RNpQYDeav3rqb38dG7NQ 10
The document details an acute toxicity test of a mixture containing 0.85% perfluorooctanesulfonate (PFOS) on Daphnia magna, conducted according to OECD Guideline 202, with results indicating potential toxicity but noting that data may not accurately reflect the toxicity of the fluorochemical component due to impurities. 1997 AR226-0771 67mBqzwaOy1Ne0eBm09MQ0b3 10
The document details a toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic plant species Selenastrum capricornutum, using OECD Guideline 201 methods to assess algal growth over a 96-hour exposure period. 1997 AR226-0772 kmnKoN69rbKdb0191nO7qBdvq 11
The document reports on an acute toxicity test of a mixture containing 0.85% PFOS (perfluorooctanesulfonate) conducted on fathead minnows (Pimephales promelas) using OECD Guideline 203, indicating that the test sample was a mixture with various other components and that the data may not accurately reflect the toxicity of PFOS alone. 1997 AR226-0773 nmMjXVjXkqRjR43pDX6o5gdn1 4
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on fathead minnows (Pimephales promelas), conducted according to OECD Guideline 203, with the test revealing that the mixture includes 0.85% PFOS among other components, although the data may not accurately reflect the toxicity of the PFOS itself due 1997 AR226-0774 77NMyx77mwGQQ15LK3reMKD6 10
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on the aquatic invertebrate Acartia tonsa, indicating that the test sample is FC-602, which comprises 1% PFOS among other components, and outlines the testing methodology and conditions used. 1997 AR226-0845 DMyLD77r3vaJJ58B59m1Qynko 35
This document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on fathead minnows (Pimephales promelas), conducted according to OECD Guideline 203, with results indicating the need for caution due to the presence of impurities that may affect toxicity assessment. 1997 AR226-0858 mpJYVqxpm2661bXRBDaY1o62Z 10
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the marine copepod Acartia tonsa, using ISO/DIS 14669-1997 methodology to determine lethal toxicity levels. 1997 AR226-0860 7MNpwov2a4KL6D7rb36BjYM5o 68
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but noting that the sample purity was not properly characterized. 1997 AR226-0882 aBMMQOjOV9ynm7v74DMax4byX 6
The document details a Microbios Microtox toxicity test conducted on a mixture containing 1% perfluorooctanesulfonate (PFOS) and various other components, indicating that the test was performed to assess the acute toxicity of the substance using Photobacterium phosphoreum as the test organism. 1997 AR226-0883 JrbOjQ5dmoQxVDpMy5zVQxqgv 9
The document details an activated sludge respiration inhibition test conducted on a mixture containing 1% PFOS, produced by 3M, indicating that the test sample's toxicity may not accurately reflect the fluorochemical component due to incompletely characterized concentrations of impurities. 1997 AR226-0884 EqkQkvOe8eXVX9oyRj4oemNyx 10
This document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on Daphnia magna, indicating that the test sample, identified as FC-3003, consists of 1% PFOS among other components, and was conducted under OECD Guideline 202 conditions. 1997 AR226-0885 b5owneZKXLxj3w96OzE7oG8n0 9
The document details a toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the algal species Selenastrum capricomutum, following OECD Guideline 201, to assess its effects on aquatic plants over a 96-hour exposure period. 1997 AR226-0886 3Na3E8RqNQyQEjBLYLOyMnqVn 11
The document details an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted by Aquatic Biosystems, Inc. on juvenile fathead minnows (Pimephales promelas) using OECD guidelines, with the test sample identified as FC-3003, which is composed of 1% PFOS among other components. 1997 AR226-0887 6bnEr63ZnV5vaqnr8d3a9KVbm 4
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1% perfluorooctanesulfonate (PFOS) and other components, following OECD Guideline 203, with results indicating the need for caution due to the presence of impurities that may affect toxicity assessment. 1997 AR226-0888 X8zY199a9qVbjn571zwmLxrKG 11
The document is a final report on a Primary Dermal Irritation/Corrosion study of T-6684, sponsored by 3M and conducted by Corning Hazleton Inc. in accordance with OECD guidelines, completed on January 10, 1997. 1997 AR226-0321 rebva6p0vNMDyNxkR1r1bkyNe 27
This document is a final report on a Primary Eye Irritation/Corrosion Study of T-6684, sponsored by 3M and conducted by Corning Hazleton Inc. in accordance with OECD guidelines, with a completion date of January 28, 1997. 1997 AR226-0322 7Ozz4NJ0JyBMbwBZ7p87Z7v4R 31
The document outlines the compliance and findings of Exygen Research's study, sponsored by 3M, which analyzed pooled human and monkey sera for fluorocarbons, including issues related to data retention, test item stability, and instrument qualification. 1997 AR226-1152 qmObe2OMnXEzOGn8Mz9x1Vqzk 110
This is a draft report prepared by Mark D. Sprenger, Ph.D., and Michael T. Horne, Ph.D., for the Environmental Response Team and U.S. Fish & Wildlife Service regarding the Dry Rum Creek site in Wood County, West Virginia, detailing methodologies and preliminary risk assessments related to environmental sampling and analysis. 1997 AR226-1240 B5m2qNqZxNzJDmKQjRr0nDg14 728
This document is a final report on an acute oral toxicity study of T-6669, a substance sponsored by 3M, conducted on rats in accordance with OECD guidelines, with the study completed on January 10, 1997. 1997 AR226-0420 v1pwEEe4p6xDaEKo70GgVzV9w 35
The document is a final report on a five-day oral toxicity study of the substance T-6669, sponsored by 3M, conducted on rats by Corning Hazleton, with a completion date of April 30, 1997. 1997 AR226-0451 dnXDm11byODve9DwqqOkz7nkG 90
The document is a final report of a single-dose intravenous pharmacokinetic study of T-6564, sponsored by 3M, conducted by Corning Hazleton Inc. on rabbits, with a completion date of April 18, 1997. 1997 AR226-0460 revGZzab4NZmakQn19dMpGbbJ 34
This is a final report from Corning Hazleton Inc. (Laboratory Project ID: CHW 6329-185) detailing a 5-Daily Dose Dermal Absorption/Toxicity Study of T-6564 in rabbits, sponsored by 3M, with a completion date of April 28, 1997. 1997 AR226-0461 a4rbnjRMGyJGrwR2znZ8LEEkX 49
This document reports on a study assessing plasma cholecystokinin levels and hepatic enzyme responses in 84 production workers exposed to perfluorooctanoic acid (PFOA) at 3M, finding no significant clinical hepatic toxicity or modulation of hepatic responses to obesity and alcohol consumption related to PFOA exposure. 1997 AR226-0476 D50J8oaaeX1LkpJLjk0EpKnB 25
The document reports on a biodegradation study of perfluorooctylsulfonate, a fluorochemical produced by 3M, indicating that some portion of the test sample biodegraded in aerobic environments, though it could not rule out the potential for further biodegradation under different conditions. 1997 AR226-0533 OLzqm20qavwdRneYg5EO6Qdj 10
The document details an activated sludge respiration inhibition test conducted on perfluorooctylsulfonate (PFOS) produced by 3M, indicating that the test sample was a mixture of the substance in water and outlining the methodology and conditions of the test. 1997 AR226-0539 mmJ5dRZoY1RN2G02ByL5a0YM4 9
The document reports on a study conducted by Dr. U. Noack-Laboratorium examining the effects of 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro on the development of Caenorhabditis elegans in a 1997 AR226-1431 zQREx5Zoj120jZDz0QNy7VaoB 20
The document is a final report from Hita Research Laboratories detailing a bacterial reverse mutation test of a substance (designated as u-1) sponsored by Sumitomo 3M Limited, conducted in compliance with Japanese toxicity investigation standards. 1996 AR226-0221 4ap6KnNQVgm60pmjj16Ob2rnG 23
The document is a final report on a mutagenicity test conducted by Corning Hazleton Inc. using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay to evaluate the mutagenic potential of a substance, with the study conducted in compliance with Good Laboratory Practice regulations. 1996 AR226-0232 J3VE76Nzmdx8xrEDDyNyxwpOB 30