|
The document details an activated sludge respiration inhibition test conducted on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), produced by 3M, indicating varying levels of inhibition in respiration rates at different concentrations.
|
1987 |
AR226-0510
|
8wMb4O93wR8Nj8QqxNkz859B |
7 |
|
The document presents the results of a Microtox toxicity test conducted by 3M on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), determining its 30-minute EC50 value for Photobacterium phosphoreum to be 870 mg/L.
|
1987 |
AR226-0511
|
g2R9pxKYBqj6zbN04pa6ZVB1a |
4 |
|
The document reports an acute toxicity test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) on Daphnia magna, conducted by 3M, which found a 48-hour EC50 value of 221 mg/L.
|
1987 |
AR226-0512
|
2RnqRk9e8zLB7rE0Q4xQKZeNb |
4 |
|
This document reports on an acute toxicity test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) conducted on the fish species Pimephales promelas, revealing total mortality at higher concentrations (320 mg/L and above) within 24 hours.
|
1987 |
AR226-0513
|
XRw301359pyw7wyqpKb6kKJad |
4 |
|
The document is a memo from DuPont requesting the establishment of acceptable levels for ammonium perfluorooctanoate (C-8) in blood and community drinking water.
|
1987 |
AR226-1636
|
jxwmwkROjzqJmdXYBL5M7odR |
1 |
|
The document reports that a primary skin irritation test conducted on T-3874 at Riker Laboratories, Inc. found it to be non-irritating to the skin of female albino rabbits, with no signs of erythema or edema observed.
|
1986 |
AR226-0205
|
MJwgQjXwL5aewGnJKb39L5y3y |
10 |
|
The document discusses the spreading kinetics of aqueous solutions of a mixture of hydrocarbon and fluorocarbon surfactants, specifically focusing on a commercial AFFF (aqueous film-forming foam) agent, and establishes an empirical relationship between the rate of spreading and various experimental parameters.
|
1986 |
AR226-1315
|
xjgK9yaDLBKgqGjodQz4Gdb7g |
10 |
|
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3752, which was found to be reproducibly non-mutagenic and non-recombinogenic in tests conducted according to FDA Good Laboratory Practice Standards.
|
1985 |
AR226-0247
|
RjYv18jQdzbQ2xJ9gd3x9Bd8B |
20 |
|
The document is a final report from Hazleton Laboratories America, Inc. detailing an acute oral toxicity study of the test material T-3727, which is associated with Minnesota Mining and Manufacturing Company, using Sprague-Dawley rats to assess its safety according to OECD guidelines.
|
1985 |
AR226-0245
|
R7KoLd46Yz7jamN7eMvVv14E |
102 |
|
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3727, which was found to be reproducibly non-mutagenic when tested using the standard Ames Salmonella/microsome assay.
|
1985 |
AR226-0248
|
RaeQKa0d1Vz7dXDqzXDparJKV |
16 |
|
The document is a final report from SRI International detailing the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3651, which was found to be nonmutagenic and nonrecombinogenic in the tested assays.
|
1985 |
AR226-0684
|
0qXng7qXaGapqMqb3052NOXbO |
19 |
|
This document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks detailed methodology and characterization of the test substance.
|
1985 |
AR226-0909
|
eLgE2nqY290n0Jz6qGKpweyp |
3 |
|
The document details an acute toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas) to evaluate its effects, noting that the test sample FX-3103 contains 0.96% PFOS among other components.
|
1985 |
AR226-0910
|
NEepGaZpYeeDzkvJdrmNxMy9R |
4 |
|
This document reports on a 1985 acute toxicity study of a PFOS-containing mixture (FX-3103) on the aquatic plant Selenastrum capricomutum, revealing a 96-hour IC50 value of 236 mg/L and significant growth inhibition at higher concentrations.
|
1985 |
AR226-0911
|
YrXJjKd0ZJJyK5zy3J9oGGaqy |
4 |
|
The document details an acute toxicity test of a PFOS-containing mixture (FX-3103) on Daphnia magna, indicating that the test was conducted under static conditions with a 48-hour exposure period, although the specific methodology and results are not fully provided.
|
1985 |
AR226-0912
|
99xd4r7pb2wY2q2ZKEVmOwBEp |
5 |
|
The document reports the results of a Microbios Microtox toxicity test on a mixture containing 0.96% PFOS, indicating that the EC50 values for Photobacterium phosphoreum were greater than 1000 mg/L, suggesting low toxicity for the tested mixture.
|
1985 |
AR226-0913
|
yk5nYBeEQRQJYk83jLjdkVKR2 |
4 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the 30-minute and 3-hour EC50 values were greater than 1000 mg/L, suggesting low toxicity at the tested concentrations.
|
1985 |
AR226-0914
|
44V4BnjoRRKDeeRzoMzJaODo1 |
5 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1985, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking detailed methodology and characterization of the test substance.
|
1985 |
AR226-0915
|
ZV9jkxOa4ZMEM6EO49YoDGmp |
3 |
|
The document reports on a toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic plant Selenastrum capricomutum, revealing a 96-hour IC50 value of 576 mg/L, indicating significant inhibition of algal growth at higher concentrations.
|
1985 |
AR226-0917
|
Ozn5jnEynGXm6aRnQvRbOodvX |
4 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.48% perfluorooctanesulfonate (PFOS) and other components, with the study completed in 1985 but lacking specific methodological details and GLP compliance.
|
1985 |
AR226-0916
|
xjz63j85JXpQaD3rnqxKxov7y |
4 |
|
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on the aquatic invertebrate Daphnia magna, indicating that the test sample FX-3104 consists of 0.48% PFOS among other components, although the toxicity data may not accurately reflect the fluorochemical component due to impurities.
|
1985 |
AR226-0918
|
0g9Q8yZn0KqyVE1LLgodJvb5k |
5 |
|
The document reports on a Microbics Microtox toxicity test conducted on a mixture containing 0.48% PFOS, indicating that the 5-minute and 15-minute EC50 values were greater than 1000 mg/L, suggesting low toxicity for the tested mixture.
|
1985 |
AR226-0919
|
YjKj06JNR3Gw5B5DX9MeoampO |
4 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the 30-minute and 3-hour EC50 values were greater than 1000 mg/L, suggesting low toxicity at the tested concentrations.
|
1985 |
AR226-0920
|
DMajVgwppXMzdZk878DG587eO |
4 |
|
This document reports on a biodegradation test of a mixture containing 2.31% perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high Chemical Oxygen Demand (COD) and varying Carbonaceous-Biochemical Oxygen Demand (BOD) results, but lacks comprehensive data quality and characterization of the test substance.
|
1985 |
AR226-0921
|
ayBjD8qgBBy7m1630VLB8YQN |
9 |
|
The document details an acute toxicity test conducted in 1985 on a mixture containing 2.31% perfluorooctanesulfonate (PFOS) using juvenile fathead minnows, which showed no mortality over a 96-hour exposure period.
|
1985 |
AR226-0922
|
YGNgOnegp82X52ZXJDXBeVyMK |
5 |
|
The document reports the results of a Microbios Microtox toxicity test on a mixture containing 2.31% PFOS, indicating that the 15-minute EC50 value for the mixture is greater than 1000 mg/L, suggesting low toxicity at the tested concentrations.
|
1985 |
AR226-0923
|
37NEe95V9oa7NBZmrJYqe797y |
4 |
|
The document is a correspondence from DuPont regarding the U.S. EPA Solid Waste Management Unit Survey, discussing the challenges of providing accurate records and engineering prints for solid waste management units at their facility, which has operated since 1948 and involves the reuse of plastics that are not considered hazardous under RCRA regulations.
|
1985 |
AR226-1331
|
babxg0OrRQzG0EOJ10NNbbdbo |
3 |
|
The document is an analytical report on FC-143 Lot 37, indicating that the substance, which is a perfluorinated compound, was characterized and found to be stable and representative of commercial material after pre and post-study analysis.
|
1985 |
AR226-0466
|
5Dvb1255LBb4E9nVo8QxNRmme |
2 |
|
The document reports on a biodegradation study of perfluorooctanoic acid (PFOA), also known as FX-1001, conducted by 3M Company, indicating that no reliable conclusions can be drawn due to insufficient characterization of the test substance and lack of raw data.
|
1985 |
AR226-0494
|
Evkgm5jR6o0Jw33ppJo6pZ7RL |
9 |
|
The document details an acute toxicity study of Perfluorooctanoic acid (PFOA) on the fish species Pimephales promelas, indicating that total mortality occurred at the highest concentration tested (870 mg/L) after a 96-hour exposure period.
|
1985 |
AR226-0509
|
Ex63RgXoQ5J5yn6a7G8jD6wjR |
5 |
|
The document reports on an acute inhalation toxicity study of T-3607 (perfluorooctyl sulfonyl fluoride) conducted by Bushy Run Research Center for 3M Company, finding no mortality or clinical signs of toxicity in rats exposed to a concentration of 3.74 mg/L.
|
1984 |
AR226-0206
|
Jv8w68EVx5jK5bpp55ezRLv0B |
12 |
|
The document reports that a primary skin irritation test conducted on T-3608 in female albino rabbits at Riker Laboratories, Inc. found it to be non-irritating, with no signs of erythema or edema observed.
|
1984 |
AR226-0237
|
zoeoyr9VgbOdoN1D7gL96pwN6 |
10 |
|
The document reports that cholestyramine significantly enhances the fecal elimination of carbon-14 from ammonium [14C]perfluorooctanoate (PFOA) and potassium [14C]perfluorooctanesulfonate (PFOS) in rats, reducing liver concentrations of these compounds compared to control rats.
|
1984 |
AR226-0008
|
rxV2XvGnyeLyMddzYer1NVrGE |
3 |
|
The document details a biodegradation test (OECD 301E) for a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample, FC-203 NFP, consists of 1.34% PFOS along with various other components, but notes that the data may not accurately reflect the biodegradability of the fluor
|
1984 |
AR226-0739
|
Qk7ByG6npMZV0BOgm2x3OvyKE |
15 |
|
The document details an acute toxicity test on fathead minnows (Pimephales promelas) using a mixture containing 1% perfluorooctanesulfonate (PFOS) and various other components, indicating that the data may not accurately reflect the toxicity of the fluorochemical due to incomplete characterization of impurities.
|
1984 |
AR226-0839
|
6RaVOBNvvYZ8kQmpjM4M1ambm |
7 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 1% PFOS, conducted using a sample from 3M, which found no inhibitory effect on the respiration rate of activated sludge at tested concentrations.
|
1984 |
AR226-0840
|
pGgRknwDM9OvwDvLOM8q2ge6 |
6 |
|
The document reports the results of an acute ocular irritation test conducted on the substance T-3493, indicating it is minimally irritating to the eyes of female albino rabbits, with only minimal conjunctivitis observed.
|
1984 |
AR226-0306
|
1eV29wODX7GoJ8d7284rER0m |
12 |
|
The document is a final report from SRI International detailing the results of in vitro microbiological mutagenicity assays conducted on 3M Company's Compound T-3609, which was found to be nonmutagenic and nonrecombinogenic.
|
1984 |
AR226-0310
|
NNkQ6QE10xQg36zdE1v6rO3z8 |
18 |
|
The document reports on a primary skin irritation test of the substance T-3494 conducted on female albino rabbits at Riker Laboratories, indicating that T-3494 is slightly irritating to the skin, with slight erythema observed but no edema.
|
1984 |
AR226-0313
|
rBg8wG2vjQxLvv21Op037p4x7 |
10 |
|
The document reports on an acute ocular irritation test of the substance T-3494 conducted on female albino rabbits at Riker Laboratories, indicating that T-3494 is minimally irritating to the eyes, with only temporary conjunctivitis observed.
|
1984 |
AR226-0314
|
oddQb611JQeJEyQdRMx7qeBD |
12 |
|
The document is a final report from SRI International detailing the results of in vitro mutagenicity assays conducted on 3M Company's Compound T-3610, which was found to be nonmutagenic and nonrecombinogenic in both the Ames Salmonella/microsome assay and the yeast Saccharomyces cerevisiae D3 assay.
|
1984 |
AR226-0316
|
QXdJ8p5ymjeKMaxQB4nQ3x9X6 |
18 |
|
The document reports on a biodegradation study of N-Ethylperfluorooctanesulfonamide (FX-12) conducted by 3M Company, indicating that the substance is not capable of readily biodegrading in aerobic environments, with a 20-day BOD of <940 mg/kg and a COD of 22,000 mg/kg.
|
1984 |
AR226-0336
|
Byz84REnkb7dKKBmMOqzbB5Ok |
4 |
|
The document reports on an acute toxicity study conducted by 3M Company in 1984, which found that N-Ethylperfluorooctanesulfonamide (EtFOSA) has a 96-hour LC50 of 34 mg/L for the fish species Pimephales promelas, although the study's reliability is questioned due to issues with sample purity and concentration measurement.
|
1984 |
AR226-0339
|
dnpgMk9Lb2d5vD1dEo1mwyan0 |
5 |
|
The document reports on a toxicity study conducted by 3M Company in 1984, which found that N-Ethylperfluorooctanesulfonamide (EtFOSA) has an EC50 of 3.2 mg/L for immobilization of daphnids, although the study's reliability is questioned due to unmeasured actual concentrations and inadequate characterization of sample purity.
|
1984 |
AR226-0341
|
NekbJ8qrO1aqV9B1wB6a3rvnD |
5 |
|
The document reports on a solubility screening study conducted by 3M Company in 1984 for perfluorooctanesulfonyl fluoride (FX-8), indicating that it is slightly soluble in water with measured total organic carbon (TOC) values below 2 mg/L across various nominal concentrations, but the study lacks sufficient quality due to uncharacterized purity and indirect measurement methods
|
1984 |
AR226-0374
|
ZJDVnMM0REKBErmGm46XV4MMV |
6 |
|
The document reports on an activated sludge respiration inhibition test conducted by 3M Company, which found that perfluorooctanesulfonyl fluoride (POSF) exhibited no inhibitory effect on respiration at a concentration of 1000 mg/L over a 6.75-minute exposure.
|
1984 |
AR226-0375
|
qep8m6vM7OwjLXqNYw70E9mK |
6 |
|
The document reports on an acute toxicity test of perfluorooctanesulfonyl fluoride (POSF) on the fish species Pimphales promelas, indicating that the 24, 48, and 96-hour LC50 values were all greater than 1000 mg/L, suggesting low toxicity at the tested concentrations.
|
1984 |
AR226-0376
|
MGQOmGj6Z4wMxd1J2YkKQx5M7 |
6 |
|
The document reports on a biodegradation study conducted by 3M Company on the test substance 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate, indicating that it is not capable of readily biodegrading in aerobic environments, with significant biochemical oxygen demand (BOD) results over 20 days.
|
1984 |
AR226-0411
|
MGkgKBQ7Rd6L70y2o08Nr2xBy |
8 |
|
The document reports on an activated sludge respiration inhibition test conducted by 3M Company, which found that the test substance 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate (B1228) exhibited no inhibitory effect on respiration at a concentration of 1000 mg/L after 6.65 minutes of exposure, indicating an EC50 greater than
|
1984 |
AR226-0414
|
dDxjJpVZjjZXbxXxXX7vpeM55 |
4 |
|
The document reports on an acute toxicity study of the perfluorinated compound EtFOSEA (2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate) on fathead minnows, concluding that the 96-hour LC50 is greater than 1000 mg/L, indicating low toxicity at the tested concentrations.
|
1984 |
AR226-0413
|
ybgbop3yozYmG7ZBN7K8wgLBD |
4 |
|
The document reports on an oral teratology study of T-3141CoC, conducted by 3M Commercial Chemical Division, which found that the compound did not cause embryotoxicity or teratogenic effects in pregnant rabbits at doses up to 50 mg/kg/day, although the high dose group experienced significant weight loss.
|
1984 |
AR226-0465
|
gEYr0Bg543yKqd4dd469K1RKJ |
29 |
|
The document reports on the inorganic fluoride test results for personnel from Building 15, indicating no increased levels of inorganic fluoride exposure among the group despite previous concerns related to organic fluorine determinations.
|
1984 |
AR226-0482
|
0LLNVY6BKv0xGnz5yNGzEJwn |
3 |
|
The document discusses concerns regarding increasing blood fluorine levels among employees in Building 15, linked to the handling of organic fluorine compounds, indicating a need for improved protective measures if the trend continues.
|
1984 |
AR226-0483
|
e2YVjvoaM6nMaeBxJNgBR6vg |
4 |
|
The document reports on a respiration inhibition test conducted on 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro, in compliance with OECD Guideline No. 209, sponsored by the Telomer Research Project involving companies such as DuPont
|
1984 |
AR226-1220
|
vVZZ9j8ZX3GOE1ZXJr7EJ26yE |
30 |
|
The document presents data on C-8 (PFOA) levels in drinking water from various locations near the No. 5 outfall, indicating detectable levels in the Lbeck Water District and Little Hocking, while other locations showed non-detectable levels from 1984 to 1988.
|
1984 |
AR226-1410
|
6b06LXONjpNEnNn4EObZg0OZE |
1 |
|
The document reports on an acute toxicity test of 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro conducted on earthworms (Eisenia fetida) according to OECD Guideline 207, sponsored by the Telomer Research Project
|
1984 |
AR226-1429
|
zoaa6bYdJVq0rEY32mpdG3OKa |
33 |
|
The document outlines a request to schedule annual C-8 (PFOA) blood tests for EPD Operators in a specific month starting in 1985 to improve efficiency in sample analysis and timely reporting of results.
|
1984 |
AR226-1635
|
wJ6o6o0jqEqMG09vG1b4qL5J |
2 |
|
The document provides an update on the C-8 (perfluorooctanoic acid, PFOA) blood sampling program, indicating that Fine Powder/Dispersion Operators experienced an average 24% drop and FEP Operators a 12% drop in blood C-8 levels over the past 2 to 3 years, based on recent blood sample results.
|
1984 |
AR226-1634
|
2BMYRVLd6kxQVez9rRm8Y1Mb |
22 |
|
The document reports on a primary skin irritation test of the substance T-3421, conducted on female albino rabbits at Riker Laboratories, indicating that T-3421 is moderately irritating to the skin.
|
1983 |
AR226-0212
|
b5jp8yV7xyyMkyrbXwJbja3no |
10 |
|
The document reports the results of an acute ocular irritation test for the substance T-3421 conducted on female albino rabbits, indicating that T-3421 is moderately irritating to the unwashed eye and mildly irritating under limited contact conditions, with various levels of corneal opacity and conjunctivitis observed during the evaluations.
|
1983 |
AR226-0211
|
2J7JXka84Eee8JvnNmwQyN6dg |
15 |
|
This is a letter from Dr. E. Marshall Johnson at Jefferson Medical College to Mr. William C. McCormick at 3M, providing a review of a developmental toxicity study on T3351, highlighting its safety for embryonic development despite maternal toxicity observed at higher doses.
|
1983 |
AR226-0015
|
dYnVr7DD64O3yq0NoNdBve8Q |
2 |
|
This is a final report from Hazleton Laboratories America, Inc. for a Rat Teratology Study (Project No. 154-160) submitted to 3M Company on December 19, 1983, detailing the study's methodology, results, and quality assurance inspections.
|
1983 |
AR226-0014
|
baBXpm8ZDvj935e3vD0nOv6pD |
83 |
|
The document details a biodegradation test (OECD 301E) conducted on a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the test sample is FC-203, which consists of 1.34% PFOS among other substances, but notes that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization
|
1983 |
AR226-0712
|
MJqjxMrOaLwJ2OD7z5g6pBkqV |
14 |
|
The document details a biodegradation test (OECD 301 E) conducted on a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample FC-203 consists of 1.34% PFOS along with various other components, and notes that the data may not accurately reflect the degradation potential of the fluorochemical due to incomplete
|
1983 |
AR226-0713
|
dQb922mGDJKdKvk50ZzeKe2JG |
23 |
|
The document details an activated sludge respiration inhibition test conducted on a mixture containing 1.0% perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the data may not accurately reflect the inhibition caused by the fluorochemical component due to impurities.
|
1983 |
AR226-0831
|
jVLNnvbqz31m4rbgQRoezvrO |
4 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0833
|
gDbkqjb1G0XJo546aEqDNrRwe |
4 |
|
The document describes an activated sludge respiration inhibition test conducted on a mixture containing 1.0% PFOS, produced by 3M, to assess its impact on oxygen consumption, although the results may not accurately reflect the inhibition due to impurities in the test sample.
|
1983 |
AR226-0832
|
rpjdVyDRJ3vqJLy6O5mkOJVXq |
4 |
|
The document details an acute toxicity test on a mixture containing 1.0% PFOS conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0834
|
QMmLo96p2M1zqmpJJoJmerzE4 |
4 |
|
The document reports on an acute toxicity test of a mixture containing 1.0% PFOS conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0835
|
QgMqKoVmKdpjXgZZGVeXR0qqR |
4 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0836
|
85a6R5jEOYpDQQn9r5yQQdgkd |
4 |
|
The document provides an overview of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), including its identity, physical characteristics, and mentions that robust summaries of individual studies are being submitted by 3M Company, while some older studies are not summarized due to the existence of newer research.
|
1983 |
AR226-0365
|
n219X55VLYZnymaDv1gz1Qxz |
36 |
|
The document reports on a study conducted by Riker Laboratories Inc. on the absorption, biotransformation, tissue distribution, and elimination of Carbon-14 labeled N-Ethyl FOSE (2-N-ethyl perfluorooctanesulfonamido ethanol) in animals after administration in feed.
|
1983 |
AR226-0965
|
wrwXG3p7rVgrnM5m6pV6LN7do |
57 |
|
The document reports on a primary skin irritation test conducted on T-3371, a substance tested at Riker Laboratories, which resulted in irreversible tissue damage and severe irritation in female albino rabbits after various contact periods.
|
1983 |
AR226-0424
|
kvO5xzXoE8KNgEDn3VwkBORV |
12 |
|
This document reports that hormonal changes during pregnancy do not affect the rate of elimination of carbon-14 from ammonium C-perfluorooctanoate in pregnant rats, with nearly all carbon-14 excreted via urine within 24 hours, indicating no accumulation in tissues during repeated dosing in teratology studies.
|
1983 |
AR226-0458
|
ZnM9vZrRYOYE8XdGBRe9Nrw4d |
6 |
|
The document is a recommendation from Bruce W. Karrh, M.D. of E.I. du Pont de Nemours & Company to proceed with FC-143 blood tests on employees at the F&F plant, specifically those in Teflon-related jobs, following a previous letter dated April 8, 1982.
|
1983 |
AR226-1626
|
xzy7ZejeEJgz6Br3pxDNGqmk6 |
1 |
|
The document reports a statistically significant drop in blood C-8 (PFOA) levels among TEFLON Fine Powder/Dispersion and FEP Operators, indicating a 13% decrease over two years, with average levels of 5.5 ppm and 1.2 ppm respectively.
|
1983 |
AR226-1627
|
peymZdrV1kakR53RQoEGzO9od |
5 |
|
The document reports the analysis of blood samples from Tralee Park employees for perfluorooctanoate (PFOA), revealing concentrations of 0.17 and 0.15 µg/g blood, using gas chromatography.
|
1983 |
AR226-1628
|
wKbBYL05RDwg9MRMzdjrj5Qo |
2 |
|
This document provides detailed blood C-8 (PFOA) level data for employees at E.I. du Pont de Nemours Company's Washington Works who have not worked in the Fluoropolymers Division, indicating that blood C-8 levels are low and reach equilibrium in less than a year.
|
1983 |
AR226-1631
|
71EppmgRdb5ma68bVJOoQOgkV |
2 |
|
The document is a final report from SRI International assessing the mutagenic and recombinogenic activity of 3M Company's Compound T-3290CoC using in vitro assays, concluding that the compound was neither mutagenic nor recombinogenic.
|
1982 |
AR226-0222
|
req3nxDzoBm7yoY8L1N7NJqjV |
16 |
|
The document discusses a review of anatomical specimens related to a study on the effects of a test substance, indicating that previously reported abnormalities in fetal rat eyes were misidentified and that the evaluation process lacked proper controls, which undermines the validity of the findings.
|
1982 |
AR226-0017
|
K6np9KvxXKmxJYMV6m9oKG4R0 |
2 |
|
This document presents a biodegradation study of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1982, reporting high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking detailed methodology and data reliability.
|
1982 |
AR226-0685
|
q3Yxa5m58dD56Jq6RDL3dNVpR |
3 |
|
The document details an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using juvenile Pimephales promelas, with specific test conditions and methods outlined, although it notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1982 |
AR226-0686
|
5kL9neJO6Bd38ZjgBjQBwo5v4 |
12 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 4% PFOS, conducted by 3M, which found no inhibition of activated sludge respiration at a concentration of 1000 mg/L.
|
1982 |
AR226-0687
|
OzLQBM4ZzwodKgy5MgRd8m1we |
4 |
|
The document summarizes a study conducted by the German Army on the environmental properties of foam extinguishing agents, specifically a mixture containing 1.34% PFOS, and reports various toxicity levels including EC50 values for Photobacterium phosphoreum, Scenedesmus subspicatus, Daphnia magna, and Brachydanio rerio.
|
1982 |
AR226-0733
|
La1wpN5ZBx6QV87JZEOBkwY3 |
26 |
|
The document summarizes a study conducted by the German Army on the environmental properties of foam extinguishing agents, specifically noting that the test sample FC-206 contains 0.67% PFOS and provides various toxicity results including EC50 values for Photobacterium phosphoreum, freshwater algae, and Daphnia magna.
|
1982 |
AR226-0792
|
Z8JadgGRMJrg8wDNxqenxm4Ep |
26 |
|
The document reports on an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% PFOS, indicating no mortality during the 96-hour exposure period.
|
1982 |
AR226-0838
|
ppdxjvEGZgbEagwZLRyvLb2XB |
12 |
|
The document summarizes biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) from 3M, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn due to insufficient methodological details.
|
1982 |
AR226-0868
|
65b23RQkqD1jyB9V2Nqr2K8Z3 |
9 |
|
The document is an analytical report confirming that FM-3924, a perfluorinated compound, meets quality control specifications and is stable, based on various chemical analyses conducted for Riker's teratology study.
|
1982 |
AR226-0279
|
0gw393yZY0ZoxJR2bmR22g9bV |
2 |
|
The document is an internal analytical report evaluating the chemical FM-3924, which was analyzed for a Riker teratology study, confirming its structure and providing detailed gas chromatography and elemental analysis results.
|
1982 |
AR226-0286
|
4JvZJN8Q3j9V2DQmmrobwJ1bj |
2 |
|
The document reports on a biodegradation test of Perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) conducted by 3M Company, indicating that while some biodegradation occurred in aerobic conditions, the specific contribution of the test substance to the observed chemical and biochemical oxygen demand values remains unclear due to the mixture's composition and lack of detailed methodology.
|
1982 |
AR226-0392
|
JJL1bGXGL5MZ4JJNwv6JqEV1e |
7 |
|
The document is a letter from Dr. E. Marshall Jo to Dr. Franklin D. Griffith stating that FC143, a substance tested for developmental toxicity in pregnant rats and rabbits, poses no hazard to the conceptus, and therefore no further testing is necessary.
|
1982 |
AR226-0467
|
mb94OQ9L15qjRm982XZJgv7dk |
1 |
|
The document is an internal correspondence summarizing health evaluations conducted in 1981 for 264 employees at Chemolite, with a focus on comparing testing data with blood fluorine levels as part of the fluorochemical program.
|
1982 |
AR226-0480
|
rB397Rq1Badxg2o6jZr4oJZZr |
1 |
|
The document details a chronic toxicity study of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) on freshwater invertebrates (Daphnia magna), conducted by 3M, indicating that the test substance was a mixture with a purity of 96.5 - 100% and outlining the methodology and conditions of the study.
|
1982 |
AR226-0508
|
dQ78GXjN7j34041EjbBJQxMrq |
25 |
|
The document is a letter from Dr. Franklin D. Griffith expressing gratitude for the cooperation received during a visit to 3M, where he reviewed raw data and specimens related to a study on fetal rat eyes, ultimately concluding that many previously reported abnormalities were actually normal findings, indicating issues with the original study's methodology.
|
1982 |
AR226-0530
|
wrxMyZjn5ZO9m2gKXg6ZGj64Q |
2 |
|
The document reports on blood C-8 (PFOA) levels among employees at E. I. du Pont de Nemours & Company, indicating higher accumulation rates in Fine Powder Zone 4 Operators compared to FEP Zone 4 Operators, with a general downward trend observed in long-term employees, although further data is needed for statistical significance.
|
1982 |
AR226-1612
|
n9oL6kex21VJ4jXx54Ewjjrpm |
5 |
|
The document discusses recommendations for periodic blood tests for employees potentially exposed to FC-143, indicating that "Teflon" operators have low blood levels and exposure, and suggests these tests be included in their routine physical examinations.
|
1982 |
AR226-1613
|
pBn9NwgXJqLY8wLo0GOpnxaXa |
1 |
|
This document reports on the detection of organic fluoride levels in the blood of Experimental Station employees, linked to by-products from HFPO synthesis, and outlines a program to investigate health impacts and improve monitoring related to this exposure.
|
1982 |
AR226-1615
|
xG3VrjEpN7Mm8m6j71LNxq7b |
1 |
|
The document outlines a plan by DuPont and 3M to reduce blood sampling for C-8 (perfluorooctanoic acid, PFOA) among employees, focusing on those with direct exposure, while continuing to monitor certain individuals to assess the elimination rate of C-8 from the blood.
|
1982 |
AR226-1616
|
BRRD3jRy0ZRVBvQbKmEOVE31E |
1 |
|
The document outlines a procedure for analyzing blood serum for FC-143, a perfluorinated compound, detailing the extraction and conversion methods used to prepare samples for gas chromatography analysis.
|
1982 |
AR226-1614
|
nkNNRkN1a8gZjr7GG0z66mBwR |
3 |
|
The document reports on trends in blood C-8 (PFOA) levels among TEFLON employees, indicating a significant average decrease of 23% for FEP Operators and 18% for Fine Powder and Granular Operators from October 1981 to June 1982, while new employees are accumulating C-8 at a lower rate than in previous years.
|
1982 |
AR226-1617
|
by75VenR65YdnBbL1Odda3kL0 |
9 |