1980s

Documents dated 1980–1989.

Page 2 of 6 — 597 documents
Title / Summary Year AR226 Docket Hash ID Pages
Empty document. 1987 AR226-3630 pB2jap19LB1kNJKLe1zy324wd 1
The document is a review letter discussing a two-year toxicity and carcinogenicity study of PFOA (fluorochemical FC-143) in rats, authored by Greg Sykes from Haskell Laboratory for Toxicology and Industrial Medicine and addressed to Charles Reinhardt. 1987 AR226-3630 O1exVM1VgqRQRmDm05RvkvBDL 1
Empty document. 1987 AR226-3630 3N3RxGKRogjQ8rg7yD4m6B893 1
The document is an attachment to a letter from 3M detailing various studies and reviews related to the toxicity and carcinogenicity of perfluorooctanoic acid (PFOA), including findings from rat and monkey studies conducted by different laboratories. 1987 AR226-1916 N2BYmyEx2BwdZQ54zOwE28nEQ 1
The document reviews a two-year toxicity and carcinogenicity study of fluorochemical FC-143 conducted by 3M Company, highlighting findings of hepatic toxicity and non-neoplastic lesions in rats, with a specific focus on liver damage and enzyme elevation in male rats. 1987 AR226-1917 VjK1ddyYDY35873xv70BGqpKK 6
The document reports on C-8 (perfluorooctanoic acid, PFOA) ground-level concentrations at Washington Works, indicating that both pre- and post-May 1981 shutdown concentrations are well below the provisional acceptable exposure level (AEL) of 10 µg/m³, with the highest annual mean concentration being only about 5% of the AEL. 1987 AR226-1987 7Rqd7p2mY2GXg9EOV11pkQDdV 2
The document outlines a review of the C-8 control program related to perfluorinated compounds (specifically C-8, which refers to PFOA) and emphasizes the need for environmental monitoring and employee blood testing protocols to manage exposure levels. 1987 AR226-2142 oD7LyonQj6Do8Ke5bBg03Jg2w 3
The memorandum discusses the detection of C8 (likely PFOA) in water samples from various locations, including drinking fountains and stores in West Virginia and Ohio, with specific concentration results noted. 1987 AR226-2390 8Vej0XNR08n83qa5JnLq1mQzk 1
This analytical report details the detection of perfluorooctanoate (C8) in five water samples, using electron capture gas chromatography, with a detection limit established at 0.4 ppb, and results indicating that only two samples contained detectable levels of C8. 1987 AR226-2391 2Rpg7EmQN1znOywd0OGXbRNG6 2
This memorandum discusses the analytical results of five water samples for perfluorooctanoate (C8) collected from various locations, indicating a detected concentration of 1.9 ppb, which is higher than previous results but likely not significantly different due to proximity to the detection limit. 1987 AR226-2392 zdyoVZK0JYbNZmRwpejZQErQg 3
The document reports on a study conducted by E.I. du Pont de Nemours and Company, which determined the approximate lethal concentration of a substance (Du Pont HLR 624-87) in male Crl:CD*BR rats exposed to aerosol/vapor atmospheres, finding that an atmospheric concentration of 230 mg/m³ did not result in common clinical signs of toxicity in surviving rats after a 1987 AR226-2934 dam96gwzzRjgQ2GMyvKzMYzJQ 10
The document is a report from Du Pont's Haskell Laboratory indicating that the test materials, which were evaluated using repeated-insult patch tests, were found to be neither primary skin irritants nor sensitizing agents. 1987 AR226-2932 nmBeqxy3X3dwrzRJMBGKqKMb8 34
This is a DuPont report (Project ID: DuPont-9104) detailing an acute eye irritation/corrosion study conducted on rabbits, completed on January 3, 2002, in accordance with OECD guidelines. 1987 AR226-3213 Ego8ezKmo1vkm306nyLVQYGR 16
The document is a request from DuPont to establish acceptable levels for ammonium perfluorooctanoate (C-8) in blood and community drinking water. 1987 AR226-1636 emd9Bw5dVV5zwdYLqRng6nKdq 1
The report by Beak Consultants Limited for Panarctic Oils Ltd. evaluates the potential environmental impacts of using the perfluorinated surfactant AFA-6 in Arctic exploration, noting its slow biodegradation, toxicity levels comparable to marine organisms, and low bioconcentration potential, while suggesting that dilution during melting will likely mitigate environmental risks. 1986 AR226-1030 LgzZ5mjwg4Lw6ZBe7QQ43z6Vw 31
The document is a report by Beak Consultants Limited for Panarctic Oils Ltd. regarding the potential environmental impacts of the perfluorinated surfactant AFA-6, which is proposed for use in Arctic exploration, indicating concerns about its toxicity and bioconcentration potential in marine organisms. 1986 AR226-1030 v1kgrOYZ21qKLmXdZMGJRe8Lq 31
The report by Beak Consultants Limited for Panarctic Oils Ltd. evaluates the potential environmental impacts of using the perfluorinated surfactant AFA-6 in Arctic exploration, finding that its application at 10 mg/L poses toxicity risks to marine organisms but has limited bioconcentration potential and will likely be diluted during ice melting. 1986 AR226-1030 nmJrjBZj08krMRLK1GLkR2G5a 31
The report by Beak Consultants Limited for Panarctic Oils Ltd. evaluates the potential environmental impacts of using the perfluorinated surfactant AFA-6 in Arctic exploration, indicating that while it biodegrades slowly and has low bioconcentration potential, its application at 10 mg/L poses toxicity risks to marine organisms. 1986 AR226-1030 M4aB87gkygnK8wzekJ2ZQj2Xx 31
The document reports that a primary skin irritation test conducted on T-3874 at Riker Laboratories, Inc. found it to be non-irritating to the skin of female albino rabbits, with no signs of erythema or edema observed. 1986 AR226-0205 N23vQryYQ1Eym338Kr07XLEKy 10
The report by Beak Consultants Limited for Panarctic Oils Ltd. evaluates the potential environmental impacts of the perfluorinated surfactant AFA-6, indicating that its application at a concentration of 10 mg/L poses toxicity concerns for marine organisms, but estimates low bioconcentration potential and limited environmental impact due to dilution during melting. 1986 AR226-1030 vVqk5rDQ41meLvJd3LNjrGgn8 31
The document reports that a primary skin irritation test conducted on T-3874 at Riker Laboratories, Inc. found it to be non-irritating to the skin of female albino rabbits, with no signs of erythema or edema observed. 1986 AR226-0205 MJwgQjXwL5aewGnJKb39L5y3y 10
The document discusses the spreading kinetics of aqueous solutions of a mixture of hydrocarbon and fluorocarbon surfactants, specifically focusing on a commercial AFFF (aqueous film-forming foam) agent, and establishes an empirical relationship between the rate of spreading and various experimental parameters. 1986 AR226-1315 xjgK9yaDLBKgqGjodQz4Gdb7g 10
The Haskell Laboratory Report No. 799-85 evaluates the acute eye irritation potential of a substance produced by E.I. du Pont de Nemours and Company, finding that it caused slight corneal opacity in unwashed eyes but returned to normal within three days. 1986 AR226-2796 k9BmabpRBrVMMJJ2b346X5v4q 12
The document is a Haskell Laboratory report from E. I. du Pont de Nemours and Company detailing an inhalation toxicity study on perfluorinated compounds, indicating that the tested substance was slightly toxic on an acute inhalation basis. 1986 AR226-2931 82Bm0zZz5jEdrgJYNeRENydgo 7
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3752, which was found to be reproducibly non-mutagenic and non-recombinogenic according to standard testing procedures. 1985 AR226-0247 O5pQ7b7qbayZLJM0kE4D9R6w 20
The document is a final report from Hazleton Laboratories America, Inc. detailing an acute oral toxicity study of the test material T-3727, which is associated with the Minnesota Mining and Manufacturing Company, conducted on Sprague-Dawley rats according to OECD guidelines. 1985 AR226-0245 YDQ27XZ4K83xB1xNGe12xQR9V 102
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's compound T-3727, which concluded that T-3727 was reproducibly non-mutagenic when tested according to standard procedures. 1985 AR226-0248 8V4MO34EyKMOpDdODR9GRRxzK 16
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3752, which was found to be reproducibly non-mutagenic and non-recombinogenic in tests conducted according to FDA Good Laboratory Practice Standards. 1985 AR226-0247 RjYv18jQdzbQ2xJ9gd3x9Bd8B 20
The document is a final report from Hazleton Laboratories America, Inc. detailing an acute oral toxicity study of the test material T-3727, which is associated with Minnesota Mining and Manufacturing Company, using Sprague-Dawley rats to assess its safety according to OECD guidelines. 1985 AR226-0245 R7KoLd46Yz7jamN7eMvVv14E 102
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3727, which was found to be reproducibly non-mutagenic when tested using the standard Ames Salmonella/microsome assay. 1985 AR226-0248 RaeQKa0d1Vz7dXDqzXDparJKV 16
The document is a final report from SRI International detailing the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3651, which was found to be nonmutagenic and nonrecombinogenic in the tested assays. 1985 AR226-0684 0qXng7qXaGapqMqb3052NOXbO 19
This document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks detailed methodology and characterization of the test substance. 1985 AR226-0909 eLgE2nqY290n0Jz6qGKpweyp 3
The document details an acute toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas) to evaluate its effects, noting that the test sample FX-3103 contains 0.96% PFOS among other components. 1985 AR226-0910 NEepGaZpYeeDzkvJdrmNxMy9R 4
This document reports on a 1985 acute toxicity study of a PFOS-containing mixture (FX-3103) on the aquatic plant Selenastrum capricomutum, revealing a 96-hour IC50 value of 236 mg/L and significant growth inhibition at higher concentrations. 1985 AR226-0911 YrXJjKd0ZJJyK5zy3J9oGGaqy 4
The document details an acute toxicity test of a PFOS-containing mixture (FX-3103) on Daphnia magna, indicating that the test was conducted under static conditions with a 48-hour exposure period, although the specific methodology and results are not fully provided. 1985 AR226-0912 99xd4r7pb2wY2q2ZKEVmOwBEp 5
The document reports the results of a Microbios Microtox toxicity test on a mixture containing 0.96% PFOS, indicating that the EC50 values for Photobacterium phosphoreum were greater than 1000 mg/L, suggesting low toxicity for the tested mixture. 1985 AR226-0913 yk5nYBeEQRQJYk83jLjdkVKR2 4
The document reports on an activated sludge respiration inhibition test for a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the 30-minute and 3-hour EC50 values were greater than 1000 mg/L, suggesting low toxicity at the tested concentrations. 1985 AR226-0914 44V4BnjoRRKDeeRzoMzJaODo1 5
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1985, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking detailed methodology and characterization of the test substance. 1985 AR226-0915 ZV9jkxOa4ZMEM6EO49YoDGmp 3
The document reports on a toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic plant Selenastrum capricomutum, revealing a 96-hour IC50 value of 576 mg/L, indicating significant inhibition of algal growth at higher concentrations. 1985 AR226-0917 Ozn5jnEynGXm6aRnQvRbOodvX 4
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.48% perfluorooctanesulfonate (PFOS) and other components, with the study completed in 1985 but lacking specific methodological details and GLP compliance. 1985 AR226-0916 xjz63j85JXpQaD3rnqxKxov7y 4
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on the aquatic invertebrate Daphnia magna, indicating that the test sample FX-3104 consists of 0.48% PFOS among other components, although the toxicity data may not accurately reflect the fluorochemical component due to impurities. 1985 AR226-0918 0g9Q8yZn0KqyVE1LLgodJvb5k 5
The document reports on a Microbics Microtox toxicity test conducted on a mixture containing 0.48% PFOS, indicating that the 5-minute and 15-minute EC50 values were greater than 1000 mg/L, suggesting low toxicity for the tested mixture. 1985 AR226-0919 YjKj06JNR3Gw5B5DX9MeoampO 4
The document reports on an activated sludge respiration inhibition test for a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the 30-minute and 3-hour EC50 values were greater than 1000 mg/L, suggesting low toxicity at the tested concentrations. 1985 AR226-0920 DMajVgwppXMzdZk878DG587eO 4
This document reports on a biodegradation test of a mixture containing 2.31% perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high Chemical Oxygen Demand (COD) and varying Carbonaceous-Biochemical Oxygen Demand (BOD) results, but lacks comprehensive data quality and characterization of the test substance. 1985 AR226-0921 ayBjD8qgBBy7m1630VLB8YQN 9
The document details an acute toxicity test conducted in 1985 on a mixture containing 2.31% perfluorooctanesulfonate (PFOS) using juvenile fathead minnows, which showed no mortality over a 96-hour exposure period. 1985 AR226-0922 YGNgOnegp82X52ZXJDXBeVyMK 5
The document reports the results of a Microbios Microtox toxicity test on a mixture containing 2.31% PFOS, indicating that the 15-minute EC50 value for the mixture is greater than 1000 mg/L, suggesting low toxicity at the tested concentrations. 1985 AR226-0923 37NEe95V9oa7NBZmrJYqe797y 4
The document is a correspondence from DuPont regarding the U.S. EPA Solid Waste Management Unit Survey, discussing the challenges of providing accurate records and engineering prints for solid waste management units at their facility, which has operated since 1948 and involves the reuse of plastics that are not considered hazardous under RCRA regulations. 1985 AR226-1331 babxg0OrRQzG0EOJ10NNbbdbo 3
The document is an analytical report on FC-143 Lot 37, indicating that the substance, which is a perfluorinated compound, was characterized and found to be stable and representative of commercial material after pre and post-study analysis. 1985 AR226-0466 5Dvb1255LBb4E9nVo8QxNRmme 2
The document reports on a biodegradation study of perfluorooctanoic acid (PFOA), also known as FX-1001, conducted by 3M Company, indicating that no reliable conclusions can be drawn due to insufficient characterization of the test substance and lack of raw data. 1985 AR226-0494 Evkgm5jR6o0Jw33ppJo6pZ7RL 9
The document details an acute toxicity study of Perfluorooctanoic acid (PFOA) on the fish species Pimephales promelas, indicating that total mortality occurred at the highest concentration tested (870 mg/L) after a 96-hour exposure period. 1985 AR226-0509 Ex63RgXoQ5J5yn6a7G8jD6wjR 5
The document is an analytical report on FC-143 Lot 37, indicating that the substance, which is a perfluorinated compound, has been characterized and found to be stable and representative of commercial material, based on various pre and post-study analyses conducted by L. D. Winter for Riker. 1985 AR226-0466 xjMw8Ed4EybDOMmQnm6eR8vpb 2
The document is an archived final report from 3M Company detailing a biodegradation study of perfluorooctanoic acid (PFOA, FX-1001) conducted in 1985, which concluded that no reliable conclusions could be drawn due to insufficient characterization of the test substance and lack of analytical confirmation. 1985 AR226-0494 LgkbdJV4d1ywrD0K2aZY0qdjq 9
This document details an acute toxicity study of Perfluorooctanoic acid (PFOA) on the fish species Pimephales promelas, conducted in 1985, which involved a 96-hour exposure to varying concentrations of PFOA, revealing total mortality at the highest concentration tested. 1985 AR226-0509 a58oBVJ637edqmQew4vEZnGa 5
Empty document. 1985 AR226-1985 2qaZO67eVgoaJbKEaJzYkzazg 1
The document discusses the analysis of river water samples for C-8 (PFOA) by the Washington Works Teflon Polymers Business Team, noting interferences from organic contaminants that complicate the analysis and highlighting the need for method development to accurately determine C-8 levels in river water and mud. 1985 AR226-2389 8RE73ZnON3k53xdjDw1RoVg3a 1
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal concentration (ALC) of Ammonium Perfluorononanoate (C-9) by inhalation in rats, finding an ALC of 590 mg/m3 and noting significant liver weight changes and lesions in exposed subjects. 1985 AR226-2790 jgOD5dwxB5NGoZRG4vERx7mjk 15
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal concentration (ALC) of a perfluorinated compound in rats, finding that the ALC was 160 mg/L and indicating that the material has very low toxicity by inhalation. 1985 AR226-2791 5knMYqMGJZMDYwLYeBYG3nr1N 7
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal concentration (ALC) of perfluorooctanoic acid (PFOA) by inhalation in male rats, finding an ALC of 590 mg/m³ and noting significant liver weight changes and pathological liver lesions in exposed animals. 1985 AR226-2794 EzNp5qj1b06M9Xp3KzoG35q0 16
The document is a Haskell Laboratory report detailing a subchronic inhalation toxicity study of PFOA in rats, which found elevated serum aspartate aminotransferase activity and decreased cholesterol concentrations in rats exposed to 30 mg/L of the compound. 1985 AR226-2792 rBj8wmqaZGJ5eZKqBMyqNx8BG 74
The document is a Haskell Laboratory report detailing an acute toxicity study conducted by E. I. du Pont de Nemours and Co. on the inhalation of a substance, which is not specified in the text, but indicates that the tested concentration of up to 2100 mg/m³ resulted in no deaths among male rats, suggesting very low acute toxicity. 1985 AR226-2926 M4QmXQOV5Gj8xkg5Zm15BOQ0k 6
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal concentration by inhalation (ALC) of a perfluorinated compound, indicating that the ALC was greater than 1200 mg/m³, classifying the material as no worse than slightly toxic by inhalation. 1985 AR226-2928 r6RooNo9abQM71rL0drM2BxE 7
The document reports on a study conducted by E. I. du Pont de Nemours & Company to assess the static acute toxicity of a substance identified as Haskell No. 15,866 to the freshwater macroinvertebrate Daphnia magna, finding a 48-hour EC50 value of 210 mg/L. 1985 AR226-2929 M867gqDdJMpEzexqZY74kvXa 7
The document is a Haskell Laboratory report from E. I. du Pont de Nemours and Company detailing a study on the static acute toxicity of a substance (unspecified in the text) to the fathead minnow (Pimephales promelas), which found a 96-hour LC50 of 2341 mg/L. 1985 AR226-2930 ZB4kXwoZ9gjgExE4wk00pLg8Z 7
The document reports on a subchronic inhalation toxicity study conducted by E. I. du Pont de Nemours and Co. on male rats exposed to varying concentrations of a perfluorinated compound (PFAS) for two weeks, revealing significant adverse effects on body weight and hematologic and clinical chemical parameters at the highest concentration of 480 mg/m³, although these effects were not present after 1985 AR226-2927 kDOyEejjb9gExpR8Xp0Gq78VE 154
The document is a final report on the in vitro microbiological mutagenicity assays of 3M Company's Compound T-3651, which was found to be reproducibly nonmutagenic and nonrecombinogenic in tests conducted by SRI International. 1985 AR226-0684 V34NX4j7x4z1w2EmOzrQddz4w 19
This document presents a biodegradation test report for a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1985, indicating high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking detailed methodology and characterization of the test substance. 1985 AR226-0909 mqXNapZ398Qq3vjdGE1o8opqk 3
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.96% PFOS, revealing that the test sample FX-3103 was not fully characterized and may not accurately reflect the toxicity of its fluorochemical component. 1985 AR226-0910 pjRZaa71vd41Y1d5kYyGpEkB 4
This document reports on a toxicity study of a PFOS-containing mixture (FX-3103) on the aquatic plant Selenastrum capricomutum, revealing a 96-hour IC50 value of 236 mg/L and significant growth inhibition at higher concentrations. 1985 AR226-0911 nmYZ2a39a162ZqV7XdewKx10w 4
This document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on the aquatic invertebrate Daphnia magna, indicating that the test sample FX-3103 consists of 0.96% PFOS among other components, although the specific method and results are not provided. 1985 AR226-0912 3Qvo0MN5aQ3kq1oBmBRq7R99n 5
The document reports on a Microbios Microtox toxicity test conducted on a mixture containing 0.96% perfluorooctanesulfonate (PFOS) and other components, indicating that the EC50 values for the test were greater than 1000 mg/L at both 5 and 15 minutes, suggesting low toxicity for the mixture tested. 1985 AR226-0913 pBeBZDem1EJ3q4X8K7zGqm4Ed 4
The document reports on an activated sludge respiration inhibition test for a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the 30-minute and 3-hour EC50 values were both greater than 1000 mg/L, suggesting low toxicity at the tested concentrations. 1985 AR226-0914 qajdqjr5BY2RVE3Yv9OpEypKk 5
The document reports on a biodegradation test conducted by 3M Company in 1985 for a mixture containing 0.48% PFOS, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks detailed methodology and characterization of the test substance. 1985 AR226-0915 3eYYEDnyM6w3Eb83vrYz0Bdvx 3
The document details an acute toxicity test of a mixture containing 0.48% PFOS on fathead minnows (Pimephales promelas), conducted in 1985, with findings indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incompletely characterized concentrations of impurities. 1985 AR226-0916 vKGJNkOgO7KNLMnpLbpOZv2Y 4
The document reports on a toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) and other components, revealing a 96-hour IC50 value of 576 mg/L for the aquatic plant Selenastrum capricomutum, indicating significant inhibition of algal growth at higher concentrations. 1985 AR226-0917 rBKv4zBGJdZj2XrJNj7kL1qXV 4
The document details an acute toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) conducted on Daphnia magna, indicating that the test sample FX-3104 consists of 0.48% PFOS among other components, although the toxicity data may not accurately reflect the fluorochemical's effects due to impurities. 1985 AR226-0918 ZeDQgD1nDVxVmYqgXMqEBbep 5
The document reports on a Microbics Microtox toxicity test conducted on a mixture containing 0.48% PFOS, indicating that the 5-minute and 15-minute EC50 values were greater than 1000 mg/L, suggesting low toxicity for the tested mixture. 1985 AR226-0919 aJognpZ4zMQv80L816b6NQ5LR 4
The document reports on an activated sludge respiration inhibition test for a mixture containing 0.48% PFOS, conducted using a sample identified as FX-3104, which showed an EC50 greater than 1000 mg/L, indicating low toxicity to the test organisms. 1985 AR226-0920 qdXLvr5xGgJa3EZM7XgJZjoxK 4
This document reports on a biodegradation study of a mixture containing 2.31% perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high chemical oxygen demand (COD) and biochemical oxygen demand (BOD) values, but lacking reliable data quality and characterization of the test substance. 1985 AR226-0921 1e2xDZXLBxYwxLnN1GRgDDY5 9
The document details an acute toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows, indicating no mortality observed over a 96-hour exposure period. 1985 AR226-0922 jgg6eyVo3X2epv89a9XYEJgBp 5
The document reports the results of a Microbios Microtox toxicity test on a mixture containing 2.31% PFOS, produced by 3M Japan, indicating that the EC50 values for both 5-minute and 15-minute exposures were greater than 1000 mg/L, suggesting low toxicity of the mixture. 1985 AR226-0923 ykQqXX1x80g2V95qMkjwqa84r 4
The document reports that cholestyramine significantly enhances the fecal elimination of carbon-14 from ammonium [14C]perfluorooctanoate (PFOA) and potassium [14C]perfluorooctanesulfonate (PFOS) in rats, reducing liver concentrations of carbon-14 compared to control rats. 1984 AR226-0008 wqkx2z33YqQYONgL7MzvNDQ6E 3
The document reports the results of an acute ocular irritation test conducted on the substance T-3493, indicating it is minimally irritating to the eyes of female albino rabbits, with only minimal conjunctivitis observed that resolved within two days. 1984 AR226-0306 yr4YM238MJR6LpDK4KEM1Dp1D 12
The document is a final report from SRI International assessing the mutagenic activity of 3M Company's Compound T-3609 using the Ames Salmonella/microsome assay, concluding that the compound was nonmutagenic and nonrecombinogenic. 1984 AR226-0310 4JgGoNvz3bMbkEKx33YE24a61 18
The document reports on a primary skin irritation test of the substance T-3494 conducted on female albino rabbits at Riker Laboratories, indicating that T-3494 is slightly irritating to the skin with a score of 0.7/8.0. 1984 AR226-0313 bBLZ5689LgQ8R9DB3YoKvgJD3 10
The document reports the results of an acute ocular irritation test conducted on T-3494, indicating it is minimally irritating to the eyes of female albino rabbits, with no significant damage observed. 1984 AR226-0314 b8Ew9Ka5Q0OJkOep94O5dDmZ 12
The document is a final report from SRI International assessing the mutagenic and recombinogenic activity of 3M Company's Compound T-3610 using the Ames Salmonella/microsome assay and the Saccharomyces cerevisiae D3 assay, concluding that Compound T-3610 is nonmutagenic and nonrecombinogenic. 1984 AR226-0316 pmMYr0YkbNn4y7JYZmRm36YmE 18
The document reports on a biodegradation study of N-Ethylperfluorooctanesulfonamide (EtFOSA) conducted by 3M Company, indicating that the substance is not capable of readily biodegrading in aerobic environments, with a 20-day BOD result of less than 940 mg/kg. 1984 AR226-0336 ev3z6Y3JxorZ2dazYvD1E7b5q 4
The document reports on an acute toxicity study conducted by 3M Company in 1984, which found that N-Ethylperfluorooctanesulfonamide (EtFOSA) has a 96-hour LC50 of 34 mg/L for the fish species Pimephales promelas, although the study's reliability is questioned due to issues with sample purity and concentration measurements. 1984 AR226-0339 7Z3vDdVN3Rwd16YrGExxJDE8 5
The document reports on a toxicity study conducted by 3M Company in 1984, which found that N-Ethylperfluorooctanesulfonamide (EtFOSA) has an acute immobilization EC50 of 3.2 mg/L for daphnids, although the study's reliability is questioned due to unmeasured actual concentrations and inadequate sample purity characterization. 1984 AR226-0341 0LdkKGpDkeg0p80zEGX931zkk 5
The document is a final report of a rat teratology study (Project No. 154-161) conducted by Hazleton Laboratories America Inc. for 3M Company, focusing on the effects of a perfluorinated compound on fetal development, with quality assurance inspections and findings documented throughout the study. 1984 AR226-0979 8RbM0Q7qzBnJz6J5bVgMRoo8B 76
The document reports on an acute inhalation toxicity study of T-3607, a perfluorinated compound (specifically perfluorooctyl sulfonyl fluoride), sponsored by 3M Company, which found no mortalities or clinical signs of toxicity in rats exposed to a concentration of 3.74 mg/L for four hours. 1984 AR226-0206 XRqRx8eKXxKqZnxqb17rj1okJ 12
The document reports that a primary skin irritation test conducted on T-3608 at Riker Laboratories, Inc. found it to be non-irritating to the skin of female albino rabbits, with no signs of erythema or edema observed. 1984 AR226-0237 NeJBwVd2dRYppoNRa8ny0ZOGp 10
The document reports on an acute inhalation toxicity study of T-3607 (perfluorooctyl sulfonyl fluoride) conducted by Bushy Run Research Center for 3M Company, finding no mortality or clinical signs of toxicity in rats exposed to a concentration of 3.74 mg/L. 1984 AR226-0206 Jv8w68EVx5jK5bpp55ezRLv0B 12
The document reports that a primary skin irritation test conducted on T-3608 in female albino rabbits at Riker Laboratories, Inc. found it to be non-irritating, with no signs of erythema or edema observed. 1984 AR226-0237 zoeoyr9VgbOdoN1D7gL96pwN6 10
The document reports that cholestyramine significantly enhances the fecal elimination of carbon-14 from ammonium [14C]perfluorooctanoate (PFOA) and potassium [14C]perfluorooctanesulfonate (PFOS) in rats, reducing liver concentrations of these compounds compared to control rats. 1984 AR226-0008 rxV2XvGnyeLyMddzYer1NVrGE 3
The document details a biodegradation test (OECD 301E) for a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample, FC-203 NFP, consists of 1.34% PFOS along with various other components, but notes that the data may not accurately reflect the biodegradability of the fluor 1984 AR226-0739 Qk7ByG6npMZV0BOgm2x3OvyKE 15
The document details an acute toxicity test on fathead minnows (Pimephales promelas) using a mixture containing 1% perfluorooctanesulfonate (PFOS) and various other components, indicating that the data may not accurately reflect the toxicity of the fluorochemical due to incomplete characterization of impurities. 1984 AR226-0839 6RaVOBNvvYZ8kQmpjM4M1ambm 7
The document reports on an activated sludge respiration inhibition test for a mixture containing 1% PFOS, conducted using a sample from 3M, which found no inhibitory effect on the respiration rate of activated sludge at tested concentrations. 1984 AR226-0840 pGgRknwDM9OvwDvLOM8q2ge6 6
The document reports the results of an acute ocular irritation test conducted on the substance T-3493, indicating it is minimally irritating to the eyes of female albino rabbits, with only minimal conjunctivitis observed. 1984 AR226-0306 1eV29wODX7GoJ8d7284rER0m 12
The document is a final report from SRI International detailing the results of in vitro microbiological mutagenicity assays conducted on 3M Company's Compound T-3609, which was found to be nonmutagenic and nonrecombinogenic. 1984 AR226-0310 NNkQ6QE10xQg36zdE1v6rO3z8 18