|
The document reports on a primary skin irritation test of the substance T-3494 conducted on female albino rabbits at Riker Laboratories, indicating that T-3494 is slightly irritating to the skin, with slight erythema observed but no edema.
|
1984 |
AR226-0313
|
rBg8wG2vjQxLvv21Op037p4x7 |
10 |
|
The document reports on an acute ocular irritation test of the substance T-3494 conducted on female albino rabbits at Riker Laboratories, indicating that T-3494 is minimally irritating to the eyes, with only temporary conjunctivitis observed.
|
1984 |
AR226-0314
|
oddQb611JQeJEyQdRMx7qeBD |
12 |
|
The document is a final report from SRI International detailing the results of in vitro mutagenicity assays conducted on 3M Company's Compound T-3610, which was found to be nonmutagenic and nonrecombinogenic in both the Ames Salmonella/microsome assay and the yeast Saccharomyces cerevisiae D3 assay.
|
1984 |
AR226-0316
|
QXdJ8p5ymjeKMaxQB4nQ3x9X6 |
18 |
|
The document reports on a biodegradation study of N-Ethylperfluorooctanesulfonamide (FX-12) conducted by 3M Company, indicating that the substance is not capable of readily biodegrading in aerobic environments, with a 20-day BOD of <940 mg/kg and a COD of 22,000 mg/kg.
|
1984 |
AR226-0336
|
Byz84REnkb7dKKBmMOqzbB5Ok |
4 |
|
The document reports on an acute toxicity study conducted by 3M Company in 1984, which found that N-Ethylperfluorooctanesulfonamide (EtFOSA) has a 96-hour LC50 of 34 mg/L for the fish species Pimephales promelas, although the study's reliability is questioned due to issues with sample purity and concentration measurement.
|
1984 |
AR226-0339
|
dnpgMk9Lb2d5vD1dEo1mwyan0 |
5 |
|
The document reports on a toxicity study conducted by 3M Company in 1984, which found that N-Ethylperfluorooctanesulfonamide (EtFOSA) has an EC50 of 3.2 mg/L for immobilization of daphnids, although the study's reliability is questioned due to unmeasured actual concentrations and inadequate characterization of sample purity.
|
1984 |
AR226-0341
|
NekbJ8qrO1aqV9B1wB6a3rvnD |
5 |
|
The document reports on a solubility screening study conducted by 3M Company in 1984 for perfluorooctanesulfonyl fluoride (FX-8), indicating that it is slightly soluble in water with measured total organic carbon (TOC) values below 2 mg/L across various nominal concentrations, but the study lacks sufficient quality due to uncharacterized purity and indirect measurement methods
|
1984 |
AR226-0374
|
ZJDVnMM0REKBErmGm46XV4MMV |
6 |
|
The document reports on an activated sludge respiration inhibition test conducted by 3M Company, which found that perfluorooctanesulfonyl fluoride (POSF) exhibited no inhibitory effect on respiration at a concentration of 1000 mg/L over a 6.75-minute exposure.
|
1984 |
AR226-0375
|
qep8m6vM7OwjLXqNYw70E9mK |
6 |
|
The document reports on an acute toxicity test of perfluorooctanesulfonyl fluoride (POSF) on the fish species Pimphales promelas, indicating that the 24, 48, and 96-hour LC50 values were all greater than 1000 mg/L, suggesting low toxicity at the tested concentrations.
|
1984 |
AR226-0376
|
MGQOmGj6Z4wMxd1J2YkKQx5M7 |
6 |
|
The document reports on a biodegradation study conducted by 3M Company on the test substance 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate, indicating that it is not capable of readily biodegrading in aerobic environments, with significant biochemical oxygen demand (BOD) results over 20 days.
|
1984 |
AR226-0411
|
MGkgKBQ7Rd6L70y2o08Nr2xBy |
8 |
|
The document reports on an activated sludge respiration inhibition test conducted by 3M Company, which found that the test substance 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate (B1228) exhibited no inhibitory effect on respiration at a concentration of 1000 mg/L after 6.65 minutes of exposure, indicating an EC50 greater than
|
1984 |
AR226-0414
|
dDxjJpVZjjZXbxXxXX7vpeM55 |
4 |
|
The document reports on an acute toxicity study of the perfluorinated compound EtFOSEA (2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate) on fathead minnows, concluding that the 96-hour LC50 is greater than 1000 mg/L, indicating low toxicity at the tested concentrations.
|
1984 |
AR226-0413
|
ybgbop3yozYmG7ZBN7K8wgLBD |
4 |
|
The document reports on an oral teratology study of T-3141CoC, conducted by 3M Commercial Chemical Division, which found that the compound did not cause embryotoxicity or teratogenic effects in pregnant rabbits at doses up to 50 mg/kg/day, although the high dose group experienced significant weight loss.
|
1984 |
AR226-0465
|
gEYr0Bg543yKqd4dd469K1RKJ |
29 |
|
The document reports on the inorganic fluoride test results for personnel from Building 15, indicating no increased levels of inorganic fluoride exposure among the group despite previous concerns related to organic fluorine determinations.
|
1984 |
AR226-0482
|
0LLNVY6BKv0xGnz5yNGzEJwn |
3 |
|
The document discusses concerns regarding increasing blood fluorine levels among employees in Building 15, linked to the handling of organic fluorine compounds, indicating a need for improved protective measures if the trend continues.
|
1984 |
AR226-0483
|
e2YVjvoaM6nMaeBxJNgBR6vg |
4 |
|
The document reports on a respiration inhibition test conducted on 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro, in compliance with OECD Guideline No. 209, sponsored by the Telomer Research Project involving companies such as DuPont
|
1984 |
AR226-1220
|
vVZZ9j8ZX3GOE1ZXJr7EJ26yE |
30 |
|
The document presents data on C-8 (PFOA) levels in drinking water from various locations near the No. 5 outfall, indicating detectable levels in the Lbeck Water District and Little Hocking, while other locations showed non-detectable levels from 1984 to 1988.
|
1984 |
AR226-1410
|
6b06LXONjpNEnNn4EObZg0OZE |
1 |
|
The document reports on an acute toxicity test of 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro conducted on earthworms (Eisenia fetida) according to OECD Guideline 207, sponsored by the Telomer Research Project
|
1984 |
AR226-1429
|
zoaa6bYdJVq0rEY32mpdG3OKa |
33 |
|
The document reports on a solubility screening study conducted by 3M Company in 1984 for perfluorooctanesulfonyl fluoride (FX-8), indicating that it is slightly soluble in water with measured total organic carbon (TOC) values below 2 mg/L across various concentrations, although the study's reliability is questioned due to lack of actual concentration measurements and characterization of
|
1984 |
AR226-0374
|
OwBZ4Laok5doyXJYEZ4E2Zy1 |
6 |
|
The document reports on an activated sludge respiration inhibition test conducted by 3M Company on perfluorooctanesulfonyl fluoride (POSF), indicating that the substance showed no inhibitory effect on respiration at a concentration of 1000 mg/L over a 6.75-minute exposure.
|
1984 |
AR226-0375
|
q3QaO84vXm9bMDzDNZJ98M27E |
6 |
|
The document reports on an acute toxicity test of perfluorooctanesulfonyl fluoride (POSF) on the fish species Pimphales promelas, indicating that the 24, 48, and 96-hour LC50 values were all greater than 1000 mg/L, suggesting low toxicity at the tested concentrations.
|
1984 |
AR226-0376
|
3e7vOLxyooOapb3a01wGkyKE0 |
6 |
|
The document reports on a biodegradation study conducted by 3M Company on the test substance 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate, indicating that it is not capable of readily biodegrading in aerobic environments, with significant biochemical oxygen demand (BOD) results.
|
1984 |
AR226-0411
|
93yLdx9576rodVNn3JNRoX6Oe |
8 |
|
The document reports on an acute toxicity study of the perfluorinated compound EtFOSEA (2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate) on fathead minnows (Pimephales promelas), concluding that the 96-hour LC50 is greater than 1000 mg/L, indicating low toxicity at the tested concentrations.
|
1984 |
AR226-0413
|
6JKa5MJ26JNzrLZZ9jq6794 |
4 |
|
The document reports on an activated sludge respiration inhibition test for the substance 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate (B1228), conducted by 3M Company, which concluded that the substance exhibited no inhibitory effect on respiration at a concentration of 1000 mg/L after 6.65 minutes of exposure.
|
1984 |
AR226-0414
|
KJjqQV8bLDK28v216e6rjJ3Rr |
4 |
|
The document outlines a request to schedule annual C-8 (PFOA) blood tests for EPD Operators in a specific month starting in 1985 to improve efficiency in sample analysis and timely reporting of results.
|
1984 |
AR226-1635
|
wJ6o6o0jqEqMG09vG1b4qL5J |
2 |
|
The document provides an update on the C-8 (perfluorooctanoic acid, PFOA) blood sampling program, indicating that Fine Powder/Dispersion Operators experienced an average 24% drop and FEP Operators a 12% drop in blood C-8 levels over the past 2 to 3 years, based on recent blood sample results.
|
1984 |
AR226-1634
|
2BMYRVLd6kxQVez9rRm8Y1Mb |
22 |
|
The document reports on an oral teratology study of T-3141CoC, sponsored by 3M Commercial Chemical Division, which found that the compound did not cause embryotoxicity or teratogenic effects in pregnant rabbits at doses up to 50 mg/kg/day, although the high dose group experienced significant weight loss.
|
1984 |
AR226-0465
|
vVrqknEGmJVG6OabjYaZgLgqb |
29 |
|
The document reports that inorganic fluoride test results from blood samples of personnel at 3M's Building 15, dating back to 1980 and tested up to November 1983, indicate no increased exposure to inorganic fluoride among the individuals tested.
|
1984 |
AR226-0482
|
dQbp8on7w69r3ykpDB1BORw89 |
3 |
|
The document discusses concerns regarding increasing blood fluorine levels among employees in Building 15, linked to the handling of organic fluorine compounds, and emphasizes the need for improved personal hygiene and engineering controls to mitigate exposure risks.
|
1984 |
AR226-0483
|
EdY2ovpBO2bkJ7EQv6NyZmMvV |
4 |
|
Unreadable document.
|
1984 |
AR226-1984
|
KzRe2OvOwoad5MpEGorr3xO8K |
19 |
|
The document reviews blood data related to C-8 (PFOA) levels among employees at Washington Works, indicating varying percentages of blood contamination across different years and highlighting the challenges in interpreting the data due to personnel changes and historical exposure factors.
|
1984 |
AR226-2010
|
37yKO1gZq004Mp6moQ1JxZwR0 |
5 |
|
The document is a DuPont EMSER report detailing an activated sludge respiration inhibition test conducted on a perfluorinated compound, specifically focusing on compliance with OECD guidelines and Good Laboratory Practices.
|
1984 |
AR226-2730
|
zoJoZa5MBj5eD6rMRyOaQ0DGR |
19 |
|
The document details sampling results for C-8 (PFOA) concentrations in various water sources near the Ohio River, indicating levels above the 0.6 ppb limit in several locations, with CH2MHILL confirming the presence of C-8 in the water.
|
1984 |
AR226-2383
|
xvdprv20gkqNq3bmb6yzB9z1 |
4 |
|
The document provides an update on C-8 (PFOA) levels in water samples from various locations, indicating that recent data confirms previous findings with low concentrations that are not a cause for concern, and no further sampling is planned unless necessary.
|
1984 |
AR226-2385
|
EvpVVYxRYOrNBkLJO2QdXqopN |
2 |
|
This analytical report details the detection of perfluorooctanoate (PFOA) in fifteen water samples, with concentrations ranging from non-detectable to 0.8 ppb, using electron capture gas chromatography.
|
1984 |
AR226-2386
|
50GweyO3eaEXa28OpGX3pez6N |
2 |
|
This analytical report details the detection of perfluorooctanoate (PFOA) in water samples, indicating a detection limit of 0.4 ppb, with some samples showing concentrations of 0.4 ppb and 0.8 ppb.
|
1984 |
AR226-2387
|
oDdO7mvKB6k9raXwOX868nZBr |
2 |
|
The document details water sampling conducted in 1984 near the Washington Works facility, focusing on the presence of perfluorinated compounds, specifically PFOA, in various drinking water sources downstream from the facility.
|
1984 |
AR226-2388
|
b5Qe8a6XzLob9aBjvxNmj8L1y |
2 |
|
The document is a revised draft permit issued by the EPA for E. I. du Pont de Nemours & Company regarding corrective action for hazardous waste management at their facility in Parkersburg, West Virginia, requiring compliance with RCRA regulations.
|
1984 |
AR226-2534
|
QX2g7GzD9ZX7nVO1KEErjpr74 |
49 |
|
The document reports on industrial hygiene surveys conducted at heat-setting operations in the UK and the Netherlands, measuring particulate concentrations related to PFOA exposure, with findings indicating that the sampled concentrations were below the acceptable exposure limit.
|
1984 |
AR226-2913
|
jm3MqN3dLNJ2NndJ2Zjadjnd9 |
13 |
|
The document provides a summary of the physical and toxicological properties of Ammonium Perfluorononanoate (C-9), including its moderate acute oral toxicity, recommended acceptable exposure level (AEL) of 0.01 mg/m3, and the basis for this recommendation based on comparisons to Ammonium Perfluorooctanoate (C-8).
|
1984 |
AR226-3377
|
kLXKonN6jXJKbzzdnXYg2V6J |
2 |
|
The document reports on a biodegradation test (OECD 301E) for a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the data may not accurately reflect the biodegradability of the fluorochemical component due to incomplete characterization of impurities.
|
1984 |
AR226-0739
|
LJxZ9yrNY9mwDgBGGdRG6E1mq |
15 |
|
The document reports on an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1% perfluorooctanesulfonate (PFOS) and various other components, although the study did not provide specific methods or calculate LC50 values due to incomplete characterization of impurities.
|
1984 |
AR226-0839
|
DGvvgkxKBj8GvNK8XrONMzKbn |
7 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 1% PFOS, conducted using a sample identified as L-9235 (FX-601), which showed no inhibitory effect on the respiration rate of activated sludge at tested concentrations.
|
1984 |
AR226-0840
|
6RKdmrYDQBRmakZxZxvgZ0Rm9 |
6 |
|
The document presents data on C-8 (PFOA) levels in drinking water at various distances from the No. 5 outfall, indicating detectable levels in the Lbeck Water District and Little Hocking, while other locations showed no detectable levels from 1984 to 1988.
|
1984 |
AR226-1410
|
a4MkVw59wnebjoKDmGqXwrq0b |
1 |
|
The document discusses a safety evaluation study of the test substance T3351, indicating that while it causes severe maternal toxicity at higher doses, it has minimal adverse effects on fetal development, suggesting that as long as exposure is below toxic levels for adults, embryonic development remains unaffected.
|
1983 |
AR226-0015
|
5K4o7pN0aXKnrpGragEjqypR |
2 |
|
This is a final report from Hazleton Laboratories America, Inc. for a Rat Teratology Study (Project No. 154-160) submitted to 3M Company on December 19, 1983, detailing the study's methodology, results, and quality assurance inspections.
|
1983 |
AR226-0014
|
zoYQkr5OLx6OMOQr6Zp5nkgG6 |
83 |
|
The document reports on a study conducted by Riker Laboratories, Inc. from October 1980 to June 1981, focusing on the metabolism of carbon-14 labeled N-Ethyl FOSE, a perfluorinated compound, in animal subjects, detailing methods of dosing, sample collection, and radiometric analyses.
|
1983 |
AR226-0979
|
GKz8daLLbMwG6n9b0RprKnkN4 |
21 |
|
The document is a final report of a pilot rat teratology study (Project No. 154-159) conducted by Hazleton Laboratories America, Inc. for 3M Company, focusing on the effects of a test compound on maternal and fetal outcomes.
|
1983 |
AR226-0979
|
DGxkdbpaL3Jeo8ggpYM76YD9n |
50 |
|
The document reports on an acute ocular irritation test of T-3421, a substance tested on female albino rabbits at Riker Laboratories, indicating that T-3421 is moderately irritating to the unwashed eye and mildly irritating under limited contact conditions, with various levels of irritation subsiding over time.
|
1983 |
AR226-0211
|
zo86dmLo7d7D9MOvv58NkGLwR |
15 |
|
The document reports on a primary skin irritation test conducted on T-3421 at Riker Laboratories, which found that T-3421 is moderately irritating to the skin of female albino rabbits, with mild erythema and edema observed after a one-day occluded contact period.
|
1983 |
AR226-0212
|
YDGOXKEMVz1ZVqd9NXoB0BXm0 |
10 |
|
The document reports on a primary skin irritation test of the substance T-3421, conducted on female albino rabbits at Riker Laboratories, indicating that T-3421 is moderately irritating to the skin.
|
1983 |
AR226-0212
|
b5jp8yV7xyyMkyrbXwJbja3no |
10 |
|
The document reports the results of an acute ocular irritation test for the substance T-3421 conducted on female albino rabbits, indicating that T-3421 is moderately irritating to the unwashed eye and mildly irritating under limited contact conditions, with various levels of corneal opacity and conjunctivitis observed during the evaluations.
|
1983 |
AR226-0211
|
2J7JXka84Eee8JvnNmwQyN6dg |
15 |
|
This is a letter from Dr. E. Marshall Johnson at Jefferson Medical College to Mr. William C. McCormick at 3M, providing a review of a developmental toxicity study on T3351, highlighting its safety for embryonic development despite maternal toxicity observed at higher doses.
|
1983 |
AR226-0015
|
dYnVr7DD64O3yq0NoNdBve8Q |
2 |
|
This is a final report from Hazleton Laboratories America, Inc. for a Rat Teratology Study (Project No. 154-160) submitted to 3M Company on December 19, 1983, detailing the study's methodology, results, and quality assurance inspections.
|
1983 |
AR226-0014
|
baBXpm8ZDvj935e3vD0nOv6pD |
83 |
|
The document details a biodegradation test (OECD 301E) conducted on a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the test sample is FC-203, which consists of 1.34% PFOS among other substances, but notes that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization
|
1983 |
AR226-0712
|
MJqjxMrOaLwJ2OD7z5g6pBkqV |
14 |
|
The document details a biodegradation test (OECD 301 E) conducted on a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample FC-203 consists of 1.34% PFOS along with various other components, and notes that the data may not accurately reflect the degradation potential of the fluorochemical due to incomplete
|
1983 |
AR226-0713
|
dQb922mGDJKdKvk50ZzeKe2JG |
23 |
|
The document details an activated sludge respiration inhibition test conducted on a mixture containing 1.0% perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the data may not accurately reflect the inhibition caused by the fluorochemical component due to impurities.
|
1983 |
AR226-0831
|
jVLNnvbqz31m4rbgQRoezvrO |
4 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0833
|
gDbkqjb1G0XJo546aEqDNrRwe |
4 |
|
The document describes an activated sludge respiration inhibition test conducted on a mixture containing 1.0% PFOS, produced by 3M, to assess its impact on oxygen consumption, although the results may not accurately reflect the inhibition due to impurities in the test sample.
|
1983 |
AR226-0832
|
rpjdVyDRJ3vqJLy6O5mkOJVXq |
4 |
|
The document details an acute toxicity test on a mixture containing 1.0% PFOS conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0834
|
QMmLo96p2M1zqmpJJoJmerzE4 |
4 |
|
The document reports on an acute toxicity test of a mixture containing 1.0% PFOS conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0835
|
QgMqKoVmKdpjXgZZGVeXR0qqR |
4 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0836
|
85a6R5jEOYpDQQn9r5yQQdgkd |
4 |
|
The document provides an overview of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), including its identity, physical characteristics, and mentions that robust summaries of individual studies are being submitted by 3M Company, while some older studies are not summarized due to the existence of newer research.
|
1983 |
AR226-0365
|
n219X55VLYZnymaDv1gz1Qxz |
36 |
|
The document reports on a study conducted by Riker Laboratories Inc. on the absorption, biotransformation, tissue distribution, and elimination of Carbon-14 labeled N-Ethyl FOSE (2-N-ethyl perfluorooctanesulfonamido ethanol) in animals after administration in feed.
|
1983 |
AR226-0965
|
wrwXG3p7rVgrnM5m6pV6LN7do |
57 |
|
The document reports on a primary skin irritation test conducted on T-3371, a substance tested at Riker Laboratories, which resulted in irreversible tissue damage and severe irritation in female albino rabbits after various contact periods.
|
1983 |
AR226-0424
|
kvO5xzXoE8KNgEDn3VwkBORV |
12 |
|
This document reports that hormonal changes during pregnancy do not affect the rate of elimination of carbon-14 from ammonium C-perfluorooctanoate in pregnant rats, with nearly all carbon-14 excreted via urine within 24 hours, indicating no accumulation in tissues during repeated dosing in teratology studies.
|
1983 |
AR226-0458
|
ZnM9vZrRYOYE8XdGBRe9Nrw4d |
6 |
|
The document is a technical report summary from 3M Company regarding the identity and characterization of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), including remarks on its purity and the status of related studies.
|
1983 |
AR226-0365
|
v69NVYY4gm7kmMEBzg00rV12w |
36 |
|
The document reports on a primary skin irritation test conducted on T-3371, a substance evaluated for its potential to cause irreversible skin damage in female albino rabbits, resulting in moderate erythema, edema, and severe irritation without achieving the required endpoint.
|
1983 |
AR226-0424
|
bykLeO5peadpaDpvwq0LKXgd6 |
12 |
|
The document is a recommendation from Bruce W. Karrh, M.D. of E.I. du Pont de Nemours & Company to proceed with FC-143 blood tests on employees at the F&F plant, specifically those in Teflon-related jobs, following a previous letter dated April 8, 1982.
|
1983 |
AR226-1626
|
xzy7ZejeEJgz6Br3pxDNGqmk6 |
1 |
|
The document reports a statistically significant drop in blood C-8 (PFOA) levels among TEFLON Fine Powder/Dispersion and FEP Operators, indicating a 13% decrease over two years, with average levels of 5.5 ppm and 1.2 ppm respectively.
|
1983 |
AR226-1627
|
peymZdrV1kakR53RQoEGzO9od |
5 |
|
The document reports the analysis of blood samples from Tralee Park employees for perfluorooctanoate (PFOA), revealing concentrations of 0.17 and 0.15 µg/g blood, using gas chromatography.
|
1983 |
AR226-1628
|
wKbBYL05RDwg9MRMzdjrj5Qo |
2 |
|
This document provides detailed blood C-8 (PFOA) level data for employees at E.I. du Pont de Nemours Company's Washington Works who have not worked in the Fluoropolymers Division, indicating that blood C-8 levels are low and reach equilibrium in less than a year.
|
1983 |
AR226-1631
|
71EppmgRdb5ma68bVJOoQOgkV |
2 |
|
The document reports a study conducted by Riker Laboratories, Inc. on the excretion of carbon-14 from ammonium C-perfluorooctanoate in pregnant rats, finding that hormonal changes during pregnancy do not affect the elimination rate, with nearly all carbon-14 excreted via urine within 24 hours for both pregnant and nonpregnant rats.
|
1983 |
AR226-0458
|
8OQ9LNBLkY3BYkZO0djX1pLVa |
6 |
|
Unreadable document.
|
1983 |
AR226-1983
|
6RB1DxzJR72oJ8DjBz1pdNwEg |
2 |
|
The interoffice memorandum discusses test results for C8 (likely PFOA or PFOS) in water samples from various locations, indicating concentrations ranging from below detection limits to 10.8 ppb.
|
1983 |
AR226-2405
|
6BM9eyMVON0q47n1R8GgdMm46 |
1 |
|
The document provides an overview of Telomer B Carbamate, including its chemical structure, physical properties, toxicity data, and recommended acceptable exposure limits (AEL) based on studies conducted by DuPont, indicating a low acute toxicity profile and a recommended AEL of 1 mg/m³ for respirable particulate.
|
1983 |
AR226-3383
|
v6pdn64eqwK7VBnkwgQw4D6dR |
2 |
|
The document details a biodegradation test (OECD 301E) for a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample, FC-203, consists of 1.34% PFOS along with various other components, but notes that the data may not accurately reflect the toxicity of the fluorochemical due to incomplete
|
1983 |
AR226-0712
|
p8QxZMQ9wKX4QD8LYJN8KmbB |
14 |
|
The document details a biodegradation test (OECD 301 E) conducted on a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample FC-203 consists of 1.34% PFOS and various other components, with results based on the percentage of dissolved organic carbon removal.
|
1983 |
AR226-0713
|
ymqYgLz5kQdLRj4eyJ4Qe0p8n |
23 |
|
The document details an activated sludge respiration inhibition test conducted on a mixture containing 1.0% perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the data may not accurately reflect the inhibition caused by the fluorochemical component due to impurities.
|
1983 |
AR226-0831
|
Nez7477YXe6XjOZ1vRO0LgKpR |
4 |
|
The document details an activated sludge respiration inhibition test conducted on a mixture containing 1.0% PFOS, produced by 3M, indicating that the test sample's composition may affect the accuracy of the results regarding PFOS's inhibition effects.
|
1983 |
AR226-0832
|
7OE4Gyaaa5LpXj7Lmo2w3Q4kR |
4 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% PFOS, produced by 3M, which showed no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0833
|
g2kday5qbdr48nGyEakxw5OkG |
4 |
|
The document reports on an acute toxicity test of a mixture containing 1.0% PFOS conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0834
|
DMLr2G4Bnkny85VYNXqzaqvoa |
4 |
|
The document reports on an acute toxicity test of a mixture containing 1.0% PFOS, conducted on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0835
|
3bkr7G2z5ge9a0007gyr90Na |
4 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on fathead minnows (Pimephales promelas), indicating no mortality at the highest concentration tested over a 96-hour exposure period.
|
1983 |
AR226-0836
|
gaLrGm2ZrQ8g4oxL8wjORGOrN |
4 |
|
The document is a recommendation from Bruce W. Karrh, M.D. of DuPont to proceed with blood tests for FC-143 (a perfluorinated compound) on employees involved in Teflon production, indicating that further testing may not be necessary after initial analyses.
|
1983 |
AR226-1626
|
3J5jj850zyL3DYjdO38ZDm743 |
1 |
|
The document is an analytical report confirming that FM-3924, a perfluorinated compound, meets quality control specifications and is stable, as analyzed for Riker teratology study #0681TR0362.
|
1982 |
AR226-0279
|
wgxDnZmyxxykrwyb1x1Gabj8d |
2 |
|
The internal correspondence details the analytical results of FM-3924, a perfluorinated compound, confirming its structure and composition for Riker's teratology study, with specific findings on isomer distribution and elemental analysis.
|
1982 |
AR226-0286
|
zo6bxEeJR6r2B3q4ngkQeLaE7 |
2 |
|
The document discusses a review of anatomical specimens related to a study on the effects of a test substance, revealing that previously reported abnormalities in fetal rat eyes were actually normal findings, indicating potential errors in the original study's conclusions.
|
1982 |
AR226-0017
|
YrvDkeVjq1pjxdwgR6md42V9n |
2 |
|
The document is a final report from SRI International assessing the mutagenic and recombinogenic activity of 3M Company's Compound T-3290CoC using in vitro assays, concluding that the compound was neither mutagenic nor recombinogenic.
|
1982 |
AR226-0222
|
MJ5M83JV6yeRJONN2ag2vy7D7 |
16 |
|
The document reports a water solubility calculation for Decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2070), produced by 3M Company, indicating a solubility of 250 g/L, although the reliability of the calculation is questioned due to lack of validation.
|
1982 |
AR226-1030
|
RJ9dw21kmegOB8ooz9YZaEjLX |
2 |
|
This document summarizes a toxicity study on perfluorooctanesulfonate (PFOS) conducted by Beak Consultants for Panarctic Oils, reporting an acute 48-hour EC50 value for Daphnia magna of 58 to 67 mg/L, although the study's reliability is limited due to unmeasured actual concentrations and uncharacterized sample purity.
|
1982 |
AR226-1030
|
QkQeYpXg57nevB7ek25wqqknL |
1 |
|
The document details an acute toxicity test conducted in 1982 on the fish species Pimephales promelas (fathead minnow) using a mixture identified as PFOSAA (perfluorooctanesulfonylamido(ethyl)acetate) produced by 3M, which showed an LC50 value greater than the highest concentration tested, indicating low toxicity.
|
1982 |
AR226-1030
|
6w2nREpvGrBbgwLR0QE9N80kR |
3 |
|
The document reports on an acute toxicity test of the perfluorinated compound Perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) conducted on fathead minnows (Pimephales promelas), indicating that the LC50 value was greater than the highest concentration tested.
|
1982 |
AR226-1030
|
X8O6oG6q0NL0vBM3Bj4rwGRm4 |
3 |
|
The document details a biodegradation test of a mixture containing perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) produced by 3M, indicating that the results for the 28-day Chemical Oxygen Demand (COD) were invalid and do not accurately reflect the degradation potential of the fluorochemical component.
|
1982 |
AR226-1030
|
w45j8bQ9ZVydL7jmrZLR4Lp4 |
3 |
|
The document details a biodegradation study of perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) produced by 3M, indicating a Chemical Oxygen Demand (COD) of 280,000 mg/kg and a 28-day Biochemical Oxygen Demand (BOD) of 18,900 mg/kg, suggesting limited biodegradability.
|
1982 |
AR226-1030
|
wq410EwZ1YbkxLQm9op23q8Eo |
2 |
|
The document reports on a 1982 acute toxicity test conducted by 3M Company on a mixture containing perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA), indicating that it does not inhibit the respiration rate of activated sludge at a concentration of 1000 mg/L.
|
1982 |
AR226-1030
|
6B8doe3ExoLnkaZ0vXLLKJvxE |
2 |
|
The document is a final report from SRI International assessing the mutagenic and recombinogenic activity of 3M Company's Compound T-3290CoC using in vitro assays, concluding that the compound was neither mutagenic nor recombinogenic.
|
1982 |
AR226-0222
|
req3nxDzoBm7yoY8L1N7NJqjV |
16 |
|
The document discusses a review of anatomical specimens related to a study on the effects of a test substance, indicating that previously reported abnormalities in fetal rat eyes were misidentified and that the evaluation process lacked proper controls, which undermines the validity of the findings.
|
1982 |
AR226-0017
|
K6np9KvxXKmxJYMV6m9oKG4R0 |
2 |
|
This document presents a biodegradation study of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1982, reporting high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking detailed methodology and data reliability.
|
1982 |
AR226-0685
|
q3Yxa5m58dD56Jq6RDL3dNVpR |
3 |
|
The document details an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using juvenile Pimephales promelas, with specific test conditions and methods outlined, although it notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1982 |
AR226-0686
|
5kL9neJO6Bd38ZjgBjQBwo5v4 |
12 |