|
The document details a toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the OECD Guideline 201 method, focusing on its effects on the aquatic plant species Selenastrum capricomutum, with the test sample identified as FC-3003.
|
1997 |
AR226-0886
|
7Mzq4YQvjpbpdkLjOaQjEnnzg |
11 |
|
The document details an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on juvenile fathead minnows (Pimephales promelas) using OECD guidelines, indicating that the test sample was a mixture with various components and noting that the data may not accurately reflect the toxicity of the fluorochemical component.
|
1997 |
AR226-0887
|
nkBeOgGzakkQMXBp8vpGKKmR6 |
4 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1% perfluorooctanesulfonate (PFOS) and other components, following OECD Guideline 203, with results indicating the need for caution due to the presence of impurities in the test sample.
|
1997 |
AR226-0888
|
7RLLqKvoBQYkbZLavj2y65nao |
11 |
|
The document is a quality assurance statement for a chromosomal aberration study of Sample D-1 conducted by the Kashima Laboratory of Mitsubishi Chemical Safety Institute, sponsored by Sumitomo 3M Limited, confirming adherence to GLP standards.
|
1996 |
AR226-0308
|
B5b4g916YXQKwMpn5dVanEw4E |
17 |
|
The document is a final report on a mutagenicity test of T-6295 conducted by Coming Hazleton Inc. for 3M, which utilized an in vivo mouse micronucleus assay to evaluate the potential mutagenic effects of the substance.
|
1996 |
AR226-0130
|
kbg91O7Eea8LmKV75vxyJLDV |
39 |
|
The document is a final report from Hita Research Laboratories, sponsored by Sumitomo 3M Limited, detailing a bacterial reverse mutation test (Study Code K01-1802) conducted on a substance referred to as T-1, in compliance with Japanese toxicity investigation standards.
|
1996 |
AR226-0136
|
3ez24K33M7DV511wJZLN770x3 |
29 |
|
This analytical report by Advanced BioAnalytical Services, Inc. investigates the in vitro metabolism of perfluorinated compounds T-6292, T-6293, T-6294, and T-6295 using rat and human hepatocytes with advanced LC/MS techniques.
|
1996 |
AR226-0328
|
5LezL7xBgavz5aaL1K7anQndD |
45 |
|
The document is a final report on a mutagenicity test conducted by Coming Hazleton Inc. for 3M, measuring chromosomal aberrations in Chinese hamster ovary (CHO) cells, with compliance to Good Laboratory Practice regulations and no significant deviations reported.
|
1996 |
AR226-0979
|
MobK1Q4QXdmR7yzn89E4e0JEx |
41 |
|
The document is a final report on a mutagenicity test of a substance identified as T-6358 conducted by Corning Hazleton Inc. using an in vivo mouse micronucleus assay, submitted to 3M, and completed on May 14, 1996, confirming compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0979
|
71BpL02Ob0EEZ7R00k5kjmgoj |
36 |
|
The document is a final report from Hita Research Laboratories on a bacterial reverse mutation test for a chemical identified as u-1, sponsored by Sumitomo 3M Limited, conducted in compliance with Japanese toxicity investigation standards.
|
1996 |
AR226-0221
|
2jdeEwxaJjQojeVkd774n87Z6 |
23 |
|
The document is a final report of a mutagenicity test conducted by Corning Hazleton on a substance (not specified) using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay, submitted to 3M, and confirms compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0232
|
N2g1vm7yweaBejDjE7G4MRvbD |
30 |
|
The document is a final report on a mutagenicity test of a substance identified as T-6357, conducted by Corning Hazleton Inc. using an in vivo mouse micronucleus assay, submitted to 3M, and completed on April 23, 1996, confirming compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0233
|
xjeY61nK8ReZ6m9r58e9mrQNJ |
27 |
|
The document is a final report on a mutagenicity test of T-6294 conducted by Corning Hazleton Inc. using an in vivo mouse micronucleus assay, submitted to 3M, and confirms compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0239
|
Dv1bvgzN5ZxmG5Zj7d6N3egzo |
36 |
|
The document details an acute toxicity study of perfluorooctanoic acid, tetrabutylammonium salt (PFOA tetrabutylammonium salt), conducted on Daphnia magna, indicating that the test sample was a mixture with incompletely characterized concentrations of impurities, and the study followed U.S. EPA guidelines.
|
1996 |
AR226-1030
|
3N922b9e1O67mjr3krkO091qx |
4 |
|
The document details a toxicity test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), conducted on the aquatic plant Selenastrum capricornutum, using U.S. EPA-TSCA Guideline methods to assess algal cell counts and growth rates over a 96-hour exposure period.
|
1996 |
AR226-1030
|
1Qbx1vYgd8bzyjBDDo7rVJjka |
4 |
|
The document is a final report of a mutagenicity test conducted by Corning Hazleton Inc. on an in vivo mouse micronucleus assay for 3M, ensuring compliance with Good Laboratory Practice regulations and confirming no significant deviations that would affect the study's integrity.
|
1996 |
AR226-0252
|
oeEgo6vNmYg7wxJna0aExODNR |
37 |
|
The document is a final report from Hita Research Laboratories detailing a bacterial reverse mutation test of a substance (designated as u-1) sponsored by Sumitomo 3M Limited, conducted in compliance with Japanese toxicity investigation standards.
|
1996 |
AR226-0221
|
4ap6KnNQVgm60pmjj16Ob2rnG |
23 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton Inc. using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay to evaluate the mutagenic potential of a substance, with the study conducted in compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0232
|
J3VE76Nzmdx8xrEDDyNyxwpOB |
30 |
|
The document is a final report on a mutagenicity test of a substance identified as T-6357, conducted by Corning Hazleton Inc. for 3M, using an in vivo mouse micronucleus assay to assess potential genetic toxicity.
|
1996 |
AR226-0233
|
zn7rzZkGaQgDV8rLBvo4Qyp0 |
27 |
|
The document is a final report of a mutagenicity test on T-6294 conducted by Corning Hazleton Inc. for 3M, using an in vivo mouse micronucleus assay to assess the potential mutagenic effects of the substance.
|
1996 |
AR226-0239
|
7ORDyg4OaV8nn6NdbeLMerRoe |
36 |
|
The document is a final report of a mutagenicity test on PFOA conducted by Corning Hazleton Inc. for 3M, detailing compliance with Good Laboratory Practice regulations and quality assurance inspections.
|
1996 |
AR226-0252
|
Nez6m3xmkpNOnrkLnvaD3Q5ow |
37 |
|
The document is a final report of a mutagenicity test on T-6295 conducted by Coming Hazleton Inc. for 3M, using an in vivo mouse micronucleus assay to evaluate the potential mutagenic effects of the substance.
|
1996 |
AR226-0130
|
a5bwq1ErY2az1OJ0m3O1aZQX |
39 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by Pace Analytical Services for 3M Company, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks detailed methodology and characterization of the sample.
|
1996 |
AR226-0692
|
qkRmdRJp0DrR4gpGd2EyBrBdK |
7 |
|
The document is a final report from Hita Research Laboratories on a bacterial reverse mutation test of a substance referred to as T-1, sponsored by Sumitomo 3M Limited, conducted in compliance with Japanese toxicity investigation standards.
|
1996 |
AR226-0136
|
4aEJgykrQLBD4k4ZG8x69m3NQ |
29 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks reliable conclusions due to insufficient method description and characterization of the inoculum.
|
1996 |
AR226-0848
|
dQ3me8JQemE30JO7x8k7XL7Zb |
9 |
|
The document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on juvenile golden orfe fish, revealing a 96-hour LC50 value of 58 mL/L.
|
1996 |
AR226-0849
|
qdy4j0aBV3g3oqLO3892z4OJM |
10 |
|
The document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) tested on Daphnia magna, revealing a 24-hour EC50 value of 64 mL/L for the mixture.
|
1996 |
AR226-0851
|
YDRyLJYyx3wgpgdLwwkKJM23D |
10 |
|
The document reports on a TTC test conducted by 3M Company on a mixture containing 1.30% PFOS, indicating that exposure concentrations between 0.1 and 10 mL/L showed results comparable to the blank control, but the study lacks detailed descriptions and data quality is rated as Klimisch ranking 3.
|
1996 |
AR226-0852
|
Rjw5MwKD0b5262X9jajMrmRX |
10 |
|
The document reports on an Activated Sludge Respiration Inhibition Test (MITI Test) conducted on a mixture containing 1.30% PFOS, revealing a 28-day biological oxygen demand of 82.5%.
|
1996 |
AR226-0853
|
RaMaw1RRvrnL0jaxmBNgNy4mE |
10 |
|
The document details a Microbics Microtox toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) as part of the test substance FC-603EF, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1996 |
AR226-0854
|
Mob49Qak54V8GjoX55VMxDDxz |
9 |
|
The document describes an activated sludge respiration inhibition test conducted on a mixture containing 1.30% PFOS, assessing its acute toxicity using OECD Guideline 209, with results indicating potential inaccuracies due to the presence of impurities.
|
1996 |
AR226-0855
|
gNNpzOLkOey1zN3O6w5229DJ |
10 |
|
This document details an acute toxicity test of a PFOS-containing mixture (FC-603EF) on Daphnia magna, conducted under OECD Guideline 202, with findings indicating the need for careful interpretation due to the presence of impurities in the test sample.
|
1996 |
AR226-0856
|
RqBaBOj9Mgp12gKDepMxEOvV |
10 |
|
The document details a toxicity test conducted on a mixture containing 1.30% perfluorooctanesulfonate (PFOS) using the OECD Guideline 201 method to assess its impact on the growth of the aquatic plant species Selenastrum capricornutum over a 96-hour exposure period.
|
1996 |
AR226-0857
|
2jQyZbpKZzG19x8ye6KoZpMa6 |
12 |
|
The document is a quality assurance statement for a chromosomal aberration study of Sample D-1 conducted by Mitsubishi Chemical Safety Institute Ltd. for Sumitomo 3M Limited, adhering to GLP standards.
|
1996 |
AR226-0308
|
06Ew28g9dka4JrGrevxLOEnQx |
17 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M Company, indicating high Chemical Oxygen Demand (COD) values but noting that the sample's purity was not properly characterized, which may affect the accuracy of the biodegradation potential assessment.
|
1996 |
AR226-0890
|
v6LDZjxzVpKdQ6momeD2Yeqrb |
6 |
|
The document reports on a toxicity test of a PFOS-containing mixture (FC-3017) on the aquatic plant species Selenastrum capricornutum, indicating that the study followed OECD guidelines but lacked detailed data on the toxicity results due to incomplete characterization of the test substance.
|
1996 |
AR226-0895
|
n9VkrjOqa2qmBj28wvYpJJGp1 |
7 |
|
This analytical report by Advanced Bioanalytical Services investigates the in vitro metabolism of compounds T-6292, T-6293, T-6294, and T-6295 using rat and human hepatocytes with advanced LC/MS techniques, prepared for the 3M Medical Department.
|
1996 |
AR226-0328
|
0qzOEwo74V77Kd4kqgw23LJZO |
45 |
|
The document reports on a study of 51 employees with the highest blood levels of C-8 (perfluorooctanoic acid), indicating minimal evidence of disease attributable to C-8, with some elevations in liver enzymes and a few cases of kidney disease, but no definitive conclusions due to lack of controlled studies.
|
1996 |
AR226-1307
|
jyvkNYO19w9nq8qn87EMMQ2B2 |
6 |
|
The document is a final report on a mutagenicity test of T-6564 conducted by Coming Hazleton Inc. for 3M Corporation, using an in vivo mouse micronucleus assay to assess the potential mutagenic effects of the substance.
|
1996 |
AR226-0430
|
By070g964dLojDb7rvqJ5rggj |
26 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, measuring chromosomal aberrations in Chinese hamster ovary (CHO) cells using the substance T-6564, with findings compliant with Good Laboratory Practice regulations.
|
1996 |
AR226-0431
|
x5bLLy8ROq22yo142VX4LxGeb |
30 |
|
The document is a final report of a mutagenicity test conducted by Coming Hazleton Inc. for 3M Corporation, assessing the mutagenic potential of a substance identified as T-6564 using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay, with findings indicating compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0432
|
kVOdo9mBNQdJrGNnoR1Q2x7J |
34 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, measuring chromosome aberrations in human whole blood lymphocytes related to the substance T-6342.
|
1996 |
AR226-0433
|
MoGE6nEoexgJEVzr7g3kezZ4k |
29 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, assessing chromosomal aberrations in Chinese hamster ovary (CHO) cells related to the substance T-6342.
|
1996 |
AR226-0434
|
kmBvpgbYdkb0LbLwox5yN9nDb |
35 |
|
This letter from the Robert A. Taft Laboratories addresses a Health Hazard Evaluation regarding employee exposure to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) at the 3M Corporation in Cottage Grove, Minnesota, noting that no health effects were observed despite concerns over elevated blood fluoride levels and the implementation of engineering controls and personal
|
1996 |
AR226-1350
|
G639E4gvM3ByqzdxGqQxomY6q |
6 |
|
The document discusses a study by Gilliland and Mandel published in the American Journal of Industrial Medicine, which evaluates the effects of serum perfluorooctanoic acid (PFOA) on hepatic enzymes, lipoproteins, and cholesterol in 115 occupationally exposed workers, finding no significant clinical hepatic toxicity at the measured PFOA levels, although it suggests PFOA may exacerbate obesity
|
1996 |
AR226-0475
|
YKrppk55rVoVDJGN8d1Jve80 |
8 |
|
The document reports the results of a Microbios Microtox toxicity test conducted on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), indicating that the 30-minute EC50 value was 730 mg/L, suggesting low acute toxicity to the test organism Photobacterium phosphoreum.
|
1996 |
AR226-0521
|
LpOZobN0vED3BQ4q5gYbEbxqz |
6 |
|
The document reports the results of a Microbios Microtox toxicity test on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), indicating an EC50 value of 4460 mg/L at 5 minutes and 3360 mg/L at 15 minutes, although the test sample's purity was not sufficiently characterized.
|
1996 |
AR226-0522
|
VG1mbwXZeOgJwgzJxYBqyZ5mN |
8 |
|
The document details a Microtox toxicity test conducted on a mixture containing perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically the test sample FC-1015-X, to evaluate its toxicity using Photobacterium phosphoreum, although the purity of the sample was not sufficiently characterized.
|
1996 |
AR226-0523
|
zzqo96p9wBqkzye1Y6Z94za30 |
6 |
|
The document describes an activated sludge respiration inhibition test conducted on perfluorooctanoic acid (PFOA) ammonium salt, specifically the FC-1015-X sample, to assess its toxicity compared to a reference substance, 3,5-dichlorophenol, using activated sludge from a wastewater treatment plant.
|
1996 |
AR226-0524
|
GmOYDNaxqnEvpgbm8pmOQ6NQm |
9 |
|
The document reports on a toxicity test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically examining its effects on the aquatic plant species Selenastrum capricornutum using a mixture from the 3M product FC-1015, with findings indicating potential toxicity but noting that the purity and characterization of the test sample were incomplete.
|
1996 |
AR226-0526
|
Yj4oEGwoD2YQVp43wJV4J4e2E |
23 |
|
The document details an acute toxicity test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically the FC-1015 sample, on Daphnia magna, conducted under USEPA guidelines, with findings indicating that the toxicity data may not accurately reflect the test substance due to impurities in the sample.
|
1996 |
AR226-0527
|
EvbvnxwZxmKy8DKwDg7R82wzx |
28 |
|
The document details an acute toxicity test of perfluorooctylsulfonate (PFOS) conducted on the fish species Pimephales promelas, using a test sample from 3M, with specific conditions and methods outlined for the 96-hour exposure period.
|
1996 |
AR226-0534
|
oDbVjVDG5NOVa89JXMVrykx5X |
11 |
|
The document details an acute toxicity test of perfluorooctylsulfonate (PFOS) on the aquatic invertebrate Daphnia magna, conducted by 3M in 1996, using a mixture of the test substance in water, with monitoring of various environmental parameters.
|
1996 |
AR226-0535
|
gEgVDwdDjo010Q4GDQyoJxDRQ |
11 |
|
The document details a Microtox toxicity test conducted on a mixture containing perfluorooctylsulfonate (CAS # 251099-16-8) produced by 3M, indicating that the test sample was a 2-phase dispersion and involved Vibrio fischeri as the test organism, although no adjustments were made for the actual concentration of the test substance.
|
1996 |
AR226-0538
|
KG3DQD4NKXBXdBqK8p2KxNmex |
7 |
|
The document is a final report of a mutagenicity test on T-6564 conducted by Coming Hazleton Inc. for 3M Corporation, utilizing an in vivo mouse micronucleus assay to assess the potential mutagenic effects of the substance.
|
1996 |
AR226-0430
|
aBb3Oxdb0oNJ89KV9kpmXrVBY |
26 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton Inc. for 3M Corporation, measuring chromosomal aberrations in Chinese hamster ovary (CHO) cells using the substance T-6564, with compliance to Good Laboratory Practice regulations.
|
1996 |
AR226-0431
|
x3qqNgjQBZ6a5eGXGKrjwDbg |
30 |
|
The document is a final report on a mutagenicity test of a substance (T-6564) conducted by Coming Hazleton Inc. for 3M Corporation, using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay, which was completed in compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0432
|
gb01QkaVpG6767OmmqVnM1aGQ |
34 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, measuring chromosome aberrations in human whole blood lymphocytes using the substance T-6342, with the study completed on November 1, 1996, and found to comply with Good Laboratory Practice regulations.
|
1996 |
AR226-0433
|
Yay5Yp6kN6b75BJ5M3KM7GyN |
29 |
|
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, measuring chromosomal aberrations in Chinese hamster ovary (CHO) cells related to the substance T-6342.
|
1996 |
AR226-0434
|
JJnDbD4JB8gNQ0z6m9bXrDXK6 |
35 |
|
The document discusses a meeting scheduled for December 6, 1996, involving Rik Brandenburg and representatives from Hoechst and ICI to collaborate on analytical methods for determining the migration of C-8 (PFOA) from PTFE-coated pans into food simulants, addressing challenges in measuring migration into olive oil.
|
1996 |
AR226-1665
|
71wwRM6O7EGoD75eV5Eomdba8 |
1 |
|
The document discusses a study by Gilliland and Mandel that evaluates the effects of serum perfluorooctanoic acid (PFOA) on hepatic enzymes, lipoproteins, and cholesterol in 115 occupationally exposed men, finding no significant clinical hepatic toxicity at measured PFOA levels, although it suggests PFOA may interact with obesity and alcohol effects on liver function, with subsequent studies
|
1996 |
AR226-0475
|
rxNb854pX1m9q89MBwJZoqREV |
8 |
|
The document reports the results of a Microbios Microtox toxicity test conducted on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), indicating that the 30-minute EC50 value was 730 mg/L, suggesting low acute toxicity to the test organism Photobacterium phosphoreum.
|
1996 |
AR226-0521
|
2yergERkgBrE81mBO3XyRkj6 |
6 |
|
The document details a Microtox toxicity test conducted on a mixture containing perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically the test sample FC-1015-X, to evaluate its toxicity using Photobacterium phosphoreum, although the purity of the sample was not sufficiently characterized.
|
1996 |
AR226-0523
|
3Q6XyDabbE152mdrnDk1oYmj0 |
6 |
|
The document reports the results of a Microbios Microtox toxicity test on perfluorooctanoic acid ammonium salt (PFOA ammonium salt), indicating an EC50 value of 4460 mg/L at 5 minutes and 3360 mg/L at 15 minutes, although the test sample's purity was not sufficiently characterized.
|
1996 |
AR226-0522
|
Rj55pZjVLMy45y0eoLZvXLQQ7 |
8 |
|
The document describes an activated sludge respiration inhibition test conducted on a sample of perfluorooctanoic acid, ammonium salt (PFOA), specifically the FC-1015-X product from 3M, noting that the purity was not sufficiently characterized and that the data may not accurately reflect the toxicity of the test substance due to impurities.
|
1996 |
AR226-0524
|
XMq3aKepeLrqn8o494qMMNVg |
9 |
|
The document details a toxicity test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically examining its effects on the aquatic plant species Selenastrum capricornutum using a mixture from the 3M product FC-1015, with findings indicating potential discrepancies in toxicity data due to impurities in the test sample.
|
1996 |
AR226-0526
|
aEr8raKrgXpQYmQjLdvgeKpb |
23 |
|
The document reports on an acute toxicity test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) on Daphnia magna, indicating that the test sample was a mixture with incompletely characterized impurities and was compared to a straight carbon chain version of the substance.
|
1996 |
AR226-0527
|
MGOv20q3kpBwG3R8Z6QpNKxvM |
28 |
|
The document details an acute toxicity test of perfluorooctylsulfonate, a compound produced by 3M, on the fish species Pimephales promelas, using a 96-hour exposure method to assess its effects in a laboratory setting.
|
1996 |
AR226-0534
|
zR46DjzYqL6BR2ax7KnvJXvB |
11 |
|
The document details an acute toxicity test of Perfluorooctylsulfonate (CAS # 251099-16-8) on the aquatic invertebrate Daphnia magna, conducted using a mixture of the test substance and water, with specific monitoring and statistical methods employed to determine toxicity levels.
|
1996 |
AR226-0535
|
2jy0aDDzznEY4rkv1oY4QBvOg |
11 |
|
The document details a Microtox toxicity test conducted on a mixture containing perfluorooctylsulfonate, didecyldimethylammonium salt, produced by 3M, indicating the test sample's composition and preparation methods, but does not provide specific toxicity results.
|
1996 |
AR226-0538
|
YDj9BVapKDJ29KzX3jgRe1R6y |
7 |
|
Unreadable document.
|
1996 |
AR226-1996
|
XOQQkGkjg0z8xazznY0rOQ3ZJ |
2 |
|
The memo discusses recommendations for medical surveillance and exposure control measures for biopersistent fluorochemicals, specifically C-8 (PFOA), at Washington Works and Fayetteville Works, emphasizing the enhancement of engineering controls, ongoing air sampling, and biomonitoring efforts.
|
1996 |
AR226-2023
|
byM8yKVVojwVyVONVB6v966ZD |
3 |
|
The document details a follow-up on C-8 (PFOA) industrial hygiene by presenting the results of job reviews and interviews conducted to understand exposure routes for employees with varying blood levels of C-8 at Playtis Polymers.
|
1996 |
AR226-2024
|
MJD22NBY1DoZrjMbZwpBd5pj |
5 |
|
The document discusses a meeting regarding the biodegradation of C-8 (PFOA) and inquiries about identifying impurities in C-8, with correspondence between DuPont employees John Migliore and David Ellis.
|
1996 |
AR226-1787
|
ppj787wqp4vkM16aLjggMBq4X |
3 |
|
The document discusses the potential for conducting preliminary biodegradability studies on C8 (likely referring to perfluorooctanoic acid, PFOA) and highlights concerns regarding its persistence, while suggesting collaboration with external laboratories for more detailed assessments.
|
1996 |
AR226-1788
|
JJNV0LBDargQBYgD8JnJNEgEO |
2 |
|
This document appears to contain analytical data related to vapor scavenging coefficients and particulate density from testing conducted at the Washington Works site in September 1996, but the specific details are not fully clear due to the formatting.
|
1996 |
AR226-2215
|
91KXXBMR7z74azD5J1NYQbdYD |
1 |
|
This document appears to contain analytical data related to vapor scavenging coefficients for liquid and frozen precipitation, based on testing conducted at the Washington WORT site in September 1996, referencing the EPA ISC Users Guide.
|
1996 |
AR226-2264
|
k9gJKXmXB4RDvbEJNnOKgw9Qb |
1 |
|
The document provides monthly average flow data for the Ohio River at Cincinnati, OH, along with estimates of C8 (PFOA) discharge concentrations and total discharge in 1996.
|
1996 |
AR226-2455
|
1Qx1e4oq43ZM7Qyy23vgpOyLo |
2 |
|
The document reports on a study conducted by Envirogen, Inc. for DuPont to evaluate the ability of nine bacterial strains to aerobically degrade perfluorooctanoate (C8) and ammonium perfluorooctanoate, finding no degradation and recommending further investigation into anaerobic degradation methods and more sensitive analytical techniques.
|
1996 |
AR226-2800
|
gbK1LdkekZZEGLYdE028YEr3Q |
14 |
|
The document discusses pulmonary toxicity following exposure to a reformulated aerosolized leather protector containing fluoroaliphatics, reporting respiratory symptoms in 39 patients and abnormal pulmonary function tests in some, but the mechanism of toxicity remains undetermined.
|
1996 |
AR226-3707
|
Bv7mVEnrZpjDzojDqxd8dwBRX |
3 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal dose (ALD) of the substance H-21333 in rats, completed on January 23, 1996, while noting deviations from Good Laboratory Practice standards that did not affect the study's validity.
|
1996 |
AR226-3036
|
RaNr4V7N9xqLv13JaojGjNDnn |
8 |
|
The document reports on an eye irritation test of the substance H-21460, conducted by E. I. du Pont de Nemours and Company, which found that H-21460 caused moderate eye irritation in rabbits, with symptoms resolving within a few days.
|
1996 |
AR226-3037
|
G5Xqwaan3rV41g1kB7KN4kzex |
11 |
|
The document reports on a skin irritation test of the substance H-21460, conducted by E. I. du Pont de Nemours and Company, which found it to be a mild skin irritant in rabbits, with irritation clearing by 48 hours post-application.
|
1996 |
AR226-3038
|
baqVrMrpGp68pax0bx6D5Jg6o |
10 |
|
The document reports that the approximate lethal dose (ALD) of the substance H-21460, tested by E. I. du Pont de Nemours and Company on male rats, was found to be greater than 11,000 mg/kg, indicating very low toxicity.
|
1996 |
AR226-3039
|
3eKogvwGG3KpZ8R4n4ZY5EaBO |
7 |
|
The document reports a skin irritation test of DuPont's H-21665 on rabbits, revealing that the substance caused mild to moderate erythema and edema, with desquamation observed at 72 hours post-exposure.
|
1996 |
AR226-3041
|
KRgO0EQg5jk3gBvLy4vMKb8p2 |
9 |
|
The document reports on a skin irritation test conducted by E. I. du Pont de Nemours and Company on the substance H-21987, which was found to be a mild skin irritant in rabbits, with varying degrees of erythema observed.
|
1996 |
AR226-3042
|
YGVQMDNvwa9MpK64LBMxkLrE0 |
10 |
|
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company, which found that the substance H-21987 caused moderate eye irritation in rabbits, with symptoms resolving within one to three days depending on whether the eye was washed after treatment.
|
1996 |
AR226-3043
|
nkgk8zbOZw5xXXepx6N7V40Rm |
12 |
|
The document reports on a skin irritation test conducted by E. I. du Pont de Nemours and Company on the substance H-21951, which was found to be a mild skin irritant in rabbits, showing slight erythema at 1 and 24 hours post-exposure but clearing by 72 hours.
|
1996 |
AR226-3044
|
JvdRR1xv1kRrogdqKGLwprQr2 |
10 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Company evaluating the acute eye irritation potential of the substance H-219S3 in rabbits, which resulted in moderate conjunctival redness and iritis, but no long-term toxicity, with both treated eyes returning to normal by day three post-treatment.
|
1996 |
AR226-3045
|
50DNN8o6Dm0xqMXvXvvZLVNa4 |
12 |
|
The document reports on a skin irritation test of the substance H-21953, conducted by E. I. du Pont de Nemours and Company, which showed that the substance caused slight or mild erythema in rabbits at 1 and 24 hours post-exposure.
|
1996 |
AR226-3046
|
DZ1d2g2zGMJ3y9rmMm1QgYLn |
10 |
|
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company on the substance H-21951, which resulted in moderate conjunctival redness and slight chemosis in rabbits after instillation.
|
1996 |
AR226-3047
|
YDKnQL88yX52rp6qq5kjqr3R8 |
12 |
|
The document reports on a study conducted by DuPont to determine the approximate lethal dose (ALD) of the substance H-21951 in rats, finding that no deaths occurred at doses greater than 11,000 mg/kg.
|
1996 |
AR226-3048
|
0gamG1vdZDRXXrb964M39QgGd |
8 |
|
The document reports on a study conducted by DuPont assessing the approximate lethal dose (ALD) of the substance H-21953 in male rats, finding it to be greater than 11,000 mg/kg, indicating very low toxicity.
|
1996 |
AR226-3049
|
2RQxpo06qvjQzjkYg55QQOy8p |
8 |
|
The document reports on a skin irritation test conducted by E. I. du Pont de Nemours and Company on the substance H-21946, which showed slight or mild erythema but no edema in rabbits after a 4-hour exposure.
|
1996 |
AR226-3050
|
RxDj8j9q5y7xZemXRrbBZyQV |
10 |
|
The document reports on a Local Lymph Node Assay conducted by DuPont using the test substance H21951, which showed no sensitization effects in female CBA/JHsd mice at various concentrations, while a positive control with hexylcinnamaldehyde demonstrated a sensitization response.
|
1996 |
AR226-3052
|
2Rd2ybpy640oB61MzJw3KEdBL |
1 |
|
The document reports on an eye irritation test conducted by DuPont on the substance H-21946, which resulted in mild to moderate conjunctival redness and slight chemosis in rabbits, indicating its potential irritative effects.
|
1996 |
AR226-3051
|
jKkKDqYvY8eLZdnO05d7vO3Q |
12 |
|
The document reports on a Local Lymph Node Assay (LLNA) conducted by DuPont to evaluate the sensitization potential of a test substance (H21953) in female mice, concluding that H21953 was not a sensitizer while hexylcinnamaldehyde (HCA) produced a positive sensitization response.
|
1996 |
AR226-3053
|
XxoJyDvwQMy79Ed7dBXN8E6w |
1 |
|
The document reports on a Local Lymph Node Assay (LLNA) conducted by DuPont to evaluate the sensitization potential of the substance H22051 in female CBA/JHsd mice, concluding that H22051 is not a sensitizer, as all stimulation indexes were below 3.0 and no dose response was observed.
|
1996 |
AR226-3054
|
qkpzjopO258BV4Oa6Gx1OKyBR |
1 |
|
The document reports that the substance H-21987, tested by E. I. du Pont de Nemours and Company, showed an approximate lethal dose greater than 11,000 mg/kg in male rats, indicating very low toxicity when administered as a single oral dose.
|
1996 |
AR226-3056
|
QJNJyDeRad32qmOOYZyOwErY5 |
8 |
|
The document reports on a 100-person human patch test conducted by ConTox Limited for E. I. du Pont de Nemours and Company, which found that the substance H-22056, associated with PFOA, did not cause skin irritation or sensitization in participants.
|
1996 |
AR226-3057
|
xzROmbk2zxjrMVqaM94D3LwQy |
19 |