|
The document discusses water sample tests conducted by DuPont on September 18, 2000, revealing the presence of PFOA (C-8) in the river and traces in Outfall No. 5, while one sample from Outfall No. 5 showed only water.
|
2000 |
AR226-2479
|
859dMN8G7vkrLe7xDnvvOD8Y5 |
1 |
|
The document discusses extraction study results indicating that C-8 (likely referring to PFOA) levels in water are approximately 1 ppb, which is below community guideline levels, suggesting no concerns regarding rain runoff from the storage area of supermate briquettes.
|
2000 |
AR226-2481
|
ppBvGqZLKw9VYwKrw1LYQE52D |
1 |
|
The document contains analytical results for water samples taken from three wells and a main water line by DuPont, indicating the presence of PFOA with a reported concentration of 0.535 ug/l, which is outside the quality control limits for certain recovery tests.
|
2000 |
AR226-2480
|
2j6GBQgLEVME9YGyyDdoy4K0g |
8 |
|
DuPont is preparing to respond to a significant data request from the EPA regarding PFOA and PFOS, prompted by concerns over reproductive effects associated with PFOS, and the request will require extensive toxicity studies, emissions data, and human exposure information.
|
2000 |
AR226-2553
|
gaGk4MnXgqoLnX1Z9XvRN91g9 |
3 |
|
The document contains meeting notes from a discussion among DuPont employees regarding their response to the EPA's inquiries about PFOS and PFOA, indicating that DuPont does not manufacture PFOA or PFOS and outlining action items for providing relevant data to the EPA.
|
2000 |
AR226-2554
|
6ROoq1YJeLRRdE4ayz8JZboaR |
3 |
|
DuPont is coordinating the collection of extensive data on Perfluorooctanoate (PFOA) to respond to an EPA request, which includes toxicity, environmental fate, human exposure, and emission data, with submission deadlines set for May 28th and June 23rd.
|
2000 |
AR226-2555
|
BvM4rv1nQ8ynoyjjgeK3mBE4 |
1 |
|
This document is a letter from DuPont to the EPA summarizing the use and exposure of ammonium perfluorooctanoate (APFO) in their fluoropolymer manufacturing processes, emphasizing that DuPont does not manufacture APFO, that most of it is removed from products before sale, and that worker exposure levels are significantly below the ACGIH threshold limit value.
|
2000 |
AR226-2556
|
712gqmJ04rKjv00aLVeom5ya8 |
11 |
|
The memo discusses a meeting regarding DuPont's groundwater monitoring and contamination investigation at the Washington Works facility, highlighting concerns about the lack of monitoring wells in the manufacturing area to assess the impacts of past PFOA-related manufacturing processes.
|
2000 |
AR226-2567
|
jyMxkey337KJ79J8o9mRQOyr2 |
2 |
|
This document appears to be a figure or map related to the monitoring program wells at the Oakdale Disposal Site in Minnesota, indicating various well types and sampling locations.
|
2000 |
AR226-3644
|
mbkya9EEO5yg51qbb7o6nO84d |
1 |
|
3M Company is requesting the U.S. EPA to redesignate thirty studies related to health and environmental effects of various fluorochemicals, including PFOS, to the TSCA Section 8(e) docket for further consideration.
|
2000 |
AR226-3654
|
gb3RoGYqNYdbQwODBB2vrzrJL |
4 |
|
The document is a confidential study report conducted by Elf Atochem S.A. on the acute eye irritation effects of a test substance in rabbits, completed on January 27, 2000, at the Centre International de Toxicologie.
|
2000 |
AR226-3144
|
OJk6R6D7jZED2ZmDpJxrMneVQ |
21 |
|
This is a DuPont study report (Project ID DuPont-3823) on a Local Lymph Node Assay (LLNA) completed on April 28, 2000, authored by Gregory S. Ladies, PhD.
|
2000 |
AR226-3147
|
zzzgLx3oJKy0Nk9aZvrBexZY7 |
13 |
|
The document reports on an in vitro mammalian chromosome aberration test conducted on a substance identified as H-24335, for E.I. du Pont de Nemours and Company, using Chinese Hamster Ovary (CHO) cells to evaluate its potential genotoxic effects.
|
2000 |
AR226-3148
|
5kzgQaq7jr3dy56oE09zeqgVJ |
39 |
|
This document outlines the development and evaluation of an LC-API/MS/MS analytical method for the analysis of PFOC and PFOs in liquid surfactants, with a focus on optimizing the method specifically for PFOC while achieving good accuracy and linearity for PFOs.
|
2000 |
AR226-3335
|
KRkQ2O7X8mRXD13dNnXVY6zEx |
6 |
|
The document discusses perfluoroalkylated substances (PFAS), particularly focusing on PFOA and PFOS, their sources, environmental presence, and toxicity, highlighting their detection in humans and biota globally, with suggestions for future research.
|
2000 |
AR226-3345
|
LM9RzozLw6rRn2jvo2jLQYk7 |
1 |
|
The document reports on an in vitro mammalian chromosome aberration test conducted on Chinese Hamster Ovary (CHO) cells to evaluate the effects of a substance associated with DuPont, specifically under study number DuPont-3871.
|
2000 |
AR226-3149
|
rpG61Yxz3pqx25bLRd73E5qeG |
40 |
|
This is a DuPont study report (Project ID DuPont-4199) detailing a Local Lymph Node Assay (LLNA) conducted by E. I. du Pont de Nemours and Company, with a completion date of May 4, 2000.
|
2000 |
AR226-3150
|
NeZvpdMM7gB1LbVMOGEYB5Kyw |
13 |
|
The document is a biopersistence screening study report conducted by E.I. du Pont de Nemours and Company on an unspecified test substance, likely related to PFOA or PFOS, involving a 10-dose oral gavage study in rats, completed on May 19, 2000.
|
2000 |
AR226-3152
|
OJ8b47vkvXnQMj9rBVXxoVVz1 |
82 |
|
The document discusses blood test results for C-8 (PFOA) in pensioners from DuPont, indicating a half-life estimate of about four years based on comparisons of blood levels from 1995 and 2000 after retirement.
|
2000 |
AR226-3761
|
X7V3Jyn2Vx1Ro9zmZnaoZ3bp4 |
1 |
|
The document is a biopersistence screening study report conducted by DuPont on PFOA in rats, completed on July 27, 2000, and certified by senior research scientists.
|
2000 |
AR226-3155
|
LG7r9EX9MK729NwrYYZ3jzmX |
80 |
|
The document is a biopersistence screening study report conducted by E.I. du Pont de Nemours and Company on an unspecified test substance, likely related to PFOA or PFOS, using a 10-dose oral gavage method in rats, completed on August 3, 2000.
|
2000 |
AR226-3156
|
oDp63b0bYjV23r476kG3Emee7 |
81 |
|
This document is a confidential skin sensitization study report conducted by Elf Atochem SA on a test substance, likely related to perfluorinated compounds, using guinea pigs to assess allergenicity through the maximization method.
|
2000 |
AR226-3158
|
3QdnjD14kEQO9kVmxXbapyvgD |
32 |
|
The document is a biopersistence screening study report conducted by DuPont on an unspecified test substance involving 10-dose oral gavage in rats, completed on August 3, 2000.
|
2000 |
AR226-3157
|
GQDowrGoqvOaYZ9DBGQydxY |
82 |
|
The document is a study report titled "H-23926: Biopersistence Screening 10-Dose Oral Gavage Study in Rats" conducted by DuPont, evaluating the biopersistence of a test substance related to perfluorinated compounds.
|
2000 |
AR226-3159
|
Qk5j0nqn9kvBbYmpYxkNx2wr4 |
81 |
|
The document is a study report titled "H-23925: Biopersistence Screening 10-Dose Oral Gavage Study in Rats" conducted by DuPont, focusing on the biopersistence of a perfluorinated compound, with the study completed on August 29, 2000.
|
2000 |
AR226-3160
|
XQYnxdgxD091wgkVLNExBwqK |
109 |
|
The document is a study report from DuPont titled "H-24042: Biopersistence Screening 10-Dose Oral Gavage Study in Rats," which evaluates the biopersistence of a perfluorinated compound, although the specific substance is not mentioned in the provided text.
|
2000 |
AR226-3161
|
eYo1dZJ7g6bxzbVKRODv3wgE |
83 |
|
The document discusses the ecotoxicity profile of 1H,1H,2H,2H-Perfluorodecanol (CAS No. 678-33-7), highlighting its role as a specialty intermediate in the production of Tetomer-based Polymeric Products (TBPPs) used for textile and carpet coatings, and outlines the challenges and testing strategies developed to assess its environmental
|
2000 |
AR226-3358
|
ByD5pGqdgBgVBzOd4LnrM2V4j |
1 |
|
The document evaluates the potential environmental exposure, persistence, and long-range transport potential of perfluorinated 8-2 Telomer B Alcohol (8-2 TBA) using multimedia models in the context of its industrial applications in Germany and the EU.
|
2000 |
AR226-3359
|
6wgw9Rqd8x4qnmwdpNo34aeaE |
1 |
|
The document reports on a 96-hour acute toxicity screening test of the substance H-24159, conducted by E.I. du Pont de Nemours and Company, which assessed its effects on the fathead minnow (Pimephales promelas) and found that the substance was stable during the study.
|
2000 |
AR226-3163
|
O11bq8JJ2kVRwbKvky0Zy0jGw |
5 |
|
This document is a biopersistence screening study report conducted by DuPont on the oral gavage of a substance, likely related to PFOA or PFOS, in rats, completed on August 29, 2000.
|
2000 |
AR226-3162
|
E7L9Ya4Q9J0R3g3qd7b4NERR |
93 |
|
The document is a biopersistence screening study report conducted by DuPont on the effects of a 10-dose oral gavage of a trade secret substance in rats, completed on September 1, 2000.
|
2000 |
AR226-3164
|
O3Zye9j14KQV26mm2pNXYyxrL |
93 |
|
The document reports on a study conducted by E.I. du Pont de Nemours and Company that assessed the acute toxicity of the substance H-24516 (a perfluorinated compound) to fathead minnows (Pimephales promelas), finding 100% mortality at the highest concentration of 1000 mg/L after 96 hours.
|
2000 |
AR226-3167
|
oa7qVXeMzXaDbv67ZDp6V9x3 |
5 |
|
This document is a biopersistence screening study report conducted by DuPont on the effects of a 10-dose oral gavage of a perfluorinated compound in rats, completed on September 5, 2000.
|
2000 |
AR226-3165
|
82q8ZQ0RDVYKowxemG2VnqVey |
93 |
|
This document is a study report from DuPont detailing a biopersistence screening of a test substance conducted through a 10-dose oral gavage study in rats, completed on September 5, 2000.
|
2000 |
AR226-3166
|
baowg539rg510nxwezmrZx6kZ |
93 |
|
The document reports on a study conducted by DuPont assessing the acute toxicity of a substance identified as H-24615 to the fathead minnow (Pimephales promelas), revealing 100% mortality at a concentration of 1000 mg/L after 96 hours of exposure.
|
2000 |
AR226-3169
|
rBp61xZ1rERr3kD4pkvanRY0J |
5 |
|
The document reports a study by DuPont on the effects of the substance H-24616 on the growth and growth rate of the green alga Selenastrum capricornutum, finding an EC50 of 30 mg/L and a NOEC of 100 mg/L, indicating medium concern under TSCA due to its acute toxicity to aquatic organisms.
|
2000 |
AR226-3170
|
Dv9011Ky6aj44K2aOkX8Yg42N |
13 |
|
This document details a skin sensitization study conducted by Elf Atochem SA on a test substance using guinea pigs, following the maximization method of Magnusson and Kligman, with the study completed on December 14, 2000.
|
2000 |
AR226-3172
|
2jBzZJ5LJNoDp0ZaB401geaKr |
32 |
|
The document is a study report conducted by BioReliance for E. I. du Pont de Nemours and Company, detailing a reverse mutation study related to perfluorinated compounds, specifically conducted in compliance with EPA GLP standards.
|
2000 |
AR226-3171
|
jgEa7Z222Jea0jwVrQrrNkopN |
65 |
|
The document details a two-week inhalation toxicity study of a test substance conducted by E.I. du Pont de Nemours and Company on male rats, which complied with U.S. EPA TSCA Good Laboratory Practice Standards, despite some minor deviations that did not affect the study's validity.
|
2000 |
AR226-3168
|
3ejBre0x2zzX2V3Lg8mMLXEzy |
181 |
|
This is a DuPont analytical report (Supplement No. 1 for Study H-24001) detailing a biopersistence screening 10-dose oral gavage study in rats, completed on December 12, 2001.
|
2000 |
AR226-3203
|
RpVDLjoEvyz6Bbb55mZ0yaKJV |
40 |
|
The document is a supplement to a biopersistence screening study conducted by DuPont on the oral gavage of rats, focusing on the evaluation of liver weights as part of the assessment of PFOA.
|
2000 |
AR226-3204
|
5km9oLKjOwQyjN3V2EVr0dqmR |
40 |
|
The document is a supplement report from DuPont detailing a biopersistence screening study of PFOA conducted through a 10-dose oral gavage in rats, completed on December 12, 2001.
|
2000 |
AR226-3205
|
MGrGxyLjO9axbaQeGrJkQZm9L |
40 |
|
The document is a supplement report for a biopersistence screening study on DuPont's test substance (likely PFOA or a related perfluorinated compound) conducted on rats, detailing the study's methodology, results, and conclusions.
|
2000 |
AR226-3209
|
V6EgG6vG7J5JeJJdzeaRjDxw |
40 |
|
This is a DuPont analytical report (Supplement No. 1 for Study H-23925) detailing a biopersistence screening 10-dose oral gavage study in rats, completed by the Haskell Laboratory for Health and Environmental Sciences.
|
2000 |
AR226-3210
|
jYjbeg0Xar0rzganYyK1Y9xZ |
40 |
|
This document is a supplement to a biopersistence screening study on PFOA conducted by DuPont, detailing the methodology and findings from a 10-dose oral gavage study in rats, completed in 2001.
|
2000 |
AR226-3211
|
XO1OvBOYOkpjvoov2ZkXkzXby |
40 |
|
The document is a certification report for a biopersistence screening study of an unspecified perfluorinated compound conducted by DuPont, detailing the methodology and findings from a 10-dose oral gavage study in rats.
|
2000 |
AR226-3216
|
0LaGD59MMzJzXME6m5vaqq3NV |
40 |
|
This is a DuPont analytical report (Supplement No. 1 for Study H-24159) detailing a biopersistence screening 10-dose oral gavage study in rats, completed on January 11, 2002.
|
2000 |
AR226-3217
|
oDVK41DX3kJ6JmX5bBe7248JE |
40 |
|
Pace Analytical Services, Inc. conducted resampling for the Port St. Lucie Multi-City Study under contract with 3M to confirm baseline data on fluorochemicals, specifically targeting PFOS, PFOSA, POAA, PFHS, and TFA, originally collected in July 1999.
|
2000 |
AR226-0680
|
pp7XnQLn55nVZQpvmgxg9ao8B |
13 |
|
This is a final report prepared by Battelle Memorial Institute for 3M Specialty Materials, detailing life-cycle waste stream estimates for sulfonated perfluorochemicals in the U.S. from 1997.
|
2000 |
AR226-0681
|
Rj5e8XqnD4bxmqpgRymwOK297 |
11 |
|
3M is providing the EPA with information on perfluorooctane sulfonates (PFOS) mixtures, specifically noting that potassium perfluorooctane sulfonate is deliberately added to their aqueous fire fighting foam products at low levels, and that they are submitting health and environmental laboratory studies related to these products.
|
2000 |
AR226-0682
|
v68p4rbjnO4qLLJ262Bbg3r0Z |
41 |
|
The document details an acute toxicity test conducted on the aquatic invertebrate Corophium volutator using a mixture containing 1.34% perfluorooctanesulfonate (PFOS) as part of the test substance FC-203, highlighting the methodology and conditions of the experiment.
|
2000 |
AR226-0730
|
bBQODEDXayXEY0JRZLn35XGLg |
34 |
|
The document reports on an acute toxicity test of a PFOS-containing mixture (FC-602) conducted on the aquatic invertebrate Corophium volutator, using standard methods to evaluate its impact over a 10-day exposure period.
|
2000 |
AR226-0847
|
vBN09BMJbvDeE5d4dDVVMeNMZ |
35 |
|
The document details an acute toxicity test of a mixture containing 1.30% perfluorooctanesulfonate (PFOS) on the aquatic invertebrate Corophium volutator, conducted using ASTM E1367-90 methodology, with findings potentially affected by impurities in the test sample.
|
2000 |
AR226-0861
|
wgmJ9gevyGg4aKZ1ddd97ZKjo |
34 |
|
3M submitted a revised "Use and Exposure Information Profile" for perfluorooctane sulfonic acid (PFOS) to the EPA, providing additional details on their environmental and industrial hygiene management of the substance at their manufacturing facilities.
|
2000 |
AR226-0927
|
DDb650ZqgGEo3Q9g3eQYbkgGn |
1 |
|
The document is a letter from the EPA to 3M Company regarding the provision of scanned files from the TSCA Administrative Record on PFOS and related compounds, including submissions from 3M and DuPont, and instructions for future submissions.
|
2000 |
AR226-0929
|
pBrpazkNJ6Lq6mx4zjz6Xjb7D |
1 |
|
The document is a letter from 3M to the EPA detailing the CAS numbers and names of perfluorooctanyl chemistry products that 3M will phase out, including various perfluorinated compounds.
|
2000 |
AR226-0931
|
JNVxg31jgONJDB0Q4MwV2wBgB |
5 |
|
Dainippon Ink & Chemicals, Inc. is confirming a meeting with the U.S. EPA on September 15th regarding PFOA/PFOS, with representatives attending due to the absence of their president.
|
2000 |
AR226-0933
|
2462k2gz0dXebDeGvYXj59E5 |
1 |
|
This letter from 3M formalizes a response to the EPA regarding the classification of chemical names and phase-out dates for perfluorinated compounds, specifically stating that the information is not considered confidential business information (CBI) and confirming phase-out dates for industrial surfactants and fire fighting foams.
|
2000 |
AR226-0932
|
7MEeqjb70b04eGjn1My4m6EZ6 |
3 |
|
The document provides a voluntary use and exposure information profile for perfluorooctane sulfonates (PFOS) and various salt forms produced by 3M Company, detailing their chemical identification, manufacturing processes, and distribution estimates.
|
2000 |
AR226-0928
|
emRpb1wG5Mn1oBjz7Xn0rKvQg |
34 |
|
Dainippon Ink & Chemicals Inc. is requesting a meeting with the U.S. EPA on September 15, 2000, to discuss the issue of PFOS, acknowledging the EPA's support for 3M's decisions regarding the substance.
|
2000 |
AR226-0934
|
gb2krZbp85yBGdjRZnmeVzo9 |
2 |
|
The document is a communication from Deltoppon Ink & Chemicals Inc. regarding a meeting with the U.S. EPA on September 15, 2000, to discuss regulatory aspects of PFOA and other perfluorinated compounds.
|
2000 |
AR226-0935
|
bqB7z7Ba1KE5QLdKJ8roXmN0 |
1 |
|
The document is a letter from the EPA's Office of Prevention, Pesticides and Toxic Substances to Dainippon Ink & Chemicals, Inc., confirming a meeting to discuss technical uses of PFOS and clarifying that the discussion will not involve negotiations.
|
2000 |
AR226-0936
|
E393L5znmRQyJv51oyRex88j |
1 |
|
Kidde Fire Fighting informs the EPA that their foam concentrates, which do not contain PFOS due to the TFE process, can meet market demand and expresses confidence in the industry's ability to avoid product shortages amid discussions of extending the 3M foam concentrate phase-out plan.
|
2000 |
AR226-0940
|
r633qVkG6MJg0nmO9d0pXyXK7 |
1 |
|
IKEA's Quality Department inquired about the environmental and health effects of DuPont's Teflon-based finish in comparison to PFOS, as they are phasing out products treated with 3M's Scotchgard due to the EPA's efforts to address PFOS and related chemicals.
|
2000 |
AR226-0941
|
rBDj701D621QaGjj04RLYd22e |
1 |
|
The Boeing Company is informing the EPA that it has been using FC-98, a fluorinated compound critical for hydraulic fluid performance in aircraft, and is concerned about its impending phase-out by 3M, the sole domestic manufacturer, as there are currently no alternatives available.
|
2000 |
AR226-0943
|
g2pmvBQwQgV80YY8MV4K1Ze29 |
5 |
|
The document is a note summarizing a meeting held on September 15, 2000, to discuss alternatives to PFOS for carpet treatment, attended by representatives from Shaw Industries and the EPA.
|
2000 |
AR226-0945
|
7M2rodL8axOrB4QZ47w4rjw16 |
1 |
|
The document is a revised PFOS hazard assessment from October 23, 2000, by Karen Lannon, which includes minor textual corrections from the original version but does not alter the conclusions.
|
2000 |
AR226-0946
|
933vpZmDZVdYJzrxBb3one5wR |
29 |
|
The document is a status report on the Telomer Research Program presented to the U.S. EPA, detailing the program's organization, guiding principles, and management structure for research on perfluorinated compounds by member companies including DuPont and Daikin.
|
2000 |
AR226-0947
|
ZnqYnG0BLEbVXaG30kpBxGDK0 |
153 |
|
DuPont is seeking expert assistance to defend against a lawsuit from a farmer in West Virginia alleging health and environmental impacts related to PFOA from a non-hazardous landfill, despite their assessment indicating negligible risks to the farmer's cattle.
|
2000 |
AR226-1676
|
50bvY96NmMJMZva24yj9b9ww8 |
1 |
|
This document reports on a pharmacokinetic study of T-6246 (FC-95) conducted by 3M, revealing that perfluorooctanesulfonate anion has a half-life of one month or greater in rabbit serum and liver, with detectable fluorine levels following a 0.12 mg/kg dose but not after a 0.012 mg/kg dose.
|
2000 |
AR226-0948
|
n995ErjNDB1LzKjamB3jGbQ11 |
281 |
|
This is a cover page from Pace Analytical Services, Inc. for the 3M Multi-city Food Study, prepared under contract with 3M for project number E00-2789.
|
2000 |
AR226-1698
|
Xw1z0wxVvJ2BxokoNb49x6qK |
1 |
|
This document is a correspondence from Larry R. Zobel of 3M to Dr. Oscar Hernandez at the US EPA, providing additional documents related to studies on PFOS and PFOA that were inadvertently omitted from a previous package.
|
2000 |
AR226-0612
|
r4z95eqJb90Vb0y2KY60vQoe |
1 |
|
This document is a correspondence from 3M's Corporate Toxicology department to the EPA, providing serum measurements for perfluorooctanesulfonate (PFOS) from two pharmacokinetic studies conducted on rats.
|
2000 |
AR226-0612
|
MobeQG5MvBRjBnYaOKGqa0o8z |
1 |
|
3M is providing supplemental information to the EPA regarding perfluorooctane sulfonates (PFOS), including executive summaries and a summary of a 26-week toxicity study in cynomolgus monkeys, to complete their previous submission from May 4, 2000.
|
2000 |
AR226-0612
|
k9KO1Lj2oXaD56o3J9BxN3nJD |
1 |
|
This document is a correspondence from 3M's Corporate Toxicology department confirming the submission of a non-confidential version of a toxicological study on perfluorooctane sulfonates to the EPA, following a request for information.
|
2000 |
AR226-0612
|
a4oGr4de671RONO0ayOmbDn0y |
1 |
|
This document reports on a 26-week toxicity study of potassium perfluorooctanesulfonate (PFOS) in Cynomolgus monkeys, revealing severe health effects at the highest dose of 0.75 mg/kg/day, including illness and changes in body weight, liver function, and hormone levels, while lower doses showed no significant effects.
|
2000 |
AR226-0612
|
mBG7aEbg46vornRG25p3Da9Ed |
1 |