|
The document reports that a static acute toxicity test conducted by 3M Company on bluegill sunfish (Lepomis macrochirus) using perfluorooctanoic acid, ammonium salt (PFOA ammonium salt) found the 96-hour LC50 to be greater than 420 mg/L, indicating low toxicity at the highest concentration tested.
|
1978 |
AR226-0499
|
bBVpKNzr81mq6JVMzn5d6aL71 |
3 |
|
The document reports on an acute toxicity test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) conducted on bluegill sunfish, revealing a 96-hour LC50 value of 569 mg/L.
|
1978 |
AR226-0500
|
5kwGDrzBgvVKVwOZ89R6E5wq8 |
3 |
|
The document reports on a study conducted by E G & G, Bionomics Aquatic Toxicology Laboratory for 3M Company, which found that continuous aqueous exposure to PFOA (referred to as 78.03) did not affect the hatchability of fathead minnow eggs or the survival, growth, and weight of fry over a 30-day period post-hatch.
|
1978 |
AR226-0502
|
x5ZDkepXgLwDrwky7Yk9omdVy |
19 |
|
The document reports on histopathological examinations of fathead minnows (Pimephales promelas) exposed to the substance 78.03 for 30 days, assessing potential sub-lethal effects following an earlier egg and fry test conducted for 3M Company.
|
1978 |
AR226-0503
|
oD2jvbakwBVdLkaOve3Mwaed3 |
8 |
|
The document reports the results of an acute toxicity test on Perfluorooctanesulfonate (PFOS) conducted on bluegill sunfish, revealing a 96-hour LC50 value of 68 mg/L.
|
1978 |
AR226-1755
|
rBeYze0m9owJQQ0nEdkqeyOmq |
2 |
|
This document summarizes studies conducted by 3M Company on perfluorooctanesulfonate (PFOS) from 1977 to 1979, detailing various tests on water solubility, biodegradation, soil sorption, and acute toxicity to aquatic species, while noting deficiencies in data quality and substance characterization.
|
1977 |
AR226-0123
|
DMpwEJZO21G9DoLzwJwD3Y7L5 |
16 |
|
The document reports the results of mutagenicity testing using the Ames spot test on various chemical samples, indicating that none of the samples tested, including those marked with an asterisk, showed mutagenic activity.
|
1977 |
AR226-0129
|
dnRx23Jb5zOkm02Oz7Xn8nLqQ |
1 |
|
The document summarizes a study conducted for the German Government Agency for Military Technology and Procurement on the environmental properties of fire extinguishing foam compounds, specifically analyzing a mixture containing 1.8% PFOS from 3M's FC-200, with various toxicity and chemical assessments performed in 1977.
|
1977 |
AR226-0688
|
MoKE8Y3v5VNVXm6jL070kBq8a |
28 |
|
The document summarizes a study conducted for the German Government Agency for Military Technology and Procurement on the environmental properties of fire extinguishing foam containing 0.67% PFOS from 3M's FC-206, including various toxicity and chemical analyses.
|
1977 |
AR226-0793
|
99VevBmNGewggrBvOba0o54Re |
28 |
|
This document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on Daphnia magna, indicating that the test sample FC-600 consists of 1.0% PFOS and various other components, with results derived from a 48-hour exposure period.
|
1977 |
AR226-0828
|
Jz7qMgk3apXzdLOYEY4dEpXr |
5 |
|
This document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) in Daphnia magna, using a sample of FC-600 treated in a SCAS reactor, with findings indicating the need for caution due to the presence of impurities and incomplete characterization of the test substance.
|
1977 |
AR226-0829
|
omN592pQEprg1rzQJ48EJj728 |
4 |
|
The document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) in Daphnia magna, indicating that the test sample FC-600, treated in a SCAS reactor, was evaluated for its toxic effects, although the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization of impurities.
|
1977 |
AR226-0830
|
bBDDK7ebKkL6QqYJedwp81x5y |
4 |
|
This document summarizes a study conducted for the German Government Agency for Military Technology and Procurement, evaluating the environmental properties and toxicity of a fire extinguishing foam containing 0.67% PFOS (perfluorooctanesulfonate) from 3M's FC-3017 mixture, alongside other chemical components.
|
1977 |
AR226-0896
|
8OzzYjy5VvkGLg4RvYXybmx0d |
28 |
|
The document details studies conducted by 3M on the soil adsorption properties of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol), indicating that it is likely to sorb to soil, although the studies lack detailed methodologies and characterization of the test substance's purity.
|
1977 |
AR226-0349
|
YQ2YD9vj43VE6bzkJXQDnrLN |
7 |
|
The document details a bioconcentration test of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol) conducted on bluegill and channel catfish to determine its aquatic bioconcentration factor, utilizing a static exposure method over specified periods without GLP compliance.
|
1977 |
AR226-0350
|
2qrnqz98X47pbL9pX7YqEdK2a |
17 |
|
The document reports on a hydrolysis test conducted by 3M Company, which found that N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol) partially degrades to perfluorooctane sulfonate (PFOS) in a 20% alcoholic potassium hydroxide solution, achieving a 92% degradation after 24 hours at
|
1977 |
AR226-0364
|
x92DL9KQXzpDo7n5Q6jJEVY0 |
4 |
|
The document reports on biodegradation testing of Perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) conducted by 3M Company, indicating that no reliable conclusions could be drawn due to insufficient data and dissolved oxygen depletion.
|
1977 |
AR226-0399
|
82nGLpaemY9qqwb2Om9vkVJVB |
4 |
|
This document reports on an acute toxicity test of perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) conducted on the fish species Pimephales promelas, revealing a 96-hour LC50 value of 100 mg/L.
|
1977 |
AR226-0402
|
QkrEG6EvDBMyYd8GxbBeMnGe7 |
6 |
|
This document reports on a 28-day oral toxicity study conducted by Bio-Test Laboratories for 3M Company on the substance FC-143, revealing that all rats fed 10,000 ppm or more died within the first week, while significant reductions in body weight gains were observed at doses of 1,000 ppm and higher.
|
1977 |
AR226-0445
|
zZ6wzn8ggZ8ZoQxBkzq4q7g3 |
20 |
|
The document is a summary of a biodegradation study on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), conducted by 3M Company in 1977, which concluded that no reliable conclusions could be derived due to the lack of original study procedures and raw data.
|
1977 |
AR226-0487
|
e7kEe6dRJxJ54M83Q33O7gjXm |
3 |
|
This document reports on biodegradation testing of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the results do not accurately reflect the degradation potential of the fluorochemical component due to incomplete characterization of impurities and lack of methodological details.
|
1976 |
AR226-0777
|
X7vdLOLGqGVO4vRygDjNag1gd |
4 |
|
This document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on fathead minnows (Pimephales promelas), indicating that the test sample was composed of 0.67% PFOS among other components, with the study conducted in 1976 under non-GLP conditions.
|
1976 |
AR226-0789
|
YDYGD8QQK4mr81wpoxw5L89vV |
3 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating that the test sample was a mixture with 0.67% PFOS and various other components, but the data may not accurately reflect the toxicity of the fluorochemical due to incomplete characterization of impurities.
|
1976 |
AR226-0790
|
EqYw1QDk4yaVwBYk6mv7VwQeg |
5 |
|
The document summarizes acute toxicity studies on a mixture containing 0.96% PFOS (perfluorooctanesulfonate) from 3M's FC-3031, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1976 |
AR226-0897
|
9JQeL30jv2O5373Ea8yqjOewV |
6 |
|
The document details a soil adsorption study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), conducted in 1978, using specific methodologies to analyze its interaction with Brill sandy loam soil.
|
1976 |
AR226-0348
|
e17NenGqL5qKQDRgnQLaryXxy |
14 |
|
The document details biodegradation studies of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), indicating that initial tests showed minimal oxygen uptake and no detectable degradation products, likely due to the substance's coagulation preventing enzymatic attack.
|
1976 |
AR226-0356
|
VNBEpKvDy0vNX8Gy9Gk3rZYK |
67 |
|
The document reports on a biodegradation study of N-methylperfluorooctane sulfonamidoethanol (N-MeFOSE alcohol), indicating that it is unlikely to degrade in non-acclimated aerobic biological treatment systems due to insufficient biochemical oxygen demand (BOD) results, despite high chemical oxygen demand (COD) values.
|
1976 |
AR226-0368
|
Rab4wRgN9EqLGykwZmkRrXRXn |
12 |
|
The document details a soil adsorption study of N-methylperfluorooctane sulfonamidoethanol (N-MeFOSE Alcohol), conducted in 1979, which involved preparing various concentrations of the substance and analyzing its adsorption and desorption properties in Brill sandy loam soil.
|
1976 |
AR226-0370
|
MG9z0r8eLeEJXEZZ3wakMpyj9 |
17 |
|
The document reports on a biodegradation study of perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA, FC-128), indicating that approximately 70% of the theoretical maximum oxygen uptake occurred within a 7-hour period, suggesting potential biodegradability under aerobic conditions.
|
1976 |
AR226-0398
|
wbg95w2pY6MzL3RbnKnR1KyJ |
39 |
|
The document reports on an acute oral toxicity study conducted by Biosearch, Inc. for 3M Company, which found that the LD50 of the tested material (3M Company - T-1565) in male and female albino rats is less than 1,000 mg/kg, with observed signs of toxicity including gastric mucosa erosion and writhing.
|
1976 |
AR226-0425
|
O1r1YbR0wyYV8vnNe8gq1MEKv |
2 |
|
The document reports on a primary eye irritation study conducted by 3M Company on a test material (T-1585) to evaluate its potential irritative effects when instilled into the eyes of rabbits, with results indicating the degree of irritation observed.
|
1976 |
AR226-0426
|
0qNNyXvERGGj0Y65R7ddo8eOR |
3 |
|
The document reports on reverse mutation studies conducted by 3M Company on a sample identified as T-1485, evaluating its mutagenic activity using five Salmonella strains and one Saccharomyces strain.
|
1976 |
AR226-0989
|
Ed2KvJRQeGDVeOODyqRN3gbdR |
9 |
|
The document details an acute toxicity test of Perfluorooctanesulfonate (PFOS DEA salt) on the fish species Lepomis macrochirus, conducted under EPA guidelines, with a focus on the effects of a 96-hour exposure to a test mixture containing approximately 25% PFOS.
|
1975 |
AR226-0115
|
YGZ6Xnr788gnbdGXk8pwMvD98 |
26 |
|
The report from WARF Institute, Inc. details the skin and eye irritation testing of a product submitted by 3M Company, concluding that the product shows no skin irritation but does cause eye irritation.
|
1975 |
AR226-0127
|
5bYjbNyV655XQpx3xgRzyRGgR |
9 |
|
The document reports on a biodegradation test conducted by 3M Company on a mixture containing 6% PFOS, revealing high Chemical Oxygen Demand (COD) and varying Biochemical Oxygen Demand (BOD) results, but lacks sufficient characterization of the test substance and methodology.
|
1975 |
AR226-0689
|
bKJqrDZJZ9LKYJYXvawQYdRy |
4 |
|
The document reports on an acute toxicity test conducted on juvenile Pimephales promelas (fathead minnows) using a mixture containing 6% PFOS, indicating that the test sample, FC-201, had insufficiently characterized purity and may not accurately reflect the toxicity of its fluorochemical components.
|
1975 |
AR226-0690
|
L6kd90qDJp3BbXKRE39OadJ7 |
7 |
|
The document details an acute toxicity test conducted on the aquatic invertebrate Palaemonetes pugio using a mixture containing 1.34% PFOS, indicating that the test was performed to assess the toxicity of this perfluorinated compound in a controlled environment.
|
1975 |
AR226-0723
|
4J3DbooZxajmMqp3VYQrg6L6e |
12 |
|
The document reports on a biodegradation test of a mixture containing 1.34% perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1975, providing various organic carbon measurements but lacking detailed methodology and conclusions.
|
1975 |
AR226-0736
|
oeoV2JbQaEYa75Qd1rYeBYbnR |
5 |
|
The document reports on an acute toxicity test of a mixture containing 1.34% PFOS (perfluorooctanesulfonate) conducted on juvenile Pimephales promelas, indicating potential toxicity levels but lacking comprehensive characterization of impurities and specific test conditions.
|
1975 |
AR226-0740
|
pm6LaVjRVEm36B4V23JNjk4KX |
3 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the study was terminated prematurely and lacks reliable data on the degradation potential of the fluorochemical component.
|
1975 |
AR226-0776
|
JrydO9zeOaZkXEyG23dQzQ3v2 |
3 |
|
The document details an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 0.92% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating potential toxicity levels based on the test conditions and methods used.
|
1975 |
AR226-0795
|
6B8xKJ7Bv0mXYVBggv2Vy2Y86 |
9 |
|
The document details an acute toxicity test of a mixture containing 1.0% PFOS on fathead minnows (Pimephales promelas), conducted in 1975, with unspecified test conditions and results indicating the need for caution due to the presence of impurities in the test sample.
|
1975 |
AR226-0826
|
8RpKmoNMmgakR6Q4Qpv2EYvDy |
6 |
|
The document summarizes multiple biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) as part of FC-600, indicating that total organic carbon removal was between 90-91% and dissolved organic carbon removal ranged from 79.9-94% over 28 days.
|
1975 |
AR226-0825
|
65RKvDawmvd4nxajbm7D19Kyo |
41 |
|
The document reports on an acute toxicity test conducted on bluegill fish (Lepomis macrochirus) using a mixture containing 1.0% perfluorooctanesulfonate (PFOS) and various other components, indicating that the test was performed under static conditions with specific water chemistry parameters noted.
|
1975 |
AR226-0827
|
G6NqVOD24q67xLKjMgRQe8Eex |
5 |
|
The document details an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 0.58% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating the test's methodology and conditions but noting that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1975 |
AR226-0872
|
5bdmxDQgkayX35xaDGm8gBEv0 |
9 |
|
This document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.58% perfluorooctanesulfonate (PFOS) from a 3M production lot, with the study following EPA guidelines and measuring various environmental parameters over a 96-hour exposure period.
|
1975 |
AR226-0874
|
zQdEvQNJxRbVEXLNyV6Eg4zqm |
16 |
|
The document reports on an acute toxicity test of a PFOS-containing mixture (FC783) conducted on bluegill sunfish (Lepomis macrochirus) to determine its effects, using standard EPA methods, with a 96-hour exposure period.
|
1975 |
AR226-0876
|
YDb3Gj1EzEgqDVBG9g39eBqz8 |
13 |
|
The document reports on an acute oral toxicity study of a 25% w/v suspension of a material identified as 3M Company - T-1388, which resulted in an LD50 of less than 0.63 gm/kg in male and female albino rats.
|
1975 |
AR226-0326
|
Ev7y6bLkL32NbMG3MR9R5E3vL |
2 |
|
The document reports on a water solubility study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), conducted by 3M in 1977, which found that the substance has a solubility in the mid part per billion range, although the purity of the sample and the characterization of the test water were not adequately documented.
|
1975 |
AR226-0344
|
gwmM3Voa60jvv6Xj3N06a1LG |
5 |
|
The document reports on a water solubility test for N-methylperfluorooctane sulfonamidoethanol (N-MeFOSE Alcohol) from a 3M lot, indicating a solubility of 0.82 mg/L, but notes concerns about the study's reliability due to insufficient characterization of the test substance and methodology.
|
1975 |
AR226-0367
|
JNy3LXKXV60YKGG90ddnYBk1v |
12 |
|
The document reports on an acute toxicity study of N-methylperfluorooctane sulfonamidoethanol (FC-3925) on bluegill sunfish, indicating that the highest concentration tested did not induce 50% mortality, and the test substance precipitated over the course of the experiment.
|
1975 |
AR226-0372
|
zQVXb2exwDNvQkGL1Qk2k0B37 |
4 |
|
The document reports on acute toxicity studies of N-methylperfluorooctane sulfonamidoethanol (N-MeFOSE Alcohol) on Daphnia magna, indicating that the concentrations tested exceeded the water solubility of the substance and detailing the test conditions and water chemistry parameters.
|
1975 |
AR226-0373
|
K6o2k42d7J8xLbx119YmMyd1K |
13 |
|
The document is a report from Biosearch, Inc. detailing a primary skin irritation study conducted on a material from 3M Company (T-1395) using albino rabbits to assess its potential irritative effects on intact and abraded skin, with results summarized in a table.
|
1975 |
AR226-0421
|
6w5bedbvmMVjBK3QN99wjNBQ4 |
4 |
|
The document reports on a primary eye irritation study conducted by Biosearch, Inc. for 3M Company on a test material (T-1395), concluding that the substance does not cause ocular irritation and therefore requires no cautionary labeling under the Federal Hazardous Substances Labeling Act.
|
1975 |
AR226-0422
|
bJbBkJD38x6qjJVrXza7Y3a3 |
4 |
|
The document reports on a primary eye irritation study conducted by 3M Company on a test material (T-1395) to evaluate its potential irritant effects when instilled into the eyes of albino rabbits, concluding that the material's irritancy level is detailed in the accompanying results table.
|
1975 |
AR226-0423
|
mBJO1OwxwvQrB5QqNRGD68MpJ |
3 |
|
The document reports on an acute toxicity test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) conducted on the fish species Pimephales promelas, revealing a 96-hour LC50 value of 766 mg/L.
|
1975 |
AR226-0504
|
OED6RMaqqQVJLVwxZYNR8RdJM |
7 |
|
The document reports on an acute toxicity test of Perfluorooctanesulfonate (PFOS NH4+ salt) conducted on the fish species Pimephales promelas, revealing a 96-hour LC50 value of 100 mg/L with 100% mortality observed at the highest concentration of 150 mg/L.
|
1974 |
AR226-0195
|
dYrEaGg0mKm4JwnZXmvdwM1Y0 |
11 |
|
The document reports on a biodegradation test of Perfluorooctanesulfonate, Ammonium salt (PFOS NH4+ salt) conducted by 3M Company, indicating that some portion of the substance biodegraded in aerobic environments, although the results primarily reflect the biodegradation of the isopropanol component rather than PFOS itself.
|
1974 |
AR226-0196
|
vjqMJx9oV5w1E5VkBvvLDn3q |
10 |
|
The document outlines a research proposal by 3M in collaboration with Johns Hopkins University to analyze serum samples for fluorochemicals, including PFOS and PFOA, from out-of-county residents in the CLUE I and CLUE II studies conducted in 1974 and 1989, aiming to assess detectable levels and changes over time.
|
1974 |
AR226-0020
|
6bkVX47ZOMvyjMqK19p1M6YGR |
6 |
|
The document describes an algicidal activity test of a mixture containing perfluorooctanesulfonate (PFOS) and other components, conducted on algae species Chlorella pyrenoidosa and Phormidium inundatum, to assess the toxicity of the fluorochemical component.
|
1974 |
AR226-0721
|
K6rnJBaKvmmwRQ85Yn24kr9Rx |
10 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on juvenile rainbow trout, indicating the test was conducted under static conditions for 96 hours with various concentrations of the substance.
|
1974 |
AR226-0722
|
mm1vegVLDEQMdJJnXmX6NByKZ |
4 |
|
The document reports on an acute toxicity test of a PFOS-containing mixture (FC206) on fathead minnows (Pimephales promelas) conducted in 1974, noting that the data may not accurately reflect the toxicity of the fluorochemical component due to the presence of impurities.
|
1974 |
AR226-0781
|
3Nbv0ra91Zrrj2Nd8BD8yde6J |
7 |
|
The document reports on an acute toxicity test of a mixture containing 0.67% perfluorooctanesulfonate (PFOS) on juvenile rainbow trout (Salmo gairdneri), indicating that the study was conducted under unspecified conditions in 1974, with a focus on the effects of varying concentrations of the test substance.
|
1974 |
AR226-0782
|
3JM15pK4w9w3jE04BLen8znkJ |
3 |
|
The document details an acute toxicity test of a PFOS-containing mixture (FC-206) on the aquatic invertebrate Daphnia magna, noting its composition and the testing methodology, although it indicates that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1974 |
AR226-0787
|
kDZEa1byEzEGmwYDd4bdo4JYb |
8 |
|
This document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic invertebrate species Gammarus fasciatus, revealing a 48-hour median tolerance limit (TL50) value of 5170 mg/L.
|
1974 |
AR226-0788
|
3pm4v8ygx8Xr29X8jJ6d6NwE |
8 |
|
The document reports that the 96-hour LC50 for the perfluorinated compound Perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) tested on fathead minnows (Pimephales promelas) by 3M Company was determined to be 30 mg/L.
|
1974 |
AR226-0400
|
E3zXORqj7G9eZyDdjz1amwL4 |
4 |
|
The document reports that the 96-hour LC50 for the test substance perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) was determined to be 34 mg/L for the fathead minnow (Pimephales promelas) in a study conducted by 3M Company.
|
1974 |
AR226-0401
|
Oz06Z5v42QKOvyMpY8VLa4npX |
4 |
|
The document reports on a bioaccumulation study of the perfluorinated compound 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate (B1228) conducted by 3M Company, indicating that the substance is not bioaccumulative in carp (Cyprinus carpio) under the tested conditions, although concerns about the purity and
|
1974 |
AR226-0415
|
2q80v9JZQNnDmm7DD14d767oN |
97 |
|
The document reports a static acute toxicity test conducted by 3M on perfluorooctanoic acid (PFOA) using fathead minnows (Pimephales promelas), determining a 96-hour LC50 value of 440 mg/L.
|
1974 |
AR226-0498
|
zow91nZYK3b933weDw5yLa98R |
3 |
|
This analytical report from Centre Analytical Laboratories details the characterization of surface water samples collected in Cleveland, Tennessee, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
1973 |
AR226-0671
|
JJ39O3K1OYxNONRnwea2BjxYZ |
8 |
|
The document is an analytical report from Centre Analytical Laboratories detailing the fluorochemical characterization of drinking water samples from Cleveland, Tennessee, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
1973 |
AR226-0070
|
BXnVvqvQV5VJD9JnEyYa8GNk |
8 |
|
The document reports on histopathological examinations of fathead minnows (Pimephales promelas) exposed to 14C-78.02, a perfluorinated compound, to assess sub-lethal effects following a previous egg and fry test conducted for 3M Company.
|
1973 |
AR226-0109
|
Vj7jDQ6LwKdGNJjdpOvq4eEyj |
7 |
|
The document summarizes biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) as part of FC-203, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn due to insufficient method documentation.
|
1973 |
AR226-0710
|
J31jZ5oQzbdjkZbYKnOr1vM0v |
15 |
|
This document reports on acute aquatic toxicity testing of a mixture containing perfluorooctanesulfonate (PFOS) from 3M production lots, revealing varying 96-hour LC50 values ranging from 0.061% to >1000 mg/L across multiple studies.
|
1973 |
AR226-0717
|
MpR5m8ynm2mBzZZxK0oNz4Xj |
28 |
|
The document reports on a microbial inhibition test involving a mixture containing 1.34% perfluorooctanesulfonate (PFOS) produced by 3M, but lacks detailed methodology and conclusive results due to insufficient characterization of the sample and impurities.
|
1973 |
AR226-0720
|
45ogNJd4QpQ30QDbpJVMzNwN |
8 |
|
The document reports on a microbial inhibition test involving a mixture containing 0.67% perfluorooctanesulfonate (PFOS) produced by 3M Company, but lacks detailed methodology and conclusive results.
|
1973 |
AR226-0780
|
wBd6Oy8Dg4MqBp0GNw7okRYd |
7 |
|
The document reports on a primary eye irritation study conducted by 3M Company using a test material (T-2038CoC) on albino rabbits, concluding that the material is not a primary ocular irritant and requires no cautionary labeling.
|
1973 |
AR226-0292
|
ZJNOdjp0zwp28z8oqrRqOBRQY |
3 |
|
The document details a primary skin irritation study conducted by 3M Company on a material identified as T-2038CoC, using albino rabbits to evaluate the degree of irritation caused by the substance when applied to both intact and abraded skin.
|
1973 |
AR226-0293
|
jBvddOJd4kK9LO6Mym61B4ZxZ |
3 |
|
This document reports on a chronic toxicity study of perfluorooctanesulfonate (PFOS) conducted by E G & G, Bionomics for the 3M Company, which found a 30-day no observed effect concentration (NOEC) of 1 mg/L for the fish species Pimephales promelas.
|
1972 |
AR226-0107
|
zQwo734o7xqeQGgVnY0DjMrGB |
2 |
|
The document details a chronic toxicity study on N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol) conducted on fathead minnow eggs, following EPA methodology, to assess its effects on survival and hatching rates over a 32-day exposure period.
|
1972 |
AR226-0357
|
YDXoYVe2KRojVj4k0zy61RVL8 |
6 |
|
The document details a chronic toxicity study on perfluorooctanoic acid, ammonium salt (PFOA), conducted by the U.S. EPA in 1978 using fathead minnows to assess the effects of the substance on fish survival and hatching rates.
|
1972 |
AR226-0501
|
aeLEJDO9awb7Q8jGdbyg23oN |
6 |
|
This document is a letter report from URS Greiner Woodward Clyde to the EPA summarizing preliminary findings from a small mammal trapping investigation at the Dry Run Landfill in Washington, West Virginia, aimed at assessing small mammal densities and potential abnormalities in relation to PFOA contamination.
|
1972 |
AR226-1242
|
j0JbnMx7qM21vgmb7o7V8779 |
14 |
|
The document details an acute toxicity test of a PFOS-containing mixture (FC-206) on mummichog fish (Fundulus heteroditus), indicating that the test was conducted using standard methods with specific conditions and parameters, but notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1971 |
AR226-0783
|
v1YV0mw03kVbaYbyGaDMZYZrY |
10 |
|
The document reports on an acute toxicity test of a mixture containing 0.67% PFOS, conducted on grass shrimp (Palaemonetes vulgaris) using standard methods, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization of impurities.
|
1971 |
AR226-0784
|
6bOgQqqzbaDGq01bvvXdY6w1E |
10 |
|
The document details an acute toxicity test of a mixture containing 0.67% PFOS on the fiddler crab species Uca pugilator, conducted using standard methods in 1974, with specific test conditions and parameters outlined.
|
1971 |
AR226-0785
|
jgzjJB56mQ70qyJENZXXwxnX5 |
10 |
|
The document details an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 1.34% perfluorooctanesulfonate (PFOS) and various other components, highlighting the methodology and conditions of the bioassay performed in 1972.
|
1970 |
AR226-0716
|
QgdKG6avXw85O1v5J7q6ejw0E |
10 |
|
The document details an acute toxicity study of a mixture containing 1.34% PFOS (perfluorooctanesulfonate) on Daphnia magna, conducted using standard methods with specific test conditions and parameters, although it notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1970 |
AR226-0718
|
jyLJJe3GqKBDJ5meg24p2eD42 |
10 |
|
This document details an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the aquatic invertebrate species Gammarus fasciatus, with exposure concentrations ranging from 560 to 3200 mg/L over a 48-hour period.
|
1970 |
AR226-0719
|
BROXVZB6zxpa1GJO1Nb2e98ZE |
10 |
|
The document discusses bioaccumulation studies of FM3422 (N-Et FOSE alcohol) in bluegill sunfish and channel catfish, highlighting significant methodological deficiencies and uncertainties regarding the characterization of the substance and the identification of the toxicant involved.
|
1970 |
AR226-0351
|
GK03x218xXX177z40y4rkNY9N |
8 |
|
The document details an acute toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) using eastern oysters (Crassostrea virginica), indicating that the test sample, identified as FC-206, consists of 0.67% PFOS among other components, and outlines the methodology and conditions of the bioassay conducted.
|
1967 |
AR226-0786
|
g2Rq3d7zqEZ8Edqoz1JDOjxX3 |
8 |
|
The document outlines a protocol for an exploratory in-vitro absorption study of perfluorooctylsulfonate and ammonium perfluorooctanoate, conducted by 3M's Corporate Toxicology Department to assess skin absorption using the SkinEthic Reconstituted Epidermis Model.
|
1962 |
AR226-0182
|
pBqGoy0rwZnLZJpoKwoOR1oBX |
6 |
|
This document reports on a study conducted by 3M to investigate the mechanism of toxicity of Perfluorooctanesulfonate (PFOS) in adult rats, focusing on its potential to damage muscle mitochondria and cause conditions like rhabdomyolysis and lactic acidosis at high exposure levels.
|
1962 |
AR226-1724
|
ppyoKX7VOMZa2MdjgJ9q539mj |
14 |
|
A mortality study of employees at the 3M plant in Decatur, Alabama, conducted by University of Minnesota epidemiologists, found no significantly elevated standardized mortality ratios (SMRs) among workers exposed to perfluorinated compounds, with recommendations for an updated study to include additional mortality data.
|
1961 |
AR226-0032
|
LKDKn5EdLgvnxXwmB6r74Mj5 |
50 |
|
The document is a letter from 3M's Dr. William Weppner to EPA's Charles M. Auer, outlining the agenda for a meeting on December 14, 1998, to discuss the TSCA 8(e) filing regarding the presence of perfluorooctane sulfonate (PFOS) in blood samples from the general population.
|
1958 |
AR226-0622
|
qaOX6wYVmkkDp14DN5banDY5M |
1 |
|
This document reports on a study evaluating the incidence of myocardial infarction among male employees at the Washington Works Plant from 1956 to 1973, revealing 61 observed cases and comparing them to expected rates based on Du Pont Company statistics.
|
1956 |
AR226-1496
|
xz68NroLV7vakkEKny8GGazX0 |
8 |
|
This document is the final report of a case-control study investigating leukemia at the Washington Works site, sponsored by DuPont Co. and Polymer Products, with a focus on exposure assessment related to perfluorinated compounds.
|
1953 |
AR226-1308
|
82g4qR1grJGz1B3ddoGVmDNLy |
13 |
|
The document reports on a retrospective cohort mortality study of employees at the Chemolite Plant in Cottage Grove, Minnesota, conducted by Schuman and Mandel, which found no significant mortality findings related to perfluorooctanoic acid (PFOA) among the 3,688 workers studied, and recommends continued monitoring of the cohort's vital status.
|
1947 |
AR226-0470
|
ppRGXZEbK5z7DVydvq8YQy4mj |
16 |
|
The document reports that a primary skin irritation test conducted on T-3493 at Riker Laboratories, Inc. found it to be non-irritating to the skin of female albino rabbits, with no signs of erythema or edema observed.
|
1934 |
AR226-0305
|
jBrBZao8qa6B5RbMKEEzaoGJy |
10 |
|
This document reports the analysis of blood samples for perfluorooctanoate (PFOA) conducted by DuPont, detailing the concentrations found in various samples collected in December 1981.
|
1932 |
AR226-1611
|
06RjE1Zm4aGpggeMDV7R5n2kJ |
3 |
|
The document discusses the response of XENOS to FDA inquiries regarding a toxicity study of the chemical F n-3 9 2 4 conducted by RIKER Laboratories, specifically addressing liver changes observed in rats and confirming that the original findings remain unchanged.
|
1931 |
AR226-0263
|
2ZBM0NV1GOgzM9Da82RDVvog |
11 |