|
This is a final report from EnviroSystems Division of Resource Analysts, Inc. (Study Number 90171-3) detailing the static acute toxicity of FX 3820 to the daphnid, Daphnia aqua, conducted for 3M Company over 88 hours in December 1990.
|
— |
AR226-0119
|
K6rJ59VxodNVDBr0N3JoDV2mr |
17 |
|
The document reports on an acute oral toxicity study conducted by 3M Company on a material identified as T-2297CoC, which found that the LD50 in rats is greater than 0.05 gm/kg but less than 1.5 gm/kg, with observable symptoms at the higher dosage.
|
— |
AR226-0126
|
zopMwyXn8Z5gdrJz2gvb1MRwg |
2 |
|
The document reports on the acute toxicity of the substance FH 3820 to the alga Seleoastcum capricomutua, revealing a 96-hour EC50 of 255 µg/L and a no observed effect concentration of 125 µg/L.
|
— |
AR226-0122
|
jgByjeYOYa9p8BQ2aQrw3Jn9Z |
25 |
|
The document is a final report prepared for 3M Corporate Toxicology detailing a study on unscheduled DNA synthesis in rat liver primary cell cultures induced by PFOS, conducted by Covance Laboratories and compliant with EPA Good Laboratory Practice regulations.
|
— |
AR226-0132
|
9J68GMY87oGO62Rm91epQL9q6 |
36 |
|
The document is a final report from Covance Laboratories on a Salmonella-Escherichia coli mammalian-microsome reverse mutation assay conducted with PFOS, prepared for 3M Corporate Toxicology, indicating compliance with EPA Good Laboratory Practice regulations.
|
— |
AR226-0133
|
YjEdxb47r2G9NX6GmJb90g0dV |
43 |
|
This study report from the Centre for Xenobiotic Research investigates the levels of palmitoyl-CoA oxidation in frozen liver samples from 3M, specifically analyzing the effects of PFOS at a dosage of 20ppm, which resulted in a statistically significant increase in oxidation activity compared to the control group.
|
— |
AR226-0143
|
wgmv69GMwm82gm96M8bY16qjJ |
9 |
|
This document reports on a study conducted by 3M to investigate the effects of PFOS exposure during gestation on perinatal mortality and respiratory function in rat pups born to PFOS-exposed dams.
|
— |
AR226-1104
|
8VG5jDv07XGev12mJ98q24D7d |
23 |
|
This document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on rainbow trout, indicating a 96-hour LC50 value greater than 400 mg/L, suggesting low toxicity at the tested concentrations.
|
— |
AR226-0715
|
Oz3e53dQo9VzyYMJmZZyr4wxv |
4 |
|
This is a laboratory report from 3M Toxicology Services detailing the methodology and clinical information for a 48-hour fecal urobilinogen analysis, with specific notes on specimen collection and interpretation of results.
|
— |
AR226-0148
|
vV8pX3Yo5NEVyKj73Nxz9GBq9 |
26 |
|
This interim report presents preliminary data from a 26-week toxicology study on PFOS conducted in Cynomolgus monkeys by Covance for 3M, indicating that PFOS levels generally increased across all dose groups throughout the study duration.
|
— |
AR226-0151
|
VG79ayeD4VZjB2k27gL0JRvZN |
18 |
|
The document outlines a study protocol by 3M to evaluate the cytotoxicity of four test articles (T-6292, T-6293, T-6294, T-6295) using hepatocytes from rats, with the aim of determining suitable concentrations for further in vitro metabolism studies.
|
— |
AR226-0161
|
XzorrkDv8G9637Jq04dJ0MkMy |
19 |
|
The document discusses the metabolism of perfluorosulfonamide compounds in rat versus human hepatocytes, highlighting the detection of metabolites from the compound FX-12 (IX) and referencing a more sensitive analytical method used in the study.
|
— |
AR226-0164
|
KJKdBGw15Dyj1M5MQad971NEQ |
1 |
|
The report by Kendall B. Wallace, Ph.D., investigates the effects of six perfluorooctanonyl compounds (PFCs) supplied by 3M on mitochondrial bioenergetics in isolated rat liver mitochondria, finding that all compounds inhibited ATP synthesis through various mechanisms affecting mitochondrial function.
|
— |
AR226-0166
|
wDjk6wQ2L4BpBgep9o080MEjV |
10 |
|
The document discusses a study on the effects of perfluorinated arylalkylsulfonamides on the bioenergetics of rat liver mitochondria, specifically measuring mitochondrial membrane potential and respiration, supported by a grant from The 3M Company.
|
— |
AR226-0167
|
XRrNXLnq9bVMJ7jYJN6NdV4kd |
34 |
|
The document summarizes a study on the effects of various perfluorinated compounds (PFCs), specifically highlighting that the sulfonamide PF95M is a potent uncoupler of mitochondrial bioenergetics, with an IC50 of approximately 1.5 µM, raising concerns about its potential health impacts if bioaccumulated.
|
— |
AR226-0169
|
8RrvrvMGkDaDvxZ0wY4byEyDK |
3 |
|
This document is a composite report from 3M Environmental Laboratory detailing the results of analyses of human sera samples for fluorochemical compounds, including PFOA and PFOS, collected between March and April 1998, with an emphasis on the data's immediate relevance to human health concerns despite not adhering to Good Laboratory Practices.
|
— |
AR226-0178
|
8584YKK2ggR3q02mNa6eKj2RB |
66 |
|
The document outlines a study protocol from 3M's Strategic Toxicology Laboratory aimed at isolating liver sub-cellular fractions and quantifying perfluorooctane sulfonate (PFOS) contents to investigate its effects on serum cholesterol levels and liver function.
|
— |
AR226-0181
|
qkj0n1pZOm3YMnM2ayDOyyxKM |
6 |
|
This is a letterhead cover page from an unspecified organization, with no analytical content retained in the OCR.
|
— |
AR226-1111
|
zbz4q03a1RpQ2KrEXDn0e0zpa |
3 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-1118
|
rpyR7RpxY6mowQ8pLqLnXYqer |
1 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document contains confidential business information protected under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-1119
|
3QeEyEaR60pRbKragbqOvdNZx |
1 |
|
This document reports on a biodegradation test of a mixture containing 0.92% perfluorooctanesulfonate (PFOS) conducted by Pace Laboratories for 3M Company, noting significant Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) results but lacking detailed methodology and conclusions.
|
— |
AR226-0806
|
d0QoJrExY5y4qoJrkyVXomyb |
5 |
|
This document contains estrous cycle data for multiple animal groups, detailing the number of days in estrus, diestrus, and proestrus, along with mean cycle lengths and the number of cycles observed.
|
— |
AR226-1126
|
mqVd3Nk76KaV0xLRgp7j8R9vg |
18 |
|
The document is a request for a Science Advisory Board (SAB) review of a preliminary risk assessment of Perfluorooctanoic acid (PFOA) by the Office of Pollution Prevention and Toxics (OPPT), highlighting concerns about its potential systemic toxicity and carcinogenicity.
|
— |
AR226-1129
|
DDMYLRbaeJrpK0m6xe1E61VEM |
3 |
|
The document reports that the 96-hour LC50 for a mixture containing perfluorooctanesulfonate (PFOS) and other components, referred to as FC-780, was greater than 5000 mg/L, indicating low acute toxicity to the fish species Fundulus heteroclitus.
|
— |
AR226-0869
|
g23b67ar8w6a9pGB81L7zD9pa |
3 |
|
The document reports on biodegradation studies of a mixture containing perfluorooctanesulfonate (PFOS) as part of FC-780B, submitted by 3M Company, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn regarding the degradation potential of the fluorochemical component.
|
— |
AR226-0870
|
MJoqwGgxX39OemvzzEdJe5xZk |
36 |
|
This is a letterhead cover page from an unspecified laboratory, with no analytical content retained in the OCR.
|
— |
AR226-0289
|
9JMQKn61n9bnoL3ZgV4eZ3XeR |
7 |
|
The document reports on a guinea pig maximization study conducted by Hazleton Laboratories to assess the acute toxicity of a test substance (sample T-3609) for Minnesota Mining and Manufacturing, detailing the methodology and animal care involved in the study.
|
— |
AR226-0307
|
ymM0Kvpdo9YKx4qXnR1EVonvE |
23 |
|
The document is a Quality Assurance Certificate for a mutagenicity testing study of 2-[N-ethyl-N-perfluoroalkyl(C=1~8) sulfonylamino] ethylacrylate conducted by BML, Inc., confirming compliance with Japanese standards and the accuracy of reported results.
|
— |
AR226-0309
|
2jqKgen1MQ2zNkGgkYq4G18zb |
16 |
|
The document reports on a guinea pig maximization study conducted by Hazleton Laboratories for U.C. McCormick Minnesota Mining and Manufacturing, focusing on determining the irritant dose levels of a test material, potentially related to PFOA or PFOS, through topical application in young adult male albino guinea pigs.
|
— |
AR226-0315
|
kDaNDr8eLQ6y08DkBRx4R63vJ |
22 |
|
The document reports on an in vitro mammalian cell gene mutation test evaluating the mutagenic activity of T-5869, a substance produced by 3M Belgium, conducted in compliance with Good Laboratory Practice standards.
|
— |
AR226-0319
|
06BkZvXwNNpeQKjEbwyQL6JDR |
22 |
|
This document is a draft report for a 13-week dietary toxicity study of N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE, T-6314) conducted by Covance Laboratories for 3M, detailing the study's context, personnel, and timeline.
|
— |
AR226-0300
|
zbjREMbDwLK7j5bZbez6pXLp6 |
554 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-0930
|
DG4BZvrjGMbEEdJYRzOQn552o |
1 |
|
Unreadable document.
|
— |
AR226-1142
|
ExrNQvzVpx4yVVy8L8jJXdpbN |
1 |
|
This document is a final report on a cross-sectional study that measured levels of PFOA and six other fluorochemicals in the serum of 645 American Red Cross blood donors across six U.S. regions, utilizing high-pressure liquid chromatography/electrospray tandem mass spectrometry for analysis.
|
— |
AR226-1137
|
aNkLZVGMNgNg2bMbwp8wxYZ9 |
302 |
|
Unreadable document.
|
— |
AR226-0937
|
NE4mrZmkdeBXQ4Zo4ZJE4mE98 |
2 |
|
Unreadable document.
|
— |
AR226-0939
|
q0KOx8Ey31R2617rgODEXRLK |
2 |
|
The document outlines a meeting between the EPA and the Fluoropolymer Industry to discuss the safe manufacture and use of fluoropolymers, specifically focusing on fluorinated processing aids like APFO/PFOA, while addressing regulatory actions and industry safety practices.
|
— |
AR226-0938
|
RaaYnr90wkXLJk1ww558dVQLv |
7 |
|
Unreadable document.
|
— |
AR226-0942
|
dQJmz1rKrxKbpbmyakyERR5L5 |
1 |
|
The document summarizes studies conducted by 3M on the foaming characteristics of their AFFF products containing PFOS, focusing on their impact on wastewater treatment processes and the effectiveness of anti-foaming agents.
|
— |
AR226-0926
|
M4o8debJneQd4JEpKjEbe4Nrj |
59 |
|
Unreadable document.
|
— |
AR226-0944
|
rwNQYbXVKnjEn6gjM1KZgLDJ |
2 |
|
This is a final report from 3M Toxicology Services (HWI Number: 40200468) detailing an acute oral toxicity study of the test material T-5898 in rats, conducted according to OECD guidelines.
|
— |
AR226-0323
|
G5ZxzVEd9yz8VQd52G4Rvy9yY |
24 |
|
This is a final report from 3M (HWI Number: 40200469) detailing a primary dermal irritation/corrosion study of the test material T-5898 conducted on rabbits, following OECD guidelines.
|
— |
AR226-0325
|
dQ9wV1D3YE72kJO4p3DMrL64R |
11 |
|
This draft report details a 5-daily dose dermal absorption/toxicity study of the substance T-6684, sponsored by 3M, conducted on rabbits at Covance, with a completion date of July 11, 1997.
|
— |
AR226-0327
|
NExgZBMgOYDB1M8jr9BmknBZQ |
53 |
|
This document appears to be a laboratory report cover page related to the analysis of PFOSA, with references to various lot numbers and purity percentages, but lacks substantial analytical content.
|
— |
AR226-0331
|
jm5X0ze2kp57xMmevVy1x8BRO |
7 |
|
The document is an analytical report from 3M Environmental Laboratory detailing a comparative analysis of fluorochemicals, including PFOA and PFOS, in commercially obtained human serum samples, conducted under study identification number E02-1053.
|
— |
AR226-1150
|
8VDBNRXVBBoOppZ7Op9zDm3dZ |
52 |
|
This summary report outlines the findings from a 104-week dietary toxicity and carcinogenicity study of Perfluorooctane sulfonic acid potassium salt (PFOS; T-6295) in rats, conducted by Covance Laboratories, detailing the study's design and preliminary observations through Week 53.
|
— |
AR226-0956
|
wD9wON7y1naxrV9Y1RddEzN5D |
216 |
|
This document outlines a method for analyzing potassium perfluorooctanesulfonate (PFOS) and other fluorochemical surfactants in serum extracts using HPLC-electrospray/mass spectrometry, detailing the applicable compounds and matrices for testing.
|
— |
AR226-0025
|
2qj3D4e2a5QOxjawr8r7qyzkg |
9 |
|
The document is a technical report summary from 3M detailing the analytical methodology and support for the fate of fluorochemicals, specifically focusing on sorption-desorption studies of radiolabeled fluorinated compounds, including FC-95 and FC-143, in soil.
|
— |
AR226-0360
|
yr8doyXKJjQbzjBooKM9VmDN6 |
3 |
|
The document details an experiment conducted by Bio/dynamics Inc. to assess the acute inhalation toxicity of a dust form of T-2307 CoC, received from the Minnesota Mining and Manufacturing Company, using Sprague-Dawley rats as test subjects.
|
— |
AR226-0964
|
v6a2B2ZaKX3dE4B5g5pmEoE6q |
9 |
|
This is a Composite Analytical Laboratory Report from 3M detailing the quantitative analysis of fluorochemicals in environmental samples, encompassing multiple report numbers and analytical studies initiated between August 1999 and March 2000.
|
— |
AR226-0962
|
KGnwqr698Zryko6gJx5peYxLN |
133 |
|
This document reports on a study conducted by 3M Company to estimate the log Pow (octanol-water partition coefficient) for the substance MeFOSEA, using HPLC methods in accordance with OECD guidelines.
|
— |
AR226-0381
|
RpYOjv1a99q9pp6ZDGzLDGq8E |
17 |
|
The document outlines a study design for a 3M Microbial Metabolism Program aimed at optimizing conditions to enrich microbial populations capable of metabolizing fluorochemicals, including PFOA and PFOS, through various complex screening systems.
|
— |
AR226-0185
|
k96BgaJGaLeqM7jN0pV2D99gJ |
13 |
|
This is a cover page for the book "Fluorinated Surfactants and Repellents" by Erik Kissa, published by Marcel Dekker, Inc., detailing various aspects of fluorinated compounds, including their structure, synthesis, properties, and environmental impacts.
|
— |
AR226-1267
|
b52X2n7MKZvjYEZxbkKQEzrz0 |
7 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under the Toxic Substances Control Act.
|
— |
AR226-1268
|
91BdxgR8pneEE4BN4yNvVmazD |
1 |
|
The document discusses voluntary actions taken by Asahi Glass Fluoropolymers USA to evaluate and control emissions of ammonium perfluorooctanoate (PFOA) at their Bayonne, New Jersey site.
|
— |
AR226-1269
|
byzzgYEEQ2B0zyaoj0Z4rwoK6 |
1 |
|
The document discusses the Telomer Research Program's investigation into the biodegradation potential of 8-2 Telomer B Alcohol, a fluorotelomer intermediate, highlighting its physical-chemical properties and the challenges in testing due to its low water solubility and volatility, while also detailing the preparation of radiolabeled variants for quantitative studies.
|
— |
AR226-1283
|
x68Oeg1jzbZrBLyjkq0RjzM0 |
2 |
|
The document is a final report from the Kurume Laboratory Chemicals Evaluation and Research Institute in Japan, sponsored by Asahi Glass Co., Ltd., detailing a bioconcentration test of 2-perfluorooctyl ethanol (Test substance number K-1518) in carp, conducted in compliance with Good Laboratory Practice standards.
|
— |
AR226-1276
|
pmy7VwJ582qRg1GVnRKVvaGNB |
94 |
|
This document appears to be comments from the Ohio Environmental Protection Agency regarding water contamination issues related to C-8, discussing escalating safe level standards and screening levels for PFOS/PFOA.
|
— |
AR226-1164
|
YGegEr44MzDMbDVm9z017Jkpn |
19 |
|
This document appears to be a summary of various toxicity and environmental studies related to telomer manufacturing processes, including acute and chronic toxicity tests, biodegradation studies, and physicochemical property analyses, with references to DuPont submissions and interim reports.
|
— |
AR226-1293
|
37kJ2vQnKEo8yxMzZdMV5LMEn |
1 |
|
Unreadable document.
|
— |
AR226-1296
|
X7MD4bYBxea1e6LeGbqjBaypy |
1 |
|
Unreadable document.
|
— |
AR226-1297
|
wD0271pDmeqV6RwQ4rZ5qN1e6 |
1 |
|
This is a presentation from the APFN Work Group to the EPA, outlining the group's mission, membership, and ongoing efforts related to the safe manufacture and use of fluoropolymers, including the evaluation of APFN as a polymerization aid.
|
— |
AR226-1298
|
x19KrKEOjxBw0rqJkYZqR3x70 |
10 |
|
This document appears to be a meeting agenda from an EPA discussion on potential routes of exposure related to PFOA/PFOS, dated February 6, 2003.
|
— |
AR226-1300
|
reMZ9n236BNawkazVBDKaxzEe |
5 |
|
Unreadable document.
|
— |
AR226-1301
|
4vovxEYe0NOO1NX3Z1DVNMGe |
2 |
|
This is a presentation from the Telomer Research Program by Asahi Glass Company for the US Environmental Protection Agency, dated April 3, 2003, outlining the agenda and topics related to PFOA analysis and biodegradation studies.
|
— |
AR226-1302
|
Lg1M8E3yewY31wo5M34bJQ4wQ |
42 |
|
This is a letterhead cover page from an unspecified organization, with no analytical content retained in the OCR.
|
— |
AR226-1307
|
k9XBLjngbOv0zmO5Nd2qLRXpB |
4 |
|
The document is a confidential epidemiology surveillance report by DuPont detailing cancer incidence and mortality among employees at the Washington Works facility from 1956 to 1993, comparing observed cases and deaths to expected rates.
|
— |
AR226-1307
|
7O0NqOzngdZa5eedYdppMgvkR |
15 |
|
The document discusses the mechanics of film formation in aqueous film-forming foam (AFFF), highlighting the role of fluorocarbon surfactants in creating a low surface tension that enhances fire extinguishing efficiency and burnback stability on volatile hydrocarbons and fuels.
|
— |
AR226-1314
|
DDrXEweRZ1QDK4k2E98yj8rLo |
1 |
|
This is a TSCA NCIC Notification Form regarding confidential business information (CBI) documents, emphasizing the protection of such information under the Toxic Substances Control Act.
|
— |
AR226-1320
|
wDyGzmpJ63YGOy5O1waZjznN3 |
1 |
|
This document is a report on an acute eye irritation/corrosion study conducted on the substance T-7809 in rabbits, compliant with GLP standards and audited by NOTOX B.V. in the Netherlands.
|
— |
AR226-1323
|
vy2O9mQL3dg69JMEepb5Dm2rY |
10 |
|
The document reports on an acute toxicity study of the substance T-4127 conducted on Daphnia magna, ensuring compliance with OECD Good Laboratory Practice and relevant U.S. regulations.
|
— |
AR226-1336
|
m62DzYzzEGv1o05XqeOD4Zq0 |
21 |
|
The document reports on a 96-hour acute toxicity study conducted on zebra fish using the substance T-4127, ensuring compliance with GLP standards and relevant regulatory guidelines.
|
— |
AR226-1335
|
0g9qXpbwZzvd7xvzeYEe3EnXM |
38 |
|
The document reports on a 96-hour fresh water algal growth inhibition test conducted by NOTOX B.V. on the substance T-4127, ensuring compliance with OECD Good Laboratory Practice and relevant EPA regulations.
|
— |
AR226-1337
|
dYZx9B9EpRyQZ4MdbLvrENg70 |
37 |
|
The document reports on a range-finding study of 8-2 Telomer B Alcohol in rats, indicating that administration at 125 mg/kg/day resulted in significant decreases in body weight and increases in liver and kidney weights, with subsequent analyses planned for PFOA and PFNA levels.
|
— |
AR226-1340
|
G6BJzwwB7kaELjg43a1ygRqRn |
34 |
|
This is a final report from Resource Analysts, Incorporated detailing the acute toxicity of FC-120 to the fathead minnow (Pimephales promelas), conducted for 3M Company over a 96-hour period in March 1992.
|
— |
AR226-0383
|
OzGxLjx84XEeY20JNG216EZpv |
16 |
|
This laboratory report from 3M details an exploratory 28-day oral toxicity study in rats assessing the effects of PFOS and other perfluorinated compounds, with specific dosing levels and recovery periods for the test animals.
|
— |
AR226-0951
|
zbx9Vxjv20NJyDBxrmRY6m8va |
295 |
|
The document is a draft report of a 26-week capsule toxicity study on Perfluorooctane Sulfonic Acid Potassium Salt (PFOS) conducted in Cynomolgus monkeys, prepared for 3M by Covance Laboratories.
|
— |
AR226-0958
|
7MjJn43gezMk96VERy3oBxmwj |
438 |
|
The document reports on an acute oral toxicity study of the fluorochemical FC-143, produced by 3M Company, which determined the LD50 values in male and female rats to be 680 mg/kg and 430 mg/kg, respectively.
|
— |
AR226-0419
|
NG1exmDDXJzqBgRwD0omwM6kR |
13 |
|
The document reports on a 28-day oral toxicity study of FC-143, a perfluorinated compound from 3M Company, which found that mice fed concentrations of 1,000 ppm or more experienced high mortality rates and significant adverse health effects, including reduced body weight and muscular weakness.
|
— |
AR226-0444
|
jmZO3EM57azGOvyp3EwnK56bR |
17 |
|
The document is a final report on a primary eye irritation/corrosion study of the test material T-5898, conducted on rabbits to assess its irritative effects, in compliance with OECD guidelines.
|
— |
AR226-0969
|
QJYkZ3awqeGV6zM784ojE0874 |
22 |
|
The document is a report detailing a twenty-eight-day repeated dose oral toxicity study of a sample identified as D-1 in rats, conducted by Bio-Medical Research Laboratories Co., Ltd., focusing on the assessment of toxicity parameters.
|
— |
AR226-0968
|
ZJ5gOarpJqO1jgLbb0LRZ0ny0 |
219 |
|
3M is reporting to the EPA under TSCA Section 8(e) the draft results of a mortality study of workers at its Decatur, Alabama facility, which found no significant health risks associated with exposure to perfluorooctane sulfonate (PFOS).
|
— |
AR226-0980
|
qk1Mo8XVZrMpzKd78okrL0yqR |
3 |
|
The document summarizes a technical report regarding the analysis of FC-95 levels in the serum and livers of monkeys from a subacute toxicity study (IRDC 137-092) conducted by 3M, highlighting that initial feeding levels were too high, resulting in the death of all test animals.
|
— |
AR226-0982
|
N285Z8mDMOYj5YyprNwXn35bp |
3 |
|
This document is a TSCA 8(e) substantial risk supplemental notice from 3M regarding a two-year rat feeding study of N-Ethyl perfluorooctylsulfonamido ethanol (N-EtFOSE), which found a statistically significant increase in benign liver tumors in high dose female rats, corroborating earlier findings submitted to the EPA.
|
— |
AR226-0984
|
byE0MkR4KjYvqbYbX177dDYn1 |
3 |
|
The document is a technical report summarizing a 90-day subacute toxicity study of FM-3422, a perfluorinated compound, conducted on Rhesus monkeys, detailing dosage levels and findings related to serum and liver analysis.
|
— |
AR226-0985
|
M1gpVeoRyjanzLNwNB6e7YOk |
4 |
|
3M submitted a TSCA 8(E) substantial risk notice to the EPA regarding N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE), indicating that a 13-week dietary study in rats showed liver effects and reduced body weights at higher doses, consistent with toxicity observed in related perfluorooctanyl sulfonates.
|
— |
AR226-0988
|
OEQNDm94MzeeMdjmmB3BmK5eX |
3 |
|
The document is an analytical laboratory report detailing the determination of the presence and concentration of Perfluorooctanesulfonate (PFOS) in liver and serum samples from a 26-week toxicity study conducted by 3M on Cynomolgus monkeys, compliant with EPA Good Laboratory Practice standards.
|
— |
AR226-0981
|
9LONEGqjOZ8B8885QKZYBDZaV |
230 |
|
This document reports on a two-year oral toxicity and carcinogenicity study of fluorochemical FC-143 conducted by Riker Laboratories, Inc. for 3M Company, detailing various macroscopic and microscopic observations in rats, including findings of vascular mineralization and hepatocyte alterations.
|
— |
AR226-0438
|
G6V08EwVGv977j8Ewe9MEw8wq |
312 |
|
The document is an analytical report by the 3M Environmental Laboratory detailing the determination of PFOS, M556, PFOSAA, and PFOSA concentrations in the liver and sera of rats exposed to EtFOSE-OH as part of a two-generation reproduction study.
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AR226-0987
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Rpaw5BOxZ1ORxp4LnM604pVJk |
130 |
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This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
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AR226-0994
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m8DBdkGyVoX5XrBYDddd5LMg |
1 |
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This is a TSCA NCIC Notification Form indicating that the document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
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AR226-0995
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jyeMdEZZkpVJMKkLbq7qndBgQ |
1 |
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Unreadable document.
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AR226-0479
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Ddy7NzYxaNXE1GYR03wykq3N5 |
2 |
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The document provides a summary of various technical reports and laboratory studies conducted by 3M Environmental Lab on the environmental fate, transport, and biodegradation of PFOA and associated salts, including FC-143 and FX-1001, along with critiques from experts.
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AR226-0486
|
99orEL6Kz8abmmEoRgZnYM433 |
11 |
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This is a 3M Strategic Toxicology Laboratory report (Study TLI 001525) detailing an acute inhalation limit test for perfluoroctanesulfonyl fluoride (POSF).
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AR226-1358
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6RNg2V0rb4nqrydmYxnQVvXR |
17 |
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The document reports on an acute toxicity test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) on Daphnia magna, finding a 48-hour EC50 value of 126 mg/L based on nominal concentrations.
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AR226-0507
|
O1MLqj1w8791vgv8NYxM0O0RK |
13 |
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DuPont submitted study reports on 8-2 Telomer B Alcohol (CAS# 678-39-7) to the EPA for inclusion in Administrative Record 226, detailing findings from acute oral toxicity and mutagenicity assays without any claims of Confidential Business Information.
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AR226-1195
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4J0ppm7QGkL82vbNYJX4bO8xj |
2 |
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The document provides a summary of ecotoxicity studies conducted on PFOA ammonium salt (FC-143) by 3M Environmental Laboratory between 1977 and 1979, detailing various tests on aquatic organisms and noting the substance's purity and composition.
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AR226-0528
|
OzLpmGvLy1DZo6x3XmOeGJMJe |
13 |
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The document reports on a study conducted by 3M Chemicals on the metabolism of N-Ethyl Perfluorooctane Sulfonamido Ethanol (Net-Fose; T-6316) in Cynomolgus monkeys after a single capsule dose, completed by Covance Laboratories.
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AR226-0532
|
O1ERYjXgbq5KXj7MwExpjv7bL |
79 |
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The document details a toxicity test of perfluorooctylsulfonate (PFOS) on the aquatic plant species Selenastrum capricornutum, conducted by AScI Corporation, which involved a 96-hour exposure to a mixture of the test substance in water, with nominal concentrations reported and various environmental parameters monitored.
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AR226-0536
|
yqgawgo8k2KZZaMMEVLVGoJE |
13 |
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The document details a toxicity study of perfluorooctylsulfonate (PFOS) conducted on the aquatic plant species Selenastrum capricornutum, using a test sample produced by 3M, which was assessed for its impact on algal growth over a 96-hour exposure period.
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AR226-0537
|
wqxnVgGyD9k29yXK9KOvZOeMQ |
14 |